3 Best Energy Supplements for 2024 (Top Pills Reviewed & Ranked)

Updated on February 6, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
Comprehensive review and ranking of energy supplements for enhanced vitality.

What are the best energy supplements?

In today’s fast-paced world, it’s no wonder that many of us find ourselves struggling with low energy levels. Thankfully, there are energy supplements on the market that can provide a much-needed boost.

In this guide, we will explore the top three energy supplements on the market, based on factual data and expert reviews. If you’re looking for a natural and effective way to increase your energy levels, then keep reading to discover the best options available.

Best Energy Supplements

1. Vyvamind

Vyvamind, a popular nootropic supplement, is known for its remarkable effects on boosting energy levels. This cognitive enhancer contains several key ingredients that contribute to its energizing properties.

A primary component of Vyvamind is Caffeine Anhydrous, a potent stimulant that increases alertness and reduces fatigue. Additionally, L-Theanine promotes a calm focus that prevents energy crashes often associated with stimulants.

Another important ingredient, L-Tyrosine, works to regulate neurotransmitters, allowing for better mental and physical performance according to research by Andrzej Slominski, Michal A. Zmijewski, and John Pawelek at the The University of Tennessee Health Science Center. This aligns with the use of L-Tyrosine in energy supplements, as it can contribute to improved cognitive function and energy levels. Their study provides a deeper understanding of the biological functions of L-Tyrosine, supporting its inclusion in energy supplements for its potential benefits in boosting mental and physical energy.

Citicoline, another excellent ingredient. According to research by J. F. Hatcher and R. J. Dempsey in 2002 at the Department of Neurological Surgery and Veterans Administration Hospital in Madison, Wisconsin, USA, Citicoline has shown neuroprotective effects in cerebral ischemia, which includes enhancing blood flow to the brain, resulting in improved cognition and increased energy. This aligns with the use of Citicoline in energy supplements, as it can contribute to improved brain function and energy levels.

B6 and B12 are the essential vitamins to boost energy. Vitamin B6 aids carb, protein, and fat metabolism, plus neurotransmitter synthesis for brain function and mood. Vitamin B12 supports blood cells and the nervous system. It converts carbs into energy.

These ingredients work together to provide users with a sustained energy boost while minimizing any side effects.


  • Enhances cognitive function
  • Improves focus and concentration
  • Increases mental clarity
  • Boosts memory and learning
  • Enhances alertness and wakefulness
  • Provides long-lasting energy


  • May cause mild side effects such as headache or nausea
  • Not suitable for individuals with certain medical conditions
  • Requires consistent use for optimal results
  • May not work equally well for everyone

Vyvamind naturally enhances your mental and physical energy levels. So you should definitely try it if you want a performance boost.

2. Performance Lab Energy

Performance Lab Energy is a highly effective nootropic supplement that revitalizes and boosts energy levels. Its formulation includes Magnesium, ALCAR, R-Lipoic Acid, Q10, PQQ and Black Pepper extract.

Magnesium supports energy production by aiding in the metabolism of carbohydrates and promoting ATP synthesis. Acetyl L-Carnitine enhances energy levels by facilitating the transport of fatty acids into the mitochondria for energy production. A study by Gustavo C. Ferreira and Mary C. McKenna, published in Neurochemical Research (Vol. 42, 2017), highlights the neuroprotective and energy-boosting properties of Acetyl-l-carnitine (ALCAR). The research indicates that ALCAR facilitates the transport of fatty acids into the mitochondria for energy production, thereby enhancing energy levels. It also suggests that ALCAR can improve energy status, decrease oxidative stress, and prevent cell death in various models of brain injury.

R-Lipoic Acid acts as a potent antioxidant, aiding in the conversion of nutrients into energy within cells. A study published in Voprosy Pitaniia (2019) by Voprosy Pitaniia et al., highlights the significant role of α-Lipoic Acid in energy metabolism. The research indicates that Lipoic Acid functions as a cofactor for mitochondrial enzyme complexes, enhances glucose uptake by cells, and has antioxidant effects that protect DNA, proteins, and lipids from oxidative damage

Coenzyme Q10 plays a crucial role in the electron transport chain, facilitating ATP synthesis and cellular energy production. A comprehensive study by the Department of Biochemistry, Biology, and Genetics at the Polytechnic University of the Marche, Ancona, Italy, support this claim and also underscores CoQ10’s effectiveness in improving physical performance, as well as its potential in addressing statin-related myalgias and enhancing sperm motility

BioPQQ (Pyrroloquinoline quinone) supports mitochondria function, promoting the generation of cellular energy. Research conducted by Yuji Itoh and colleagues in Japan revealed that daily administration of 20 mg of BioPQQ™ significantly improved cognitive functions, particularly attention and working memory, in elderly subjects. This study, which involved a randomized, placebo-controlled, double-blinded trial, also indicated an increase in cerebral blood flow in the prefrontal cortex, suggesting enhanced brain function. This evidence supports the inclusion of BioPQQ™ in energy supplements, highlighting its potential to boost cognitive performance and brain health.

