Centrophenoxine: Review of Nootropic Benefits, Uses, & Side Effects
In this Centrophenoxine review, we'll take an in-depth look at what this popular nootropic is. We'll also go over how Centrophenoxine works in the brain, information about its benefits, side effects, and popular uses.
What is Centrophenoxine?

Centrophenoxine, also known as meclofenoxate, is a cholinergic nootropic used as a dietary supplement to alleviate cognitive symptoms of dementia.(1) It is used to treat alcoholism and other conditions in China and elsewhere.
As a nootropic, Centrophenoxine increases glucose and oxygen uptake in the brain, increases acetylcholine levels,(2) protects neurons from oxidative damage, and improves overall cognitive performance.
It is a better absorbed transporter of DMAE (Dimethylaminoethanol)(3) into the brain compared to other cholinergic agents. It is a combination of DMAE and pCPA (parachlorphenoxyacetic acid).
Centrophenoxine's nootropic effects have been studied extensively in research studies and clinical trials, making it a popular choice for those seeking cognitive enhancement.
Benefits
Centrophenoxine has a variety of potential benefits that make it a popular nootropic supplement. It has been shown to improve memory, cognition, and overall brain health, making it a great choice for those looking to give their brain the edge. Furthermore, its anti-aging properties may help to stave off age-related cognitive decline. For those suffering from Alzheimer's disease, centrophenoxine could potentially offer some relief from the symptoms.

It also appears to be safe and well-tolerated with few side effects or potential interactions with other medications. Since it is relatively affordable and easily obtainable, centrophenoxine is an attractive option for those looking to boost their mental performance.
Uses
Centrophenoxine is also used for cognitive enhancement, specifically to improve memory and focus. Studies have shown that it increases the uptake of glucose and oxygen in the brain, which is essential for energy production. It is also believed to increase the production of RNA and protein, both of which are involved in the formation of new memories.

Centrophenoxine has also been used to treat Alzheimer’s disease in some cases. It has also been shown to help prevent age-related cognitive decline.
Cognitive Enhancement
Centrophenoxine has been studied for its potential cognitive-enhancing benefits. Studies have found that it can improve memory performance in both healthy individuals and those with dementia. It is also thought to increase choline levels in the brain, which may improve the synthesis of acetylcholine, a neurotransmitter linked to learning and memory.
While there is limited evidence that centrophenoxine can cross the blood-brain barrier, it is still believed to be an effective nootropic compound that could potentially improve cognitive function.
Treatment for Alzheimer's Disease
Centrophenoxine has been studied as a potential treatment option for Alzheimer's disease and other degenerative brain disorders. It is thought to help improve cognitive function in those with dementia and Alzheimer's, by restoring the altered levels of acetylcholine, a neurotransmitter involved in memory and learning.
Studies have also suggested that Centrophenoxine can help reduce oxidant damage to the brain,(4) which can contribute to the development of dementia.
Furthermore, it has been shown to improve the activity of antioxidant enzymes in the brain, which helps protect against further damage.
Prevention of Age-Related Cognitive Decline
Centrophenoxine has been studied and found to be effective in preventing age-related cognitive decline. It helps boost cognition and memory, while also reversing neuronal decay. The cholinergic neurotransmitter system is believed to play a role in cognitive decline, and centrophenoxine helps to improve the altered short-term memory and cognitive performance that results from aluminium exposure.
Furthermore, regular intake of this nootropic can help reduce mental deterioration. This makes centrophenoxine an effective supplement for those looking to prevent age-related cognitive decline.
Side Effects
Centrophenoxine is generally well tolerated, but it can cause some mild side effects. The most commonly reported side effects are nausea, headache, dizziness, gastrointestinal issues, and increased blood pressure.

People with existing convulsive disorders such as epilepsy and severely high blood pressure should talk to their doctor before taking centrophenoxine as it may worsen their condition.
Potential Interactions with Medications
When it comes to interactions with medications, it is important to be aware that certain drugs such as anticholinergics may interact with Centrophenoxine. As a result, it is always advised to consult with your doctor or a qualified healthcare professional prior to taking Centrophenoxine supplements.
It is also important to note that the use of Centrophenoxine in combination with other cognitive enhancers or drugs may increase the risk of side effects.
Potential Allergies and Reactions
When it comes to potential allergies and reactions to centrophenoxine, users should be aware of any pre-existing conditions they may have. Those with asthma or allergies should use caution when taking any new supplement, including centrophenoxine.
While no major allergic reactions have been reported in the clinical trials, it is still important to be aware of your own individual sensitivities.
Conclusion
In conclusion, Centrophenoxine is a nootropic drug that has shown potential in treating a variety of conditions. It has been used to improve cognition, treat Alzheimer’s disease, and prevent age-related cognitive decline.
While it has many benefits, there are also some risks associated with its use. Centrophenoxine may interact with certain medications and cause allergic reactions or other side effects in some people.
It is important to discuss the use of Centrophenoxine with a doctor or pharmacist to determine if it is the right treatment for you.
FAQs
How long does it take for centrophenoxine to start working?
Centrophenoxine can start working quickly and temporarily enhance acetylcholinesterase in certain regions of the brain, within as few as a few minutes. Nevertheless, for more long-term effects, it should be taken for a month or longer.
Is centrophenoxine safe to use in the long term?
Centrophenoxine is non-toxic and is generally considered safe to use in the long term. Studies have shown that, when taken for an acute period (high doses for a month), it can be effective in reversing some of the signs of aging, particularly waste product buildup in the brain. Prolonged administration of centrophenoxine has also been shown to lead to significant reductions in lipofuscin in healthy elderly animals.
What is the recommended dosage of centrophenoxine?
The recommended dosage of centrophenoxine is typically between 250-2,000 mg a day, taken in two divided doses. This range is considