Phenylpiracetam Review: Dosage, Side Effects & Where to Buy

In this Phenylpiracetam review, we'll go over everything you need to know about this popular nootropic. We'll also discuss how Phenylpiracetam works in the brain, as well as the benefits, side effects, and where to buy it online.

Phenylpiracetam should be the first word that comes to mind if you are looking for nootropics to help boost your focus and endurance to tackle mental challenges.

Or if you want to improve your energy levels for better physical performance in sports.

Read this Phenylpiracetam review to learn more about the correct dosage, how to use it, how to stack it up, and much more!

Phenylpiracetam Review Summary

In summary, Phenylpiracetam is a potent nootropic supplement that can provide a variety of cognitive benefits. It is thought to work by increasing the neurotransmitter acetylcholine and modulating other important brain chemicals (dopamine and norepinephrine). Phenylpiracetam is also thought to improve blood flow and oxygen utilization in the brain, which may improve cognitive function even further.

If you want to improve your memory, learning, and focus, Phenylpiracetam might be worth a shot.

Pros:

  • Boosts brain function
  • Reduces dyslexia symptoms
  • Enhances memory and learning
  • Improves focus and attention
  • Relieves stress

Cons:

  • Some people may experience side effects like headaches

What is Phenylpiracetam?

phenylpiracetam chemical structure

Phenylpiracetam[1]“Fonturacetam.” National Center for Biotechnology Information. PubChem Compound Database, U.S. National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/132441. (also known as Fonturacetam and marketed as Phenotropil, Carphedon, and Nanotropil Novo) is a nootropic drug developed in Russia in 1983. It was created to assist Soviet cosmonauts in dealing with the stress of working in space. In Russia, the drug is now available on prescription.

phenylpiracetam review

Animal studies have revealed that phenylpiracetam may have a variety of benefits, including memory enhancement, anti-amnesia, antidepressant, and anticonvulsant properties[2]Bobkov, Iu G et al. “Farmakologicheskaia kharakteristika novogo fenil'nogo analoga piratsetama--4-fenilpiratsetama” [Pharmacological characteristics of a new phenyl analog of … Learn more.

Imagebuy phenylpiracetam
NamePhenylpiracetam
ClassNootropic
EffectsImproved attention and focus, improved cognitive function, better mood
Potential Side EffectsHeadache, irritability, brain fog, insomnia, depression
Half-Life3-5 hours
Common Dosage100-600 mg 3x daily
Content30 capsules x 100 mg
Price$54.99
Money Back Guarantee30 days
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What is Phenylpiracetam Hydrazine?

Phenylpiracetam Hydrazine

Phenylpiracetam hydrazide is a racetam that is similar to phenylpiracetam, but with the addition of a hydrazide group in place of the amide group. The compound was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as anticonvulsants.

The recommended phenylpiracetam dosage is 100-600 mg a day split into 2-3 servings for pure powder, while for the hydrazide equivalent, only 50mg to 100mg is required for similar effects. Many manufacturers sell pure phenylpiracetam powder to researchers, but they are unable to provide suggested serving sizes or dosages.

What is Phenylpiracetam Used for?

A few limited clinical studies have linked phenylpiracetam to improvement in encephalopathic disorders, including lesions of cerebral blood routes, traumatic brain injury, and certain kinds of glioma[3]Savchenko, A Iu et al. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 105,12 (2005): 22-6.. Phenylpiracetam reverses diazepam's depressive effects, promotes operant behavior, decreases post-rotational nystagmus, and prevents retrograde amnesia[4]Malykh, Andrei G, and M Reza Sadaie. “Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.” Drugs vol. 70,3 (2010): 287-312. … Learn more. Phenylpiracetam is administered as a stimulant or to increase stress and heat tolerance. Parkinson's disease treatment research includes phenylpiracetam.

Pilot-cosmonaut Aleksandr Serebrov detailed receiving and utilizing Phenylpiracetam during his 197-day mission onboard the Mir space station. "The medicine operates as the whole-body equalizer, combing, omitting impulsiveness and irritation," he said[5]“Фенотропил: Закономерное Лидерство.” Medi.ru, https://medi.ru/info/427/.. The Serbsky Center for Social and Forensic Psychiatry conducted clinical trials. The Serbsky Center, Moscow Institute of Psychiatry, and Russian Center of Vegetative Pathology have confirmed Phenylpiracetam's effectiveness, describing its effects as improving regional blood flow in ischemic regions of the brain, reducing depressive and anxiety disorders, increasing brain tissue's resistance to hypoxia and toxic effects, improving concentration and mental activity, and having a psychoactivating effect.

How does Phenylpiracetam Work in the Brain?

With an IC50 of 5.86 μM, phenylpiracetam binds to nicotinic acetylcholine receptors in the mouse brain cortex and elevates extracellular dopamine levels following treatment.[6]Firstova, Yu. Yu., et al. “The Effects of Scopolamine and the Nootropic Drug Phenotropil on Rat Brain Neurotransmitter Receptors during Testing of the Conditioned Passive Avoidance Task - … Learn more Phenylpiracetam may also serve as a noradrenaline reuptake inhibitor (NDRI). Experiments on Sprague-Dawley rats in a European patent for treating sleep disorders with Phenylpiracetam revealed a rise in extraterrestrial dopamine levels after dosing.[7]“EP2891491A1 - Use of (r)-Phenylpiracetam for the Treatment of Sleep Disorders.” Google Patents, Google, https://patents.google.com/patent/EP2891491A1.

What are the Benefits of Phenylpiracetam?

phenylpiracetam benefits

One of the most common benefits of phenylpiracetam is to boost energy and productivity. Many people also take it to improve their motivation and mental drive. It is also known to reduce anxiety before stressful situations. It can also help support endurance, greater exercise intensity, and neuromotor impulses.

Phenylpiracetam reduced the extent of neuralgic deficiency manifestations in Wistar rats with gravitational cerebral ischemia, preserved locomotor, research, and memory functions, increased survival rate, and favored local cerebral flow restoration after carotid artery occlusion more than piracetam.

In an animal study, d-amphetamine rats completed 150% more labor and ate 50% more non-preferred rat chow when administered 1 mg/kg amphetamine. Rats given 10 mg/kg Methylphenidate worked 170% harder and consumed the same amount of food, but rats given 100 mg/kg Phenylpiracetam worked 375% harder and ate 35% less non-preferred rat chow. In general, this suggests that Phenylpiracetam increases motivation and that its impact is substantially greater than that of methylphenidate or amphetamine.

While the exact mechanism of phenylpiracetam remains unknown, preliminary studies suggest that it may have neuroprotective and anti-amnesic effects. In animal studies, it was shown to improve motor coordination, memory, and motor functions in rats. Furthermore, it significantly increased the survival of epileptic test subjects, enhancing the cognitive functions of those animals. However, more human studies are necessary for further research.

What is the Dosage of Phenylpiracetam?

phenylpiracetam dosage

Single oral doses usually range from 100 to 250 mg. The maximum daily dose is 600 mg. Phenylpiracetam should be taken once daily in the morning, with the larger doses being divided into two or three doses during the day. The duration of the treatment course can range from two weeks to three months. It can be repeated within a month for maintenance treatment.

If you prefer maximum stimulating effects over a full treatment cycle, keep in mind that Phenylpiracetam quickly builds tolerance. You may require twice as much on the second day and will most likely not notice the subjective effects on the third day. As a result, if you want to experience its full range of effects, it's best to take it no more than three times per week.

What are the Side Effects of Phenylpiracetam?

phenylpiracetam side effects

Phenylpiracetam has a low potential for abuse and is not dangerous when taken at the recommended dosage. However, some side effects of phenylpiracetam are possible, including irritability, headache, and drowsiness.

Although phenylpiracetam is an antipsychotic,[8]Akhapkina, V I, and R V Akhapkin. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 113,7 (2013): 42-6. it can cause uncomfortable and serious side effects in some patients, including anxiety, insomnia, and sensory overload. You may need to reduce the dosage to prevent these side effects. It has also been associated with heightened anger, aggressiveness, and suicidal thoughts. It is not yet known how long it takes to take phenylpiracetam before you notice any adverse effects.

Phenylpiracetam Reviews & Experiences Shared on Reddit

phenylpiracetam reddit

If you look at the reported experiences of Reddit users, you can get a better understanding of how Phenylpiracetam works for cognitive enhancement:

"Ido n'tKnowButchy Instd" reported:

"The best way to take Phenyl Piracetam would be on a cycle, maybe a few days a week, then a week or two layoffs. Stack it with Alpha GPC, Sulbutiamine, or another Nootropic/Racetam. Phenylpiracetam is equally as effective if it is only used on an as-needed basis, to help study for an important test or when you want a very focused and intense workout."

"Spitzze" reported:

"Today, I took 150 mg of Phenylpiracetam with a 100 mg/200 mg caffeine/theanine capsule, and I can't say what I'm feeling right now is a placebo. Sort of like a Vyvanse lite without the robotic emotion dulling. Definitely enjoying this combo since it's making my calculus class easier by a long shot! Would definitely recommend it for people with attention problems."

