Maritime Pine Bark: Nootropic Benefits, Uses, & Side Effects

French Maritime Pine Bark Extract, commercially known as Pycnogenol, is a specialized extract from Pinus pinaster trees native to the southwest coast of France, which differs from regular pine bark extracts through its standardized concentration of procyanidins and unique bioactive compounds not found in common pine species.

Maritime Pine Bark supplementation offers a unique combination of procyanidins, bioflavonoids, and organic acids, which have been studied for their potential health benefits.

In this article, we will dive into the nootropic benefits, side effects, dosage, and mechanism of action that this powerful natural supplement offers human health and cognition.

What is Maritime Pine Bark?

Maritime Pine Bark is a natural extract derived from the bark of the French maritime pine tree (Pinus pinaster), which contains powerful antioxidant compounds called procyanidins and bioflavonoids that support various aspects of human health and cognition.

This type of pine tree native to the Mediterranean region is not just renowned for its majesty but also for the potent antioxidant properties found in its bark. 

The Maritime Pine Bark extract, rich in procyanidins, bioflavonoids, and organic acids, has been the subject of extensive clinical research due to its potential health benefits.

The high antioxidant activity of maritime pine bark extract is what has made it a focal point in herbal medicine. Antioxidants are crucial for protecting the body against oxidative stress caused by free radicals. This oxidative stress is associated with numerous chronic diseases, including heart disease, diabetes, and arthritis.

Maritime Pine Bark acts not only as an antioxidant but also has anti-inflammatory, anti-platelet aggregation, and vasorelaxant effects.

By scavenging free radicals, the antioxidant compounds in pine bark extract may help to maintain healthy blood vessels and support cardiovascular health.

Pros:

• Improves memory, focus, and mental clarity
• May reduce inflammation and improve heart health
• Increases blood flow and oxygen to the brain
• All-natural with robust evidence from clinical standardized studies

Cons:

• Not suitable for people on blood-thinning medications
• More clinical studies are needed to understand the safety of long-term use

Mechanism of Action

Maritime Pine Bark is an evergreen coniferous tree species native to the Mediterranean region. It is commonly known as Pinus pinaster and belongs to the genus Pinus of the family Pinaceae. 

The extract (Pycnogenol) is rich in procyanidin compounds from the maritime pine and has gained recognition due to its diverse clinical pharmacology.⁽¹⁾ Maritime Pine Bark consists of high levels of polyphenols, flavonoids, and proanthocyanidins (OPCs), such as catechin and epicatechin, which are powerful antioxidants.

They act as free radical scavengers, eliminating toxic oxygen molecules from the body’s cells and helping to maintain cell integrity and health. Other components include tannins, phenolic acids (such as gallic acid), and lignin derivatives (such as syringaldehyde), which also have unique antioxidant properties.

The extract of Maritime Pine Bark called Pycnogenol (PYC) contains 65 – 75% proanthocyanidins (procyanidins).⁽²⁾ This extract has been used for centuries due to numerous health benefits, such as boosting immune system function, anti-inflammatory effects, and improving circulation by widening blood vessels.

Maritime Pine Bark Extract supplementation can also improve cognitive functioning, elevate cerebral blood flow, and potentially prevent neurological illnesses such as Alzheimer’s or Parkinson’s. 

Additionally, taking pine bark extract additionally shows potential in treating conditions like ADHD (attention deficit hyperactivity disorder).⁽³⁾

Maritime Pine Bark Extract has been subject to many rigorous double-blind, placebo-controlled clinical studies showing evidence of its antioxidant properties and ability to act as an angiotensin-converting enzyme (ACE) inhibitor.⁽⁴⁾

Additionally, by improving the serum lipid profile of the heart and acting as a potent antioxidant, maritime pine bark may support coronary health and reduce the risk of atherosclerosis. Additionally, its ability to modulate platelet aggregation plays a critical role in maintaining healthy blood flow.⁽⁵⁾

Maritime Pine Bark Extract works in the body through five primary mechanisms of action, which include regulating cells against oxidative stress, scavenging free radicals, protecting DNA from damage, increasing antioxidant enzyme synthesis, and preserving other endogenous antioxidants from oxidative damage.

1. Regulates and protects cells against oxidative stress
2. Acts as a potent free radical scavenger
3. Protects DNA from damage
4. Increases the synthesis of antioxidant enzymes
5. Protects other endogenous antioxidants (vitamin C, vitamin E, and glutathione) from oxidative damage

Overall, the effect of French maritime pine bark has shown promising applications in cardiovascular, dermatological, and cognitive health management.

Complete Benefits of Maritime Pine Bark Extract

Maritime Pine Bark Extract offers an impressive range of health benefits beyond its cognitive effects. The extract’s unique composition of procyanidins, bioflavonoids, and organic acids contributes to its versatility as a natural supplement for overall wellness.

Cardiovascular System Benefits:

• Improves blood circulation and vessel elasticity
• Helps maintain healthy blood pressure levels
• Supports endothelial function and vascular health
• Assists in maintaining healthy cholesterol levels

Immune System Support:

• Enhances natural immune response
• Provides antioxidant protection against environmental stressors
• Helps regulate inflammatory responses
• Supports the body’s natural defense mechanisms

Skin Health Benefits:

• Increases skin elasticity and hydration
• Reduces signs of aging by supporting collagen production
• Protects against UV damage and environmental pollutants
• Improves overall skin appearance and texture

Athletic Performance Benefits:

• Enhances endurance and reduces recovery time
• Improves blood flow to muscles during exercise
• Reduces exercise-induced oxidative stress
• Supports joint health and mobility during physical activity

Metabolic Health Benefits:

• Helps maintain healthy blood glucose levels
• Supports insulin sensitivity
• Assists in weight management through metabolic support
• Contributes to overall metabolic balance

The comprehensive benefits of Maritime Pine Bark Extract make it a valuable supplement for those seeking natural support for multiple aspects of their health, from cardiovascular function to skin vitality and athletic performance.

Nootropic Benefits of Maritime Pine Bark

Evidence suggests that maritime pine bark could be a valuable addition to a nootropic regimen, potentially aiding various aspects of cognitive health through its antioxidant capacity and anti-inflammatory effects.

Here is an overview of the key nootropic benefits of using maritime pine bark extract.

1. Antioxidant Action and Cardiovascular Benefits

One of the primary mechanisms through which maritime pine bark acts is its antioxidant activity. It scavenges free radicals, thereby protecting the body’s tissues from oxidative stress, which can lead to chronic inflammation and various diseases.

The experimental comparison of Pycnogenol supplementation with other antioxidants has revealed its potent ability to improve the serum lipid profile. By positively affecting lipid levels, maritime pine bark may contribute to the protection against coronary artery disease.⁽⁶⁾

Regular use of Pycnogenol has been associated with the normalization of blood lipids, which in turn reduces the risk of plaque formation in the arteries. A healthier lipid profile can lead to improved cardiovascular outcomes and a lower incidence of coronary events.

Therefore, Pycnogenol may contribute to better heart health.

2. Improved Platelet Aggregation and Blood Pressure

Maritime pine bark may influence platelet aggregation, an essential factor in blood clot formation. By preventing excessive clumping of platelets, Pycnogenol helps maintain a smoother blood flow, which is crucial in preventing conditions such as deep vein thrombosis or heart attacks.⁽⁷⁾

The anti-aggregatory effect of this natural supplement underscores its significance in managing cardiovascular health and reducing high blood pressure.

3. Dermatological Effect of Pine Bark Extract

Using Pycnogenol can also be beneficial for skin health. Its antioxidant properties aid in protecting the skin from damage caused by UV radiation and environmental pollutants.

This protective effect is not only due to its ability to scavenge free radicals but also its role in synthesizing collagen and hyaluronic acid, which are vital components for skin elasticity and hydration. This property makes maritime pine bark a great nootropic for patients with mild skin conditions like eczema, or chronic dry skin.

3. Improvement of Cognitive Performance

Maritime pine bark extract has been used in addressing cognitive deficits following traumatic brain injuries. It acts as an antioxidant, which can mitigate oxidative stress, a factor that contributes to neuronal damage after such injuries. 

Given that a study found that maritime pine bark extract has been used to alleviate symptoms of knee osteoarthritis (such as pain and stiffness),⁽⁸⁾ its anti-inflammatory properties may also extend to neuroinflammation, which can impact cognitive function.

Additionally, maritime pine bark supplementation mitigates oxidative stress in postmenopausal women with osteopenia, who may experience cognitive decline as part of the aging process.

Lastly, the antioxidant properties of maritime pine bark could potentially slow the progression of neurodegenerative diseases by protecting neurons from oxidative damage.⁽⁹⁾

The nootropic benefits of commercial pine bark extract in humans have been explored in randomized controlled trials, providing a basis for its use as a cognitive enhancer.

4. Improvement of Metabolic Health

While not a direct nootropic benefit, maintaining a healthy body weight is crucial for overall brain health. Some studies suggest that the compounds in maritime pine bark may support metabolic health, which could indirectly benefit cognitive functions.

However, more research is needed to fully understand how metabolic health relates to cognitive performance.

5. Improvements in Erectile Dysfunction-Related Psychosocial Issues

While it may seem indirect, pine bark has been used to address mild to moderate erectile dysfunction. This can improve psychological and cognitive issues associated with the stress of sexual dysfunction.

6. Improvement of Focus and Drive

Regular supplementation with maritime pine bark mitigates oxidative stress, which can lead to improved mental clarity and focus, as oxidative stress is often associated with cognitive fatigue and fog.

Maritime Pine Bark vs. Other Antioxidant Supplements

When comparing Maritime Pine Bark Extract to other popular antioxidant supplements, several distinct advantages become apparent. This comparison helps illustrate why Maritime Pine Bark has gained recognition in the field of natural health supplements.

Maritime Pine Bark vs. Grape Seed Extract:

Both contain proanthocyanidins, but Maritime Pine Bark offers superior bioavailability and a broader spectrum of bioflavonoids. While Grape Seed Extract primarily supports cardiovascular health, Maritime Pine Bark extends its benefits to cognitive function, skin health, and joint mobility.

Maritime Pine Bark vs. Resveratrol:

Resveratrol is known for its anti-aging properties, but Maritime Pine Bark provides more comprehensive antioxidant protection. Maritime Pine Bark’s unique composition allows it to cross the blood-brain barrier more effectively, enhancing its nootropic benefits compared to resveratrol.

Maritime Pine Bark vs. Green Tea Extract:

Green Tea Extract contains catechins that offer antioxidant protection, but Maritime Pine Bark’s procyanidins demonstrate greater potency in neutralizing free radicals. Additionally, Maritime Pine Bark shows superior effects on blood flow and vascular health compared to Green Tea Extract.

Maritime Pine Bark vs. Vitamin C:

While Vitamin C is a powerful antioxidant, Maritime Pine Bark not only works synergistically with Vitamin C but also helps regenerate it in the body. This complementary relationship makes Maritime Pine Bark particularly effective when combined with Vitamin C supplementation.

Synergistic Combinations:

Maritime Pine Bark Extract works exceptionally well when combined with:

• Vitamin C for enhanced antioxidant protection
• Coenzyme Q10 for improved cardiovascular support
• Omega-3 fatty acids for comprehensive brain health
• Collagen for enhanced skin benefits

This comparison highlights Maritime Pine Bark’s unique position among antioxidant supplements, offering a broader spectrum of benefits and superior bioavailability compared to many alternatives.

Uses of Maritime Pine Bark

Maritime pine bark, derived from the Pinus pinaster tree, has been revered for centuries for its diverse medicinal properties. The bark extract, rich in powerful antioxidants like proanthocyanidins, offers a multitude of health benefits, making it a popular choice in herbal medicine and natural supplements.

Here are some of the most notable uses:

• Cardiovascular Health: Extracted from Pinus pinaster, maritime pine bark is used for improving blood circulation and reducing the risk of cardiovascular diseases.
• Anti-Inflammatory Properties: The use of maritime pine bark has been linked to the reduction of inflammation, beneficial for conditions like osteoarthritis where the evaluation of signs and symptoms shows significant improvement. Its anti-inflammatory qualities can also benefit respiratory conditions, potentially improving asthma and reducing the risk of lung infections.
• Skin Care: Maritime pine bark extract is incorporated in various skin care products due to its antioxidant properties, which help protect the skin from damage by free radicals and improve overall skin health.
• Cognitive Function: Among the many maritime pine uses, enhancing cognitive function is notable, especially in the elderly, by boosting memory and focus.
• Diabetic Care: It aids in managing blood glucose levels to reduce hypertension and improve the vascular health of diabetic patients.
• Allergies and Asthma: The anti-inflammatory effects of maritime pine bark are also employed in reducing allergic reactions and asthma symptoms.
• Eye Health: Regular supplementation with maritime pine bark extract can support vision by strengthening retinal capillaries.
• Sports Performance: Athletes may use maritime pine bark to aid in muscle recovery and reduce oxidative stress induced by intense physical activity.
• Joint Health: The supplement is often used for maintaining joint flexibility and aiding in the management of joint pain.

Where To Buy French Maritime Pine Bark

Although Maritime Pine Bark Extract is available in most online supplement stores, the quality of the product can vary significantly. There’s also a big difference between whether you stack (combine) Maritime Pine Bark Extract with other nootropic ingredients or take it as a standalone nootropic.

That’s why our top pick for the best manufacturer is Zazzee Natural, where you can source high-quality commercial maritime pine bark within fast-absorbing capsules.

Maritime Pine Bark Dosage

The recommended dosage for Maritime Pine Bark Extract ranges from 50-200 mg daily for adults, which is typically divided into 2-3 doses throughout the day for optimal absorption and effectiveness.

Studies have used dosages of 300 mg for a single capsule dose and 200 mg daily for 5 days to reach a steady state, 150 mg per day in 3 divided doses^, and 40-60 mg over a prolonged period of time.

Maritime Pine Bark Extract’s antioxidant action is observable at a dose of 50 mg/day, and higher doses that have been used up to 300 mg/day are recognized as safe and are taken without severe adverse effects.

Maritime Pine Bark for Different Age Groups and Demographics

The benefits of Maritime Pine Bark Extract can vary across different demographics, with specific advantages for various age groups and health conditions.

For Children and Adolescents

Maritime Pine Bark has shown promising results for children with ADHD, with studies suggesting improvements in attention, concentration, and hyperactivity. For adolescents, the extract may support cognitive development and provide antioxidant protection during this critical growth period.

Recommended dosage for children (6-12 years): 20-25 mg daily
Recommended dosage for adolescents (13-17 years): 30-40 mg daily

For Adults (18-50 years)

Adults in this age range may benefit most from Maritime Pine Bark’s support for athletic performance, stress management, and cardiovascular health. The extract can help maintain healthy blood pressure, support endurance during exercise, and protect against oxidative stress from environmental factors.

Recommended dosage for adults: 50-100 mg daily, divided into 2-3 doses

For Older Adults (50+ years)

As we age, Maritime Pine Bark becomes particularly valuable for cognitive support, joint health, and cardiovascular protection. Older adults may experience more pronounced benefits for memory, focus, and overall brain health, while also supporting healthy circulation and reducing age-related inflammation.

