How to Increase Neurogenesis?

Updated on December 9, 2022
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

If you are wondering how to increase neurogenesis, there are several options to consider. You can increase neurogenesis by taking certain supplements, incorporating nootropics, or making healthy lifestyle changes, such as exercising.

How to Increase Neurogenesis?

Nootropics Increase Neurogenesis

Neurogenesis is a process where new neurons are produced and recycled in the brain. This process involves a series of precursors, enzymes, and membrane transporters. Some nootropics increase neurogenesis by promoting the activity of these molecules. These compounds also support neuronal synthesis.

Neurogenesis is one of the most important processes in the human brain. It has been linked to improved motor functions, cognitive flexibility, and motivational modulations that involve reward pathways. Additionally, neurogenesis has been linked to overall brain health and longevity. Studies conducted by neuroscientist Sandrine Thuret have linked hippocampal neurogenesis with mood. When neurogenesis is disrupted, it results in neurodegeneration, which leads to age-related cognitive difficulties.

While neurogenesis is thought to occur only during early development, it can still occur in adults. However, it is not an easy process. Fortunately, some nootropics have been found to improve adult neurogenesis. While the benefits of neurogenesis are not immediately obvious, they are significant for overall brain health.

Researchers at BrainCells screened a wide range of antidepressant compounds and found that all of them increased neurogenesis in humans. Unfortunately, existing antidepressants are highly ineffective for patients and often have unwanted side effects. This is why scientists were determined to find compounds that would stimulate neurogenesis without causing unpleasant side effects.

Lifestyle Choices Influence Neurogenesis

Neurogenesis is a process that plays a key role in human brain plasticity and learning. Modulating this process can boost lifelong learning. Research on animals has indicated that a variety of factors influence brain cell proliferation. These factors include environmental factors, exercise, and even exposure to music. These findings support the importance of understanding how lifestyle choices affect neurogenesis.

Regular aerobic exercise promotes neurogenesis. What type of exercise is best depends on your body's needs and your age. Cycling, for example, has many benefits, including reducing stress and anxiety, and improving joint mobility. Another cardiovascular exercise that has been shown to promote neurogenesis is dancing. This exercise involves brain activity and coordination, making it a great way to get the brain working at its best.

Studies have also found a link between neurogenesis and better memory. But the connection between neurogenesis and depressive symptoms has not yet been established in humans. However, scientists found that a combination of physical activity and a healthy diet increased the number of neurons in the hippocampus of mice. Similarly, a diet rich in flavonoids, such as cocoa, can protect the hippocampus from damage due to aging and stroke in animal models. These findings suggest that flavonoids may improve brain health and promote neurogenesis in humans.

Exercise Increases Neurogenesis

Regular physical activity helps the brain grow new neurons. The increased number of new neurons is beneficial for cognitive functioning and reduces the risk of cognitive decline and Alzheimer's disease. In addition, regular physical activity boosts mood and helps you lose weight and stay healthy. It may also lower your risk of cancer and heart disease. In addition, it can help preserve existing brain cells.

Research shows that exercise increases neurogenesis in adult rats. The process is triggered when dormant stem cells in the hippocampus are stimulated by physical activity. When these stem cells are stimulated, their high levels of reactive oxygen species (ROS) are knocked down. This primed stem cell then enters a low-ROS proliferative state and gives rise to new neurons involved in mood, memory, and spatial learning.

Exercise increases neurogenesis in the dentate gyrus of the hippocampus, an area important for memory function. Although the function of these new cells is not entirely clear, they do appear to enhance learning, memory, and emotional state. Neurogenesis has been linked to physical activity and enriched environments.

Green Tea Increases Neurogenesis

Researchers have found that a compound in green tea, known as EGCG, influences the development and growth of important brain cells. This property may be responsible for the memory-boosting benefits of green tea. This compound may also protect the brain from neurodegenerative diseases such as Alzheimer's disease. Professor Yun Bai's team tested mice fed with EGCG and found that they showed improved learning and spatial memory.

EGCG is an antioxidant compound that is present in green tea leaves. This compound protects the brain from the effects of free radicals and other harmful substances. This substance is neuroprotective and has been promoted as a potential anti-aging remedy. Recent studies have shown that EGCG stimulates the proliferation of neural precursor cells in the dentate gyrus of C57Bl/6 mice. In addition, EGCG also promotes the development of immature new neurons.

However, there are several factors that can affect green tea's effects on cognitive function. The catechins present in green tea can be affected by the manufacturing process. For example, catechins in canned green tea are converted to epimers during sterilization and heating processes. The resulting polymer is known as (-)-gallocatechin gallate or GCG. This polymer is more stable and bioactive than EGCG.

Fish Oil Boosts Neurogenesis

Recent studies have found that blueberries, omega-3 fatty acids, and curcumin can boost neurogenesis. These nutrients also protect brain cells against certain neurotoxins and inflammation. They may even help fight Alzheimer's and other neurodegenerative disorders. However, some of these foods are expensive, and are not always easy to find.

There are several ways to get more of these compounds into your body. One way is by supplementing your diet with fish oil. Fish oil is an omega-3 fatty acid, which is known to increase the brain's neurogenesis. It also contains the neurotrophin BDNF, which is important for memory and learning.

Various animal studies have found that omega-3 PUFAs enhance neurogenesis. However, the underlying mechanism is not completely understood. The pleiotropic effects of omega-3 PUFAs on brain cell growth and neurogenesis have made it difficult to identify the specific mechanisms involved. But researchers have shown that omega-3 PUFAs can influence neurotrophin levels and modulate various transcription factors.

Several studies have shown that high levels of neurogenesis are associated with better health and a higher quality of life. Besides improved memory and cognitive abilities, a high level of neurogenesis protects the body against stress, improves overall mental health, and prevents depression.

Psychedelics May Increase Neurogenesis

Scientists at the Beckley Foundation and the Sant Pau Institute for Biomedical Research in Spain have discovered that harmine and tetrahydroharmine can induce the differentiation of stem cells into healthy neurons. The study is ongoing, but this discovery may have important implications for our understanding of neurogenesis.

The effects of psychedelics on neurogenesis are likely to be time and dose-dependent. Future studies should investigate whether these drugs influence BDNF signalling and neurogenesis at all levels, including receptor regulation and site-specific neurogenesis. In addition, future research should focus on the integration of newborn neurons.

Neurogenesis is a process in which new neurons are produced in the brain. These new cells interact with other neurons and form networks. Neurogenesis is one of the most important processes in the human brain, and many supplements are now claiming to harness its power. As a result, many psychedelic blogs have become very excited about the possibility of neurogenesis.

The effects of psychedelics on the brain have been studied in both animal and human models. Some evidence suggests that they may have antidepressant activity. In this study, researchers also discovered that the effects of psychedelics may affect the way the brain processes positive and negative affect. They also reported that psychedelics may alter valence domain units and the relationship between reward anticipation and response.

Vitamin E Regulates Neurogenesis

The role of Vitamin E in neurogenesis is not fully understood. While Vitamin E is well-known for its neuroprotective properties in adult animals, little is known about its role during embryonic development. Although Vitamin E may be protective against glutamate-induced neurotoxicity, it is not known whether it regulates neurogenesis or modulates its activity.

Neurogenesis is an important part of early brain development. It involves complex cell signaling pathways that stimulate neuronal cell proliferation, differentiation, and specification, and tissue formation. There are two main phases in neurogenesis: primary neurulation, which occurs in the caudal embryo, and secondary neurulation, which occurs in the hindbrain. Both stages involve the inflation of neural rods and expansion of the neural tube.

Vitamin E deficiency impairs neural crest cell migration. When NC are deficient in vitamin E, their expression of sox10 increases and they migrate ventrally away from the spinal cord. NC then undergo differentiation into cranial neurons, cardiac neurons, enteric neurons, sensory neurons, and glia.