What are the Best Phenylpiracetam Stacks?

phenylpiracetam stacks

There are many nootropic supplements that contain phenylpiracetam, but how do you find the best Phenylpiracetam stack for yourself? Everyone is different, and some of these may not be right for you. A beginner can use a stack that has Alpha-GPC, a nootropic that can help them eliminate Phenylpiracetam's side effects.

  • Alpha-GPC. L-Alpha glycerylphosphorylcholine is also known as Alpha GPC. It is a natural cholinergic with neuroprotective and cognitive enhancing properties. It is found naturally, but it is also available as a supplement to help with fatigue.
  • CDP-Choline. Choline is a brain nutrient that is obtained in small amounts from meat and fish and is required for many brain functions. Stacking phenylpiracetam with CDP-choline enhances the effects because choline has similareffects.
  • Sulbutiamine. Sulbutiamine is a synthetic vitamin B1 derivative that improves sharpness, alertness, motivation, and reduces anxiety. It easily crosses the blood-brain barrier to stimulate neurotransmitters that improve your health. It also improves your memory, decision-making abilities, learning abilities, and problem-solving abilities. Stacking phenylpiracetam with sulbutiamine improves feelings significantly.

Where to Buy Phenylpiracetam Powder & Capsules?

phenylpiracetam buy

If you're wondering where you can buy Phenylpiracetam, it's available at a number of online stores, but not all of them are reliable.

We recommend that you buy the original Nanotropil from Russia or the generic alternative.

Frequently Asked Questions (FAQ)

Your questions answered:

Is Phenylpiracetam safe?

Despite being safe for most people, phenylpiracetam can cause mild side effects, including headaches. This drug's excess acetylcholine at receptor sites causes these symptoms. To ensure the brain has enough choline, take it with Alpha GPC, a precursor of acetylcholine. Phenylpiracetam is not FDA-approved, but a prescription drug in Russia.

How long does Phenylpiracetam last?

The elimination half-life of Phenylpiracetam is 3-5 hours. Its effects can last about 6-10 hours depending on the dose and your individual metabolism.

How does Phenylpiracetam make you feel?

Phenylpiracetam binds to nicotinic cholinergic receptors and may increase NMDA-glutamate receptors. It's quickly absorbed in the digestive tract and distributed to the brain. In rats and mice, it reduces depressive symptoms and increases motivation. It makes you feel focused, motivated, and energized.

Is Phenylpiracetam a stimulant?

Phenylpiracetam is a stimulant. It inhibits dopamine and noradrenaline reuptake, resulting in stimulating effects.

Conclusion

Phenylpiracetam appears to be a potent drug with promising results. However, as with any supplement, there are some risks. The trick is to administer the appropriate amount and stack. And, as previously stated, it is preferable to take it only when necessary rather than on a daily basis.

According to phenylpiracetam reviews, if taken responsibly, in the recommended dosage, cycling, and stacking, it can help improve your focus and energy levels, which can be beneficial both mentally and physically.

References

References
1“Fonturacetam.” National Center for Biotechnology Information. PubChem Compound Database, U.S. National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/132441.
2Bobkov, Iu G et al. “Farmakologicheskaia kharakteristika novogo fenil'nogo analoga piratsetama--4-fenilpiratsetama” [Pharmacological characteristics of a new phenyl analog of piracetam--4-phenylpiracetam]. Biulleten' eksperimental'noi biologii i meditsiny vol. 95,4 (1983): 50-3.
3Savchenko, A Iu et al. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 105,12 (2005): 22-6.
4Malykh, Andrei G, and M Reza Sadaie. “Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.” Drugs vol. 70,3 (2010): 287-312. doi:10.2165/11319230-000000000-00000
5“Фенотропил: Закономерное Лидерство.” Medi.ru, https://medi.ru/info/427/.
6Firstova, Yu. Yu., et al. “The Effects of Scopolamine and the Nootropic Drug Phenotropil on Rat Brain Neurotransmitter Receptors during Testing of the Conditioned Passive Avoidance Task - Neurochemical Journal.” SpringerLink, SP MAIK Nauka/Interperiodica, 8 June 2011, https://link.springer.com/article/10.1134/S1819712411020048.
7“EP2891491A1 - Use of (r)-Phenylpiracetam for the Treatment of Sleep Disorders.” Google Patents, Google, https://patents.google.com/patent/EP2891491A1.
8Akhapkina, V I, and R V Akhapkin. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 113,7 (2013): 42-6.
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