8 Best Nootropics for Dementia & Alzheimer's in 2023

Updated on March 14, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

Are you looking for ways to improve your cognitive function and protect against dementia?

If so, then the following nootropics may be the answer.

In this article, we’ll look at the best nootropics for dementia and Alzheimer's and how they can help you stay sharp as you age.

Best Nootropics for Dementia

  • Mind Lab Pro
  • Centrophenoxine
  • Alpha Lipoic Acid (ALA)
  • Coenzyme Q10 (CoQ10)
  • Creatine
  • N-Acetyl L-Cysteine (NAC)
  • Citicoline
  • Uridine Monophosphate

1. Mind Lab Pro

Mind Lab Pro is a natural nootropic supplement formulated to improve cognitive function and overall brain health. It contains 11 ingredients that are clinically proven to support the brain with the aim of preventing and reducing the risk of dementia.

The ingredients include Phosphatidylserine(1), Citicoline, Bacopa Monnieri, L-Theanine, and Rhodiola Rosea, among others. These ingredients are all shown to have beneficial effects on cognition, memory, focus, and attention. Mind Lab Pro is an excellent choice for those looking for an effective nootropic for dementia.

2. Centrophenoxine

Centrophenoxine is a nootropic supplement that has been used for many years to treat Alzheimer’s and dementia(2). It is a form of dimethylaminoethanol (DMAE) that has been combined with para-chlorophenoxyacetic acid (pCPA) to create a more effective and longer-lasting form of DMAE. It is believed to work by improving communication between the different parts of the brain, increasing the production of acetylcholine, a neurotransmitter that plays an important role in memory and learning.

Centrophenoxine also has antioxidant properties and is believed to reduce the oxidation of lipids in the brain, which can lead to cognitive decline in elderly people. Clinical trials have shown that Centrophenoxine may be beneficial in treating dementia and Alzheimer’s by improving memory, cognitive abilities, and overall cognitive functioning.

3. Alpha Lipoic Acid (ALA)

Alpha Lipoic Acid (ALA) is an essential fatty acid that is found in many foods. It is also a powerful antioxidant that has been shown to provide protection against oxidative stress, which is one of the main causes of dementia and Alzheimer's. ALA has been found to have a protective effect on neurons, which can help to reduce the damage caused by dementia and Alzheimer's. It can also help to improve cognitive function and memory by protecting the brain from oxidative damage.

ALA can also help to reduce inflammation, which can help to reduce the symptoms of dementia and Alzheimer's. Furthermore, it can help to reduce the risk of developing the condition and can even slow down its progression.

4. Coenzyme Q10 (CoQ10)

CoQ10 is an essential enzyme found in every cell of our body, and its main role is to produce energy. But it also has powerful antioxidant properties and can help protect cells from damage, which is why it has become a popular supplement for those with dementia. Studies suggest that taking CoQ10 can help improve cognitive function and slow the progression of dementia. It is thought to do this by reducing oxidative stress and improving mitochondrial function in the brain.

CoQ10 is generally considered safe and well-tolerated, although it can cause some mild side effects such as nausea, diarrhea and headaches in some people.

5. Creatine

Creatine is one of the most popular and most widely studied nootropics for dementia and Alzheimer's. It is a substance found naturally in the body, and is also commonly found in dietary supplements. Creatine has been shown to be beneficial in treating symptoms of dementia and Alzheimer's, as it helps to improve cognitive functions, memory, and concentration. It also has neuroprotective effects, which means it can help to protect nerve cells from damage.

Additionally, creatine can help to reduce inflammation, which is an important factor in preventing and treating dementia. While there is no cure for dementia or Alzheimer's, taking creatine as part of a comprehensive care plan can help to slow down the progression of the disease and improve quality of life.

6. N-Acetyl L-Cysteine (NAC)

N-Acetyl L-Cysteine (NAC) is an amino acid that has been studied for its potential to relieve symptoms of Alzheimer's and dementia. NAC is thought to work as an antioxidant, helping to reduce inflammation that can damage brain cells. It may also help to boost the production of acetylcholine, a neurotransmitter that plays an important role in memory function.

Studies have shown that NAC can help improve cognitive performance, reduce confusion, and improve mood in people with Alzheimer's and dementia. It is also considered to be relatively safe and well-tolerated, with few side effects.

7. Citicoline

Citicoline is a popular nootropic supplement that has been studied for its potential to help improve cognitive performance in people with Alzheimer's and dementia(3). This supplement works by increasing the levels of acetylcholine, a neurotransmitter that plays an important role in memory and learning.

Additionally, citicoline has been shown to reduce inflammation and oxidative stress in the brain, which can help improve brain health and reduce the effects of dementia. The supplement is generally considered safe and well-tolerated, though it can cause some mild side effects like nausea and headaches.

8. Uridine Monophosphate

Uridine Monophosphate, or UMP, is a key component of phospholipids, which are the building blocks of our cell membranes. It has been found to improve cognitive function, reduce dementia risk, and increase synaptic plasticity in animal studies(4). UMP has also been linked to increased dopamine release and improved memory in humans.

It is believed that UMP can help protect neurons from damage due to various diseases, including Alzheimer's and Parkinson's. For those with dementia and Alzheimer's, UMP can be a beneficial supplement to help protect their cognitive health.