Recommended dosage for older adults: 100-150 mg daily, divided into 2-3 doses

Gender-Specific Benefits

For Women:

• Supports skin elasticity and hydration
• May help manage symptoms associated with menopause
• Supports cardiovascular health, which is especially important post-menopause
• May help reduce the appearance of melasma and hyperpigmentation

For Men:

• Supports healthy blood flow, which may benefit erectile function
• Assists with recovery after intense physical activity
• Supports prostate health through anti-inflammatory properties
• May help maintain cognitive performance during aging

For Specific Health Conditions

For those with cardiovascular concerns: 100-200 mg daily may provide optimal support for vascular health and blood pressure management.

For those with joint discomfort: 100-150 mg daily may help reduce inflammation and support joint mobility.

For those with cognitive concerns: 150 mg daily, preferably divided into three doses, may provide optimal brain support.

For those with skin conditions: 50-100 mg daily, combined with topical applications containing Maritime Pine Bark, may provide comprehensive skin support.

As with any supplement, it’s important to consult with a healthcare provider before beginning Maritime Pine Bark supplementation, especially for children, pregnant or nursing women, or individuals with existing health conditions.

Maritime Pine Bark Side Effects and Safety

Pycnogenol’s most commonly reported side effects include:

• Dizziness
• Vertigo
• Fatigue
• Gastrointestinal issues
• Nausea
• Irritability
• Headache
• Drowsiness

Maritime pine bark extract can also increase the risk of bleeding or chances of bruising if used with other medications that have similar effects.

That said, taking Pycnogenol is well-tolerated for up to 12 months without major adverse effects.

Summary

In conclusion, maritime pine bark extract, particularly in the form of Pycnogenol, is a powerful antioxidant supplement with a broad spectrum of potential health benefits.

Maritime Pine Bark is used in herbal medicine is backed by significant clinical research, highlighting its role in promoting cardiovascular health, managing osteoarthritis symptoms, and supporting overall well-being. 

Remember, as with any herbal supplement, proper dosage and consultation with a healthcare provider to ensure you’re safely incorporating Maritime Pine Bark extract products is vital.

FAQs

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2. Schoonees, Anel et al. “Pycnogenol® (extract of French maritime pine bark) for the treatment of chronic disorders.” The Cochrane database of systematic reviews ,4 CD008294. 18 Apr. 2012, doi:10.1002/14651858.CD008294.pub4↩
3. Tenenbaum, S et al. “An experimental comparison of Pycnogenol and methylphenidate in adults with Attention-Deficit/Hyperactivity Disorder (ADHD).” Journal of attention disorders vol. 6,2 (2002): 49-60. doi:10.1177/108705470200600201↩
4. Liu, Ximing et al. “Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.” Life sciences vol. 74,7 (2004): 855-62. doi:10.1016/j.lfs.2003.07.037↩
5. Zhang, Zheng et al. “Effect of Pycnogenol Supplementation on Blood Pressure: A Systematic Review and Meta-analysis.” Iranian journal of public health vol. 47,6 (2018): 779-787.↩
6. Valls, Rosa-M et al. “Effects of low molecular weight procyanidin rich extract from french maritime pine bark on cardiovascular disease risk factors in stage-1 hypertensive subjects: Randomized, double-blind, crossover, placebo-controlled intervention trial.” Phytomedicine : international journal of phytotherapy and phytopharmacology vol. 23,12 (2016): 1451-1461. doi:10.1016/j.phymed.2016.08.007↩
7. Errichi, B M et al. “Prevention of post thrombotic syndrome with Pycnogenol® in a twelve month study.” Panminerva medica vol. 53,3 Suppl 1 (2011): 21-7.↩
8. Heffernan, S M et al. “Mineral rich algae with pine bark improved pain, physical function and analgesic use in mild-knee joint osteoarthritis, compared to Glucosamine: A randomized controlled pilot trial.” Complementary therapies in medicine vol. 50 (2020): 102349. doi:10.1016/j.ctim.2020.102349↩
9. Simpson, Tamara et al. “Assessing the Efficacy and Mechanisms of Pycnogenol^® on Cognitive Aging From In Vitro Animal and Human Studies.” Frontiers in pharmacology vol. 10 694. 3 Jul. 2019, doi:10.3389/fphar.2019.00694↩