10 Best Supplements to Take with Adderall (Science-backed)

Updated on July 8, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

If you're taking Adderall to boost your productivity, you must know which supplements and vitamins to take.

Several supplements can be taken along with Adderall to help improve your productivity, enhance focus, and increase concentration.

This article lists the best supplements to take with Adderall and how they can be used to maximize the drug's benefits.

The 10 Best Natural Supplements to Take With Adderall

Let's take a look at some of the Adderall supplement stacks or combinations and how they can be used to improve productivity, enhance focus, and increase concentration.

1. Vyvamind

Vyvamind is a powerful nootropic supplement that contains most of the other vitamins and amino acids listed below as ingredients.

Vyvamind is the best supplement to take with Adderall. It can be taken in addition to Adderall to increase its effectiveness and reduce its side effects, or even as an alternative to Adderall.

This is how the ingredients in Vyvamind complement Adderall:

  • Vitamins B6 and B12 help your brain sustain and maximize the cognition boost that Adderall provides.
  • L-Tyrosine is the foundation for dopamine, which Adderall significantly increases.
  • Citicoline is the foundation for acetylcholine, which increases the speed at which your neurons communicate.
  • L-Theanine decreases anxiety and jitters that you might experience with Adderall.
  • Caffeine Anhydrous enhances the stimulating effects of Adderall.

Overall, this means that Vyvamind significantly enhances the strength of Adderall while simultaneously decreasing its side effects.

Click here to visit the official website, Vyvamind.com >

2. B Vitamins

B vitamins are essential for healthy nerve function and metabolism, and low levels of these can lead to fatigue, depression, and poor concentration. Taking Adderall while having a B vitamin deficiency can worsen symptoms, so it is important to ensure you get enough B vitamins in your diet or through supplementation.

supplements to take with adderall vitamin b

These vitamins are generally necessary for red blood cell creation, energy metabolism, nerve cell growth and maintenance, and general cognitive function.

Performance Lab NutriGenesis® Multi contains a highly bioavailable vitamin B complex and many other essential vitamins for peak brain performance. Everyone should take vitamins with Adderall; this is the best option to prevent nutrient deficiency.

3. Vitamin D

If you don't already take vitamin D but have a prescription for Adderall, you might consider doing so.

supplements to take with adderall vitamin d

Vitamin D is an essential fat-soluble hormone that plays a crucial role in brain health. It carries a cholesterol backbone and has steroid-like effects, which can influence the brain's functioning. Vitamin D activates and deactivates enzymes in the brain and cerebrospinal fluid involved in neurotransmitter production, nerve growth, inflammation, and other processes. It also stimulates the most important antioxidant in the brain, glutathione, which helps protect against oxidative stress.

Studies have shown that higher vitamin D concentrations in the brain are associated with better cognitive function and memory (1). Additionally, vitamin D deficiency has been linked to neuropathology, such as Alzheimer's disease.

4. Vitamin C

Taking Vitamin C when taking Adderall is important for several reasons. Vitamin C helps to reduce the side effects of Adderall, such as insomnia, anxiety, nausea, and dizziness. Additionally, Vitamin C can help flush out excess amounts of Adderall in the body.

That said, it is important to be aware of the interaction between Vitamin C and Adderall and take steps to ensure that both are used safely and effectively. At high dosages, Vitamin C and other acidic supplements can interfere with the absorption of Adderall IR and XR into the body due to the latter's high alkaline pH.

Vitamin C has the ability to neutralize the active ingredients of Adderall, such as dextroamphetamine and amphetamine, which in turn reduces their effectiveness.

supplements to take with adderall vitamin c

If you are a new user of Adderall, stopping the drug's absorption can lessen your risk of having adverse effects. Vitamin C supplementation can also assist with weariness and ill-feeling after using Adderall.

5. Omega 3 Fatty Acids

Chronic inflammation is a side effect of long-term Adderall usage. It can eventually cause brain cell degeneration as your neurons become overworked from the increased central nervous system (CNS) activity, and their dendritic branches slowly wither away.

supplements to take with adderall omega 3 fatty acids

Taking omega-3 supplements, such as fish oil or krill oil, is one of the greatest strategies to prevent this and encourage healing. Fish oil supplements assist in battling chronic systemic inflammation and provide long-term protection against brain cell deterioration.

6. L-Theanine

In general, taking L-theanine is advisable when using any CNS stimulant. This amino acid can lower blood pressure, lessen stress, and encourage restful, deep sleep. L-Theanine is an amino acid found naturally in green tea that has been shown to have calming effects on the central nervous system. It modulates inhibitory neurotransmitters, selective serotonin, and dopamine receptors, which helps reduce stress and improve focus (2).

supplements to take with adderall l theanine

L-theanine and Adderall interact favorably, as L-theanine and caffeine dosages do (although Adderall and caffeine have different effects). You can choose among the available L-theanine supplements and decide which works best.

7. Magnesium

Magnesium lowers neuronal excitability. Its effectiveness controls overactive brain function. Some manufacturers mix it with threonic acid forming Magnesium L-threonate, which the body can easily absorb.

supplements to take with adderall magnesium

Additionally, it aids in blood pressure reduction, muscular relaxation, and, consequently, the promotion of sound sleep habits. If you intend to use Adderall, all of these factors are crucial because magnesium deficiency can leave you feeling uncomfortable, tense, anxious, and difficult to fall asleep.