How We Picked the Top Nootropics for Dementia

We employed a comprehensive evaluation method to identify the top nootropics for dementia management. We took into account effectiveness, ingredient quality, scientific evidence, brand reputation, product transparency, manufacturing process, user feedback, pricing, and overall value. By considering these factors, we were able to present a reliable and well-rounded list of the most effective nootropics for dementia.


We examined clinical studies and user experiences to evaluate the impact on cognitive function, specifically targeting cognitive decline, memory loss, and attention in dementia patients.


We closely inspected each formula, prioritizing natural, evidence-based, and high-quality ingredients known to support cognitive function in dementia.

Scientific Evidence

We consulted peer-reviewed studies and meta-analyses to confirm the effectiveness of key ingredients in supporting cognitive function in dementia.


We evaluated optimal dosages and ratios of ingredients, ensuring their alignment with established research for maximum efficacy in dementia care.


We verified the safety profile of each ingredient, considering potential side effects and interactions, and ensured adherence to regulatory guidelines. FDA-approved ingredients were prioritized.

Brand Reputation

We assessed the credibility and trustworthiness of each brand through customer reviews, expert opinions, and company background.

Product Transparency

We emphasized full ingredient disclosure, including the sources and concentrations, to enable informed consumer decision-making.

Manufacturing Process

We scrutinized manufacturing standards, prioritizing products made in certified facilities and following Good Manufacturing Practices (GMP).

User Reviews

We analyzed genuine customer feedback, bearing in mind testimonials detailing cognitive improvements and benefits related to dementia care.


We weighed product pricing, ensuring it was competitive and reflective of the nootropic's quality and effectiveness.


We determined overall value by considering the balance between price, quality, and effectiveness to ensure a solid return on investment for consumers.

How Can Nootropics Help with Dementia?

Nootropics, also known as “smart drugs,” are compounds that can provide mental support, improve cognitive performance, and enhance memory and learning. They are believed to be beneficial for people suffering from dementia and Alzheimer's disease. Nootropics can help improve focus, memory, attention, and problem-solving skills in people with dementia, as well as help reduce symptoms such as confusion and difficulty with language.

In addition, they can help improve mental clarity, energy, and alertness. There are many different nootropics available on the market today, each with its own unique benefits and potential side effects. Therefore, it is important to research each one carefully before deciding which is best for you.

What are the Benefits of Nootropics for Dementia and Alzheimer's?

Nootropics are a relatively new type of supplement that is gaining recognition as a potential aid in treating Alzheimer's and dementia. These supplements (https://wholisticresearch.com/best-nootropics/) are believed to help improve cognitive function and boost brain health, which can be an invaluable asset for those suffering from these conditions. While research is still ongoing, there are several potential benefits of taking nootropics for dementia and Alzheimer's.

best nootropics for dementia

For instance, some nootropic compounds, such as Ginkgo biloba and Bacopa monnieri, have been shown to improve memory and learning in dementia patients. Additionally, some nootropics, such as Alpha Lipoic Acid (ALA), have been found to be effective in reducing oxidative stress, which is a factor that contributes to cognitive decline in Alzheimer's disease.

Furthermore, certain nootropics, such as Coenzyme Q10 (CoQ10), have been found to have neuroprotective effects, which may help to protect the brain from further damage. Finally, some nootropics, such as N-Acetyl L-Cysteine (NAC), have been found to have neuroregenerative effects, which can help to repair and replace damaged neurons in the brain.

These potential benefits make nootropics an attractive option for improving cognitive functioning in those suffering from Alzheimer's and dementia. While further research is needed to fully understand the effects of nootropics on dementia and Alzheimer's, it is clear that these supplements could be a valuable asset for those struggling with these conditions.

The Safety and Side Effects of Taking Nootropics for Dementia

When taking nootropics for dementia, it's important to consider the safety and potential side effects of these supplements. Though many of the supplements discussed in this article have been approved by the FDA and are generally considered safe, it's important to consult with your doctor before taking any of them.

Additionally, side effects such as headaches, nausea, difficulty sleeping, and dizziness may occur when taking these supplements. It's important to monitor any symptoms that may occur and contact your doctor if they become severe.

While there is still much to be learned about the long-term effects of these supplements, it's important to understand that they may not be suitable for everyone.

Tips on Choosing the Right Nootropic for Dementia

When it comes to choosing the right nootropic for dementia, it is important to consider the individual needs of the person taking the supplement. It is important to understand the potential benefits and risks associated with each nootropic before use.

In general, individuals should consult with their doctor prior to taking any nootropic for dementia, as some may interact with other medications or have side effects. Additionally, it is important to read up on the research surrounding each nootropic and consult with a qualified health professional before making a decision.

Furthermore, it is essential to understand the dosage and how long the nootropic should be taken in order to maximize the potential benefits. With the right information and careful consideration, individuals can make informed decisions when choosing the right nootropic for dementia.

Conclusion: The Pros and Cons of Taking Nootropics for Alzheimer's & Dementia

When it comes to taking nootropics for Alzheimer's and dementia, it's important to weigh the potential benefits against the potential risks. Nootropics may help to improve cognitive function and provide relief from symptoms, but they can also come with side effects. Be sure to talk to your doctor before taking any nootropics, and follow the recommended dosage instructions carefully.

Additionally, be sure to select a quality, reputable brand of nootropic to ensure you are getting the best possible results. With careful consideration of the pros and cons, nootropics may be a beneficial addition to your dementia care plan.