BioPerine Black Pepper Extract enhances nutrient absorption, ensuring optimal utilization of energy-boosting ingredients in the supplement. For example, a study conducted by the Department of Cellular Biology, Histology, and Pharmacology at the University of Valladolid, Spain, found that the bioavailability of iron can be significantly improved when co-administered with black pepper extract, specifically a compound known as piperine. Iron is a micronutrient that aids athletic (and mental) performance by influencing the physiological functions involved in endurance sports by improving the transport, storage, and utilization of oxygen. This finding is particularly relevant for supplements like Performance Lab Energy, which includes this ingredient in its formulation. Such combinations can enhance nutrient absorption and utilization, thereby optimizing the energy-boosting effects of the supplement

These ingredients all provide energy at the cellular level while improving focus and mental clarity.


  • Enhances physical and mental performance
  • Increases stamina and endurance
  • Provides sustained energy without jitters
  • Enhances metabolism for better energy conversion
  • Helps combat fatigue and tiredness


  • May cause mild side effects in some users
  • May react with certain medication
  • Can be expensive for regular use
  • Limited availability in some regions

Performance Lab Energy’s reviews indicate how effective the supplement is for sustained energy. Also, the effects of its ingredients are well established. It’s a great option for you if you want to power through a big project.

3. Performance Lab Caffeine+

Performance Lab Caffeine+ is a nootropic supplement known for its powerful effects on energy and focus. Packed with natural ingredients, it offers a clean energy boost without the jitters or crashes commonly associated with caffeine consumption.

The key ingredient, caffeine, stimulates the central nervous system, promoting increased alertness and mental performance.(1)

Additionally, the supplement includes L-Theanine, a compound found in green tea, which synergistically enhances caffeine’s positive effects while reducing anxiety and promoting a calm and focused state of mind. Aaffeine consumption in low-to-moderate doses (~3–4 mg/kg) can improve energy balance in both physically active and sedentary individuals, as well as in obese or normal-weight men and women as shown in the study “The effect of caffeine on energy balance” by Eynav Harpaz, et al, published in the Journal of Basic and Clinical Physiology and Pharmacology in 2016.

To further support energy production, Performance Lab Caffeine+ contains L-Tyrosine, an amino acid that aids in the synthesis of neurotransmitters and combats mental fatigue.

Performance Lab Caffeine+ includes the best vitamins for energy and tiredness. B2 converts carbs to fuel and aids in fat and protein metabolism. B6 participates in over 100 enzymatic reactions for energy from food and neurotransmitter synthesis. B9 helps convert carbs to glucose, supports red blood cell formation, and sources include leafy greens and legumes. B12 assists in fatty acid and amino acid breakdown, red blood cell formation, and a healthy nervous system.

These ingredients provide a sustained energy boost and improve cognitive function.


  • Supports increased alertness and mental clarity
  • Offers a precise dosage of natural caffeine
  • Offers a prolonged energy lift
  • Provides a clean and sustained energy boost without the jitters


  • Some users might still experience jitters or restlessness
  • Potential dependency with prolonged use
  • Not suitable for pregnant or nursing women

Performance Lab Caffeine+ is a potent supplement with high nootropic benefits. Consult a specialist before using this supplement to avoid any unwanted reactions or effects.

How We Picked the Top Nootropics for Energy

We considered factors such as efficacy, ingredient quality, the reputation of the brand, transparency, manufacturing process, user experiences, price, and value. We evaluated each of these elements to curate a highly credible and thorough list of the best energy-boosting nootropics.


We examined clinical studies and user testimonials to measure energy enhancement, focusing on endurance, vitality, and mental clarity.


We meticulously reviewed each formula, prioritizing those with scientifically supported, natural, and superior-quality ingredients known to boost energy levels.

Scientific Evidence

We utilized peer-reviewed research and meta-analyses to authenticate the efficacy of key ingredients in boosting energy levels.


We verified the optimal dosage and ingredient ratios, making sure they are in line with existing research for peak effectiveness.


We confirmed the safety of each ingredient, considering potential adverse effects and interactions, and substantiating compliance with regulatory guidelines. We prioritized FDA-approved ingredients.

Brand Reputation

We assessed the credibility and reliability of brands through consumer reviews, expert recommendations, and company history.

Product Transparency

We valued full disclosure of ingredients, including their sources and potencies, to promote informed consumer decision-making.

Manufacturing Process

We scrutinized manufacturing standards, giving preference to products made in certified facilities and adhering to Good Manufacturing Practices (GMP).

User Reviews

We analyzed genuine customer feedback, emphasizing testimonials that recount energy enhancement and cognitive improvements.


We compared product prices, ensuring they were competitive and matched the quality and efficiency of the nootropic.


