How to Make Adderall More Effective (5 Proven Ways)

Updated on November 29, 2022
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

You might be wondering how to make Adderall more effective. There are several ways to increase the potency of this stimulant. These include avoiding vitamin C-rich foods, abstaining from alcohol, and getting enough rest. You will notice a difference in your performance if you do all of these things. This article also includes some lesser-known strategies.

how to make adderall more effective and longer lasting

Try these tips the next time you take Adderall:

1. Avoid Vitamin C-Rich Foods

avoiding vitamin c citric acid with adderall

You should avoid eating too much Vitamin C, such as orange juice, pineapple, or citrus fruits, to make Adderall more effective. This is because vitamin C slows drug absorption and reduces its peak effect.[1] To avoid this problem, avoid eating these foods several hours before or after taking Adderall. Vitamin C supplements are another thing to avoid. Vitamin C supplements may actually make Adderall less effective, so avoid them until your treatment is finished.

Citrus fruits contain citric acid, which blocks the absorption of ADHD medications such as Adderall. This means you should avoid eating citrus fruits for at least an hour before taking Adderall. This can result in increased side effects and decreased absorption. Citrus fruits are also diuretics, which can cause dehydration and poor absorption.

2. Avoid Consuming Alcohol

avoiding alcohol with adderall

Alcohol has a depressing effect on the body and can reduce Adderall's effectiveness. It may also reduce your sensitivity to other drugs. Avoid drinking alcohol on the day you take Adderall, and avoid using other drugs until afterward. It is preferable to avoid alcohol entirely than to get high and crash the next day.

Another myth about Adderall and alcohol is that you can drink while using it. This, however, is not recommended and can have a wide range of negative consequences. When Adderall and alcohol are combined, serious side effects can occur, including alcohol poisoning.[2] Many college students abuse Adderall and drink alcohol to counteract its effects. This is dangerous and may result in death. While it is perfectly safe to have one drink while on Adderall, it is not safe to have two.

3. Get Enough Sleep

more sleep for adderall effectiveness

Getting enough sleep is one of the most effective ways to make Adderall work better.[3] Avoid caffeine and other stimulants before bed and try to go to bed at the same time every day. It is also critical to avoid using smartphones or watching television before going to bed. Finally, make an effort to keep your room dark and quiet.

4. Drink Plenty of Water

avoiding dehydration with adderall

Aside from drinking plenty of water during meals, you should also take Adderall with plenty of water. This is critical because this medication is a diuretic and can dehydrate you.[4] If you do not drink enough water while taking Adderall, you will experience brain fog and will not benefit fully from the medication. It is critical to stay hydrated in order to reap the full benefits of this medication.

Depending on the dosage, you may experience a tight jaw or teeth grinding. This is a side effect of high Adderall dosages. You may also have climactic moments while chewing your teeth. If you do experience these side effects, you should drink more water to avoid them.

5. Consider Using Vyvamind or NooCube

supplements for making adderall more effective

Vyvamind is a nootropic brain supplement containing ingredients that have similar effects to Adderall. Vyvamind contains 75 mg of caffeine as well as the amino acids l-tyrosine and l-theanine, which help increase Adderall's potency.[5]

NooCube is yet another natural nootropic with l-tyrosine and l-theanine but no caffeine. In comparison to Vyvamind, it is more focused on long-term cognitive improvement.

Vyvamind is the best option if you want to boost the stimulating effects of Adderall or completely replace it.

NooCube is a better option if you want to take the edge off it while also reducing its side effects.


1“Adderall and Vitamin C Interactions.”,
2Rech, R H et al. “Interactions between amphetamine and alcohol and their effect on rodent behavior.” Annals of the New York Academy of Sciences vol. 281 (1976): 426-40. doi:10.1111/j.1749-6632.1976.tb27950.x
3Shalaby, Amr Said et al. “Sleep Deprivation & Amphetamine Induced Psychosis.” Psychopharmacology bulletin vol. 52,3 (2022): 31-40.
4SPELLER, P J, and D H STREETEN. “MECHANISM OF THE DIURETIC ACTION OF D-AMPHETAMINE.” Metabolism: clinical and experimental vol. 13 (1964): 453-65. doi:10.1016/0026-0495(64)90119-2
5Geis, L S et al. “Tyrosine influence on amphetamine self-administration and brain catecholamines in the rat.” Pharmacology, biochemistry, and behavior vol. 25,5 (1986): 1027-33. doi:10.1016/0091-3057(86)90081-x