14 Best Nootropics for Energy (Get Energized)

In this article, we'll take a deep dive into the 14 best nootropics on the market for energy. We will look at the benefits of each nootropic, how they work in the brain, and what the science says.

We've all been there – feeling lethargic, low on energy, and completely unmotivated.

What if you could just take a pill that would make you instantly energetic and alert?

Wouldn't that be great?

Well, as it turns out, there are quite a few nootropics that can provide this type of energy boost.

So if you're looking for the best nootropics to get energized without relying sorely on caffeine this article is for you!

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Nootropics can be natural or synthetic. Despite being two different things, they both have the components to help you enhance your mind skills, improve brain functions, and optimize your energy.

Here are some of the best smart drugs that help you boost brain energy and increase your brain function.

According to both scientific evidence and customer reviews, the 14 best nootropics for energy are:

1. Vyvamind

Often described as an alternative to Adderall by its users, Vyvamind is the best pre-made nootropic stack for energy.

Although Vyvamind doesn't contain many ingredients, the ones it does contain are clinically proven to be effective and work in perfect synergy to promote focus and energy throughout the day.

2. NooCube

NooCube is a cognitive supplement that helps your brain focus, retain information, and boost your memory.

It provides a synergistic blend of vitamins, minerals, and other essential building materials for a healthy, well-functioning brain.

NooCube is a proprietary blend of natural ingredients such as Alpha GPC, Huperzine A, Cat's Claw, Bacopa monnieri, oat straw, L-theanine and L-tyrosine.

It does not contain caffeine, unlike many other nootropics, but still gives you a clean boost in energy.

3. Mind Lab Pro

Mind Lab Pro is marketed as the world's first universal nootropic and is intended to boost all aspects of cognitive function.

It contains 11 clinically-proven brain-boosting ingredients that will support memory, focus, concentration, mental clarity, energy, and learning.

Mind Lab Pro does not contain caffeine, but it does include ingredients that complement it, improving its effect significantly. For a smooth lift, take 2 capsules with your morning coffee. Clean, calm, jitter-free mental energy is needed to power up for the day.

4. Citicoline

Citicoline is a nootropic compound that enhances focus, attention, and overall mental performance. This supplement also raises dopamine and acetylcholine levels associated with all executive brain functions like memory and learning.

Citicoline is usually used as a foundational supplement for the nootropics stack due to its safe interactions with other memory-enhancing drugs. It is also easily absorbed by the body and has high bioavailability.

Citicoline is also a research-backed nootropic. A clinical study shows that supplementation with a higher dosage of Citicoline provides a significant improvement in older adults’ mental processing and cognitive functions [R].

5. Rhodiola Rosea

Rhodiola Rosea is an herbal nootropic known to fight different kinds of stress. Russian, Chinese, and Scandinavian traditional medicines commonly use this herb to combat fatigue or burnout.

Research shows that Rhodiola Rosea has physical and mental benefits as a powerful adaptogen that prevents the negative effects of stress [R]. Aside from this, Rhodiola also improves mood, restores energy, and protects the brain from toxin damage.

It was also shown that Rhodiola is effective in combating chronic fatigue produced by repetitive low-intensity movements or prolonged high stress [R]. While this may not be as effective for professional athletes, Rhodiola may help energize both mind and body after a grueling day.

6. Caffeine

Caffeine is probably the best natural nootropic that you can get your hands on. This nootropic is often used in various everyday beverages such as coffee, tea, and energy drinks.

According to various studies, this psychoactive drug improves focus, mood, and alertness [R]. Caffeine also blocks adenosine receptors in the brain, which helps your body feel less tired and more alert.

Aside from being a source of energy, Caffeine also gives you faster reaction times. The physical and mental energy you get from a caffeine supplement will be beneficial as you review for an exam or stay awake to be more productive.

7. Acetyl-L-Carnitine

Acetyl-L-Carnitine is one powerful nootropic that not only enhances cognition but also fights physical and mental fatigue. ACLAR also combats aging effects by improving the brain function of people with age-related cognitive decline.

ACLAR also crosses the blood-brain-barrier easily and works within the brain cells by maintaining cellular integrity. This naturally-occurring nutrient is also a precursor of acetylcholine, a neurotransmitter associated with learning.

8. Curcumin

Curcumin is a natural nootropic that is an active component of turmeric which is a powerful antioxidant.

This turmeric component shows potential neuroprotective efficacy as an anti-inflammatory and antioxidant, which can protect your body against free radicals and inflammation [R]. Taking this brain-boosting supplement could also support your cognitive function and promote a healthy mood.

Curcumin could also boost neurogenesis, the production of brain cells essential for learning. It also stimulates neurotransmitters such as serotonin associated with good mood, cognition, and focus.

9. L-Theanine

L-Theanine, which you can find in green tea, is one amino acid that modulates brain functions. It supports the production of certain brain chemicals such as dopamine and serotonin.