We evaluated overall value, taking into account the balance of price, quality, and efficacy to guarantee optimal return on investment.

How Energy Supplements Work

To comprehend the efficacy of energy supplements, it’s crucial to delve into how they work. The key lies in their ingredients. Products labelled as energy boosters usually contain substances that catalyze your metabolism and elevate your energy levels.

  • Nutrients Input: Energy supplements work in the body by supplying it with vital nutrients. Components like vitamins B, C, and magnesium play pivotal roles in the production of cellular energy from food. They enhance metabolic reactions that generate adenosine triphosphate (ATP), the primary carrier of energy within cells.
  • Natural Stimulants: Another strategy through which these supplements function is by utilizing natural stimulants like caffeine. Caffeine works by blocking adenosine receptors in the brain, reducing fatigue and enhancing alertness.
  • Adaptogens: Energy-focused supplements often feature adaptogens, i.e., plant extracts that help the body adapt to stressors and maintain physiological homeostasis. Through this mechanism, they stabilize energy flow and boost endurance.

Sharing common working principles doesn’t negate differences in the efficacy and safety profile of individual products. Therefore, the ‘best’ supplement would ideally be a blend of effectiveness and safety—compatible with your lifestyle and health profile.

Potential Side Effects of Energy Supplements

While energy supplements present a positive effect, potential side effects cannot be ignored. As the old adage goes, forewarned is forearmed.

  • Jitters: Too much caffeine can lead to feelings of anxiety, restlessness or jitters.
  • Insomnia: Energy supplements can make it challenging to wind down at the end of the day and could result in insomnia.
  • Dependency: Regular intake may lead to dependence, where you feel the need for such supplements to function properly.
  • Gastrointestinal Problems: Some ingredients may not agree with everyone’s stomach. This can lead to symptoms like nausea, bloating and diarrhea.
  • Interactions with other Medications: Energy supplements may interact with certain medications leading to unpleasant or harmful effects.
  • Allergic Reactions: Different people react differently to varying substances. A component in the supplement could potentially trigger an allergic reaction.

How to Use Energy Supplements Safely

One of the preliminary steps to using energy supplements safely is understanding that these products are not a substitute for basic dietary needs. They enhance mental and physical performance but should be used judiciously.

  • Consult with a Healthcare Professional: Always seek advice from healthcare providers before incorporating a supplement into your routine. Highlighting your medical history could guide their advice about the right type.
  • Stick to the Recommended Dosage: Overconsumption of energy supplements can lead to unintended side effects, such as high blood pressure, digestive issues, and heart problems. Always adhere strictly to the manufacturer’s instructions on dosage.
  • Avoid Late Evening Doses: Since these supplements aim to boost energy levels, taking them late in the evening might interfere with sleep patterns. Insufficient sleep can negate the benefits of the supplement.
  • Eat Balanced Diet: Energy supplements work best when combined with an appropriate diet. Consuming balanced meals will provide your body with additional nutrients needed for optimal function.
  • Vary Use: Continuous usage can result in tolerance, forcing you to increase dosage over time for effectiveness. Consider intermittent use of these supplements depending on energy needs.

Please remember to purchase your energy supplements from reputable outlets, manufacturers, or trusted e-commerce platforms.


In our fast-paced world, energy supplements have become essential for boosting vitality and mental acuity. This review highlights the top three energy supplements of 2024, backed by data and expert assessment.

Vyvamind stands out as a cognitive enhancer, blending ingredients for enhanced energy and cognitive performance. Performance Lab Energy capitalizes on dynamized B vitamins and natural amino acids for comprehensive vitality. Performance Lab Caffeine+ rounds up the selection with its unique blend of caffeine and L-Theanine, providing a clean and sustained energy boost.

These energy supplements undoubtedly offer enhanced productivity and focus, but a balanced and informed approach is essential for safe and optimal results.


When is the best time to take energy supplements?

Energy supplements are often best taken in the morning or early afternoon to avoid disrupting your sleep. However, consult with your healthcare provider for personalized advice.

Are there any supplements for those who suffer from chronic fatigue?

Yes, there are supplements specifically formulated for individuals who suffer from chronic fatigue syndrome.

Can natural energy boosters provide a long-lasting energy boost?

Yes, natural energy boosters can provide a sustained energy boost throughout the day.

Can I become dependent on energy supplements?

While most energy supplements are not addictive, over-reliance can occur. It’s important to use these supplements responsibly and not as a substitute for healthy lifestyle habits.

Can energy supplements improve athletic performance?

Some energy supplements can enhance physical performance by improving focus, reducing fatigue, and increasing stamina. However, results may vary based on the type of supplement and individual factors.

Sources, Studies, and Scientific Research
  1. Harpaz, Eynav, et al. “The effect of caffeine on energy balance.” Journal of basic and clinical physiology and pharmacology 28.1 (2017): 1-10. ↩