8 Great Nootropics for Sleep & Insomnia in 2024

An overview of the best nootropics for enhancing sleep quality and combating insomnia.

Are you having trouble sleeping?

Are you looking for a natural way to improve your sleep quality?

If so, then look no further!

In this article, we’ll be discussing the best nootropics to help you get a good night’s rest.

Read on to learn more about these powerful supplements and how they can help you sleep like a baby.

Nootropics Good for Sleep

  • Nooceptin — Best to improve overall cognitive function
  • Lemon Balm — Best herbal nootropic for promoting a calm state of mind
  • GABA — Best to regulate sleep-wake cycle
  • Ashwagandha — Great to help the body cope with stress
  • Bacopa Monnieri — Great for enhancing synaptic plasticity
  • Phenibut — Best to enhance GABA levels
  • L-Tryptophan — Great to help regulate mood, sleep and appetite
  • L-Theanine — Great for improving mental and physical health

How to Choose the Most Effective Nootropics for Sleep?

Selecting the ideal nootropics for sleep involves considering various factors that influence their efficacy and safety. By understanding these criteria, you can make an informed decision to enhance your sleep quality.

FactorDescriptionWhy It’s Important
Ingredient QualityThe purity and source of the nootropics in the supplement.Ensures effectiveness and safety.
DosageThe amount of each ingredient per serving.To match clinically effective levels.
Side Effect ProfilePotential adverse reactions or interactions with other substances.Minimizes health risks.
Mechanism of ActionHow the nootropic works in the brain to promote sleep.Directly relates to effectiveness.
User ReviewsFeedback from individuals who have used the nootropics for sleep.Provides real-world efficacy data.
  • Ingredient Quality: Premium ingredients typically yield better results. It’s important to look for supplements that use high-quality, pure ingredients to avoid contaminants that could disrupt sleep.
  • Dosage: Correct dosing is crucial for any supplement. A nootropic must be dosed appropriately to be effective without causing adverse effects, aligning with evidence from scientific research.
  • Side Effect Profile: It’s vital to understand any potential side effects. A nootropic with minimal side effects is preferable for long-term use, especially for something as critical as sleep.
  • Mechanism of Action: Knowing how a nootropic promotes sleep can help you determine if it’s the right fit for your specific sleep issues, whether it’s reducing anxiety or modulating neurotransmitter levels.
  • User Reviews: Real-life experiences offer insight into the effectiveness and potential issues with nootropics, adding an extra layer of information beyond clinical studies.

Great Nootropics for Sleep

According to our in-depth research and testing, the best nootropics for sleep are:

1. Nooceptin

Nooceptin contains a blend of ingredients designed to help promote better sleep. The ingredients, such as L-theanine, Rhodiola Rosea extract, and Citicoline, have been scientifically proven to reduce stress and anxiety levels, which can improve the quality of sleep.

Nooceptin supplement bottle

Additionally, Nooceptin’s unique blend of nootropics helps to increase blood flow to the brain, which can help the brain to relax and prepare for sleep. This can help improve sleep quality and duration, making Nooceptin an ideal choice for those seeking a better night’s sleep.

2. Lemon Balm

Lemon balm is a herbal remedy that has been used for centuries to promote relaxation and restful sleep. It is a member of the mint family, and it contains a variety of compounds that can help reduce anxiety, stress, and insomnia. It can be consumed in various forms such as tea, tincture, and capsules. Studies have shown that lemon balm can help induce sleep, reduce restlessness, and improve sleep quality.

Additionally, this herb has been found to be effective in reducing symptoms of anxiety, depression, and other mental health issues. Taking lemon balm can help you relax and sleep better, and it has few side effects when taken in recommended doses.


GABA is a neurotransmitter which helps to reduce arousal levels in the brain. It plays a key role in regulating the body’s sleep-wake cycle by calming the brain and helping to induce sleep. GABA works by inhibiting nerve transmission in the brain, which in turn slows down brain activity and helps the body relax. This helps to reduce stress and anxiety, allowing the body to wind down and prepare for restful sleep.