Theanine influences your mood, emotion, sleep, and how your body deals with the causes of stress. This compound also aids in producing alpha waves in the brain, which leads to restful alertness.

Users usually combine (also called stacking) L-Theanine with caffeine as it balances the substance’s jittery effects through its calming benefits.

A study also shows how taking L-Theanine with caffeine and L-Tyrosine may enhance energy production in athletes whose sports require fast body movements [R].

10. Phenylpiracetam

Phenylpiracetam is a nootropic from the Racetam family. It is a derivative of Piracetam, another nootropic compound. This nootropic’s only difference with Piracetam is the added phenyl ring, the same structure as amphetamines.

Aside from its brain-boosting effects and improvement in energy levels and well-being, Phenylpiracetam also has anxiolytic properties that improve mood and reduce anxiety levels when in a high-stress environment.

Russian cosmonauts use this nootropic to combat stress when working in space without affecting memory and cognitive performance.

11. Modafinil

Modafinil is a powerful stimulant for wakefulness, a drug developed to treat narcolepsy and other sleep disorders.

Aside from inducing wakefulness and alertness, it also has a list of brain-boosting benefits like enhancing focus and memory, stimulating the mind, increasing motivation, productivity and energy. It has also been shown to improve mood even for people who are in a sleep-deprived state [R].

Modafinil also helps in reducing fatigue perception and extending the time to exhaustion during high-intensity exercise.

12. Noopept

Noopept is a fast-acting nootropic that contains both stimulant and anxiolytic properties. This supplement is also known for its memory-enhancing benefits and as a treatment for cognitive impairments.

Since we can use it as a treatment for cognitive decline, most research on Noopept is done on people with impairments like neurodegeneration, stroke, and other brain diseases [R].

Meaning to say, we still don’t have any reported studies on Noopept’s effect on healthy humans. However, since it helps boost mind functions and enhance motivation, the reports from users are positive.

13. Oxiracetam

Oxiracetam is a potent nootropic that enhances a wide range of mental processes like long-term memory, focus, and verbal fluency. It is a synthetic derivative of piracetam, a known potent nootropic.

Aside from the brain-enhancing benefits, Oxiracetam also acts as a mild psychostimulant that may enhance mental energy and motivation. This may offer you increased endurance to perform various tasks without feeling tired quickly. In an animal study, this nootropic shows help inhibit sleep and promote alertness by enhancing blood flow in the brain, thus improving energy metabolism [R].

14. Sulbutiamine

Sulbutiamine is a derivative of Vitamin B1 or Thiamine. A lab in Japan developed this synthetic derivative to treat chronic fatigue and beriberi, a nervous disorder caused by a B1 deficiency.

While Sulbutiamine treats fatigue and thiamine deficiency, it may also benefit healthy people as it boosts memory and improves mental performance by promoting brain chemicals like acetylcholine.

Sulbutiamine may also boost your energy and mood by increasing glutamate levels.

How Nootropics Improve Energy

Nootropics are a type of cognitive enhancement that has become increasingly popular in recent years.

Often known as "smart drugs," nootropics can help to improve focus, memory, and other cognitive functions.

They are also becoming more recognized for their ability to boost energy levels.

While the exact mechanisms behind this effect are not fully understood, it is believed that nootropics work by increasing the availability of neurotransmitters like dopamine and serotonin.

This increase can lead to improved focus and concentration, as well as increased motivation and energy levels.

In addition, nootropics may also help to reduce stress and anxiety, which can further improve energy levels.

As more research is conducted on the potential benefits of nootropics, it is becoming clear that they have the potential to provide a real boost of energy when needed [R].

how nootropics improve short term memory

If you're looking for an all-in-one nootropic blend that will energize you, Mind Lab Pro is our top pick.

Mind Lab Pro is a comprehensive nootropic supplement that contains 11 clinically-proven ingredients, including L-Tyrosine and Rhodiola Rosea.

These ingredients work together to provide a powerful boost of energy that can help you to get through even the most challenging tasks.

Nootropics Side Effects

Nootropics possess various cognitive benefits that help people achieve peak mental performance. While this may focus on the positive side, nootropics also have a fair share of adverse side effects.

nootropics side effects

Since we have different body chemistry, the ingredients in the supplements may cause negative interactions with our bodies. This is also true with mindlessly consuming nootropic stacks.

Some of the side effects that you may experience from taking nootropics are:

  • Headaches
  • Nausea
  • Stomach issues
  • Insomnia
  • Dizziness

The FDA does not regulate these supplements, unlike prescription drugs like Adderall. You must look for reputable brands with safe ingredients.

Consult a doctor first before taking nootropics, especially if you take medications contraindicated by the ingredients.


Nootropics are not simply brain enhancers that eliminate brain fog, improve focus, and other mind-boosting benefits. They also have promising benefits in terms of energy and motivation.

Since there are various nootropic supplements for energy, it is essential to know which cognitive enhancers are the best and most effective for you.

Please note that this article is only a guide and does not provide medical advice, diagnosis, or treatment. To be safe, consult your physicians first.