8. Ashwagandha

Ashwagandha is one of the most dependable and potent natural anxiety-reducer supplements. This makes it an excellent supplement to take together with Adderall.

supplements to take with adderall ashwagandha

The primary mechanism of action of ashwagandha is to reduce blood cortisol levels. Your principal "stress" hormone is cortisol.

Like norepinephrine, it is tremendously helpful when released in response to injury or a threat. But chronically excessive cortisol is physically and mentally devastating (again, just like norepinephrine). Ashwagandha can significantly lessen signs and emotions of stress and anxiety by lowering cortisol.

9. L-Tyrosine

L-Tyrosine is an amino acid found naturally in foods like meat, fish, eggs, dairy products, nuts, beans, and soy. It helps produce mood-boosting neurotransmitters. It has been suggested that L-Tyrosine can help improve task performance in people with ADHD and other cognitive issues.

supplements to take with adderall l tyrosine

The mechanism by which L-Tyrosine works involves modulating levels of dopamine and norepinephrine in the brain. Increasing these neurotransmitter levels helps to provide a calming effect on the central nervous system. This can help reduce stress while maintaining the desired benefits of taking Adderall, such as improved focus and concentration.

10. Citicoline

Citicoline (cytidine 5'-phosphocholine, or CDP-choline) is a strong cholinergic agent. As a result, you can produce more acetylcholine (ACh), a necessary neurotransmitter, and phosphatidylcholine, which elevates choline levels in the brain (a fundamental building block of brain cells).

supplements to take with adderall citicoline

Citicoline, while using Adderall, is thought to increase the bioavailability and efficacy of Adderall in the brain. This increased effectiveness has been attributed to the neuroprotective and neuroregenerative properties of Citicoline, which allow for improved nerve transmission and communication in the brain.

This can lead to better focus and concentration and improved long-term memory formation. Furthermore, Citicoline has also been found to reduce side effects associated with Adderall use, such as insomnia, headaches, and stomach aches.

How to Take Advantage of the Nootropic Benefits of Adderall?

If you're using Adderall, you may wonder how to take advantage of its benefits and what you should do to get the most out of it.

The top recommendation is taking it first thing in the morning, while others during mid-day. Either way, you want to ensure you take it on an empty stomach.

You should always drink plenty of water after taking Adderall. It will help your body absorb the drug more effectively and will also help flush it out of your system. The bonus is that it is also an appetite suppressant so you may lose those unwanted fats while on it.

Adderall works best if you are not drinking too much caffeine while taking it. It can cause you to feel jittery, and you don't want to feel like that when you're trying to get some work done.

It's important to take Adderall correctly. You'll want to ensure you take the proper dosage promptly. If you're taking it for the first time, you should take the recommended dose. If taking it as part of a prescription, you should talk to your doctor to avoid Adderall interactions with other medications.

When you're taking Adderall, you want to make sure that you're getting all of the benefits that it has to offer. You should use it alongside a healthy diet, exercise regime, and other supplements.

You should also be careful about what you're doing while you're on it and ensure that you're not taking anything else that could harm you.

Typical Adderall Dosages

Adderall comes in two forms: Adderall, which is an immediate-release tablet, and Adderall XR, which is an extended-release capsule. The typical dosages for adults range from 5 to 60 mg daily, divided into multiple doses taken every 4 to 6 hours. For children, the dosage typically starts at 2.5 mg once daily.

Typical Adderall Dosages ForAdderall (immediate-release tablet)Adderall XR (extended-release capsule)
Adults5 mg to 60 mg per day, divided into multiple doses taken every four to six hours5 mg to 60 mg per day, divided into multiple doses taken every twelve hours
Children2.5 mg once dailyNot typically prescribed to children

When taking Adderall or Adderall XR, it's important to follow your doctor's instructions carefully and not exceed the recommended dosage. Too much can lead to serious side effects like heart problems and addiction.

Health Risks of Taking Adderall Medications

The side effects of Adderall include restlessness, nervousness, and trouble sleeping. You may also feel anxious, restless, or agitated.

Another disadvantage of this medication is that it is addictive. That is why doctors prescribe it for ADHD. It is so addictive that it is illegal to sell to those not prescribed by a doctor.

However, once you become addicted to this medication, you will be unable to stop taking it without going through a withdrawal process. This is because the brain becomes dependent on this medication. Many people using this medication to treat their ADHD have suffered from withdrawal symptoms.

The side effects of Adderall will go away after about a week. However, you may need to return to your doctor if you have severe side effects.

Supplements to Take with Adderall: Conclusion

There is no reason why taking Adderall with nootropic supplements would be wrong. This combination can be beneficial for most people. It all depends on how the supplements are taken. It would also depend on the person's lifestyle factors.

Many types of nootropic alternatives in the wellness industry can help you feel better. And based on this article, you can take some of them with Adderall to help you get the drug's benefits. Alternatively, you can try Vyvamind, a popular study drug with natural ingredients, so you won't have to worry about possible severe side effects. Vyvamind is one of the best supplements to take with Adderall.