4. Ashwagandha

Ashwagandha is an adaptogen that has been used in Ayurvedic medicine for centuries. It helps to reduce stress and anxiety, which can be major roadblocks to a good night’s sleep. The herb also helps to regulate cortisol levels, which can have an effect on your ability to fall asleep and stay asleep.

Additionally, ashwagandha has been known to increase GABA levels, which can help to induce a state of relaxation so you can drift off to sleep more easily.

5. Bacopa Monnieri

Bacopa Monnieri is another natural nootropic that has been used for centuries to improve mental performance, focus, and memory. It is also known to be effective in improving the quality of sleep. Research suggests that Bacopa Monnieri increases the production of melatonin, the hormone that helps regulate sleep cycles. It also helps to reduce anxiety and stress, both of which can contribute to insomnia.

Additionally, Bacopa Monnieri is believed to reduce the time it takes to fall asleep and may also help to improve the duration and quality of sleep.

6. Phenibut

Phenibut is a nootropic that is also known as a GABAergic compound or mood supplement. It is commonly used to treat conditions such as insomnia, restless legs syndrome, jet lag, and sleep disorders. It works by increasing the neurotransmitter GABA which helps to relax the body and induce sleep. Phenibut can also be used to reduce anxiety and stress, making it an effective sleep aid for those who suffer from sleep disturbances due to stress and anxiety.

While Phenibut is generally considered safe, it can have some side effects such as dizziness, nausea, and headaches. It is important to note that Phenibut should be taken with caution and only used under the guidance of a healthcare professional.

7. L-Tryptophan

L-Tryptophan is an essential amino acid that plays an important role in improving sleep quality. It is one of the most common nootropic supplements used for sleep. It helps to increase serotonin levels, which is required to make the sleep hormone melatonin. Taking a supplement containing L-Tryptophan may also help to reduce feelings of anxiety, which can be beneficial for those with insomnia.

Furthermore, it can reduce symptoms of depression, which can also lead to better sleep. As with any supplement, it is important to talk to your doctor before taking L-Tryptophan to make sure it is the right choice for you.

8. L-Theanine

L-Theanine is an amino acid found in tea leaves and is known to have calming effects. It helps to reduce stress and anxiety, which can be a major factor in poor quality of sleep. Theanine has been shown to improve sleep quality and reduce fatigue. It also helps to prevent morning grogginess and can be taken as part of a daily supplement regimen for better sleep.

L-Theanine can also be used in combination with other natural sleep aids such as melatonin, which can help improve sleep quality and duration. Taking L-Theanine can also help to reduce nightmares, making it a great choice for those who suffer from sleep disturbances.

What to Consider Before Buying Nootropics for Sleep?

Before you invest in a nootropic for sleep, it’s essential to weigh certain considerations. These factors will guide you to a product that not only helps you sleep but also aligns with your health goals and lifestyle.

1. Compatibility with Current Health Conditions

Before adding any supplement to your routine, consider how it might interact with any existing health conditions you may have. Certain nootropics may exacerbate underlying issues or interact negatively with other medications or supplements you are taking.

2. Long-Term Use and Tolerance

Evaluate whether a nootropic is suitable for long-term use and if there’s a risk of developing tolerance. Some sleep aids might lose effectiveness over time or require higher doses, which is not ideal for sustained use.

3. Lifestyle and Sleep Hygiene

Consider how a nootropic fits into your overall lifestyle and sleep practices. No supplement can replace good sleep hygiene, such as maintaining a regular sleep schedule, creating a conducive sleep environment, and managing stress.

4. Expected Outcomes and Measurement of Success

Have clear expectations of what you want to achieve with the nootropic and think about how you will measure its success. Are you looking to shorten the time it takes to fall asleep, enhance sleep quality, or regulate your sleep-wake cycle?

5. Cost and Budget Alignment

Factor in the cost of the nootropic and if it aligns with your budget, especially if it’s something you’ll be taking regularly. A more expensive product might not always be the most effective one, so consider the cost-to-benefit ratio.

How We Picked Nootropics for Improved Sleep

We employed a comprehensive review process to determine the best nootropics for sleep improvement. Factors such as effectiveness, ingredients, brand reputation, transparency, production method, user feedback, price, and value were taken into account. By evaluating these aspects, we compiled a reliable and well-rounded list of the top sleep-promoting nootropics.


We studied clinical trials and user experiences to measure sleep quality improvement, concentrating on sleep onset, duration, and overall restorative effects.


We carefully examined each formula, emphasizing evidence-based, natural, and high-quality ingredients that enhance sleep quality.

Scientific Evidence

We consulted peer-reviewed studies and meta-analyses to confirm the effectiveness of essential ingredients in promoting restful sleep.


We evaluated the ideal dosages and ingredient ratios, ensuring they correspond with established research for maximum sleep benefits.


We assessed the safety of each ingredient, considering potential side effects and interactions, and confirming adherence to regulatory guidelines. Preference was given to FDA-approved ingredients.

Brand Reputation

We appraised the credibility and trustworthiness of brands through customer reviews, expert recommendations, and company history.

Product Transparency

We valued full ingredient disclosure, including sources and concentrations, promoting well-informed consumer decision-making.

Manufacturing Process

We inspected manufacturing standards, prioritizing products created in certified facilities and adhering to Good Manufacturing Practices (GMP).

User Reviews

We analyzed genuine customer feedback, giving importance to testimonials that describe sleep quality improvement and overall restfulness.


We compared product prices, ensuring they were competitive and proportionate to the quality and efficacy of the sleep nootropic.


We evaluated overall value, considering the balance of price, quality, and effectiveness to guarantee optimal return on investment.

Nootropics for Sleep in Summary

Nootropics can be a great way to help you get a good night’s sleep, but there are both pros and cons to consider. On the one hand, nootropics such as NooCube Sleep Upgrade can provide a natural and safe way to improve your sleep, without the risks and side effects associated with sleeping medications. Additionally, some nootropics can even help improve your cognitive function the next day, as well as provide calming and relaxing effects.

On the other hand, it is important to be aware of the potential side effects of using nootropics for sleep. While the majority of nootropics are safe, some may cause mild side effects, such as nausea and headaches. Additionally, long-term use of some nootropics can lead to tolerance, meaning that it may become less effective over time.

For these reasons, it is important to do your research and consult with your doctor before taking any nootropics for sleep. This will ensure that you can get the most benefits out of taking nootropics and reduce the risk of any potential negative side effects. With the right nootropics and proper dosage, you can get the restful sleep you need and enjoy the many benefits of improved cognitive function the next day.

FAQs About Nootropics for Sleep

Can nootropics help with sleep?

Nootropics may help improve the quality of your sleep and make it easier for you to both fall asleep and stay asleep. Some nootropics have been suggested to help improve cognitive performance in sleep deprived study subjects. Supplements like L-tyrosine and Ashwagandha may aid in enhancing cognitive performance, while Valerian root can be used to reduce stress and anxiety which can contribute to better sleep.

Are nootropics safe to use for sleep?

Yes, some nootropics are safe to use for sleep. Tryptophan is known to be a much safer and more efficient option for naturally raising serotonin and melatonin. Ashwagandha is usually considered safe and allowed, and early proof implies it has a large beneficial effect on sleep. However, there is still not enough evidence from large, controlled studies regarding the effects of nootropics on the brain.

How do nootropics affect sleep?

Norepinephrine production can lead to a lack of REM sleep, so nootropics that block the production of this neurotransmitter may be helpful. Some nootropics like ashwagandha and tulsi can enhance sleep quality by permitting the brain to perform better and release stress-induced neurotransmitters. However, some nootropics may make it harder to fall asleep and cause insomnia.

Can I take nootropics with other sleep aids or medications?

Certain drug classes may interact with nootropics, such as prescription nootropics used to treat conditions like ADHD and dementia. Natural sleep aids and the appropriate nootropics may be your best option for furthering brain recovery and cognitive performance if you are looking to boost focus and attention.

Jacob Kovacs is a cognitive neuroscientist and author at WholisticResearch, specializing in nootropics and neuroactive peptides. His expertise in neuroscience and psychopharmacology bridges cognitive science with drug development. Kovacs’ work focuses on enhancing cognitive functions and brain health through innovative, efficient neuroactive compounds that overcome traditional pharmacokinetic challenges. His contributions are pivotal in advancing the understanding and treatment of neurological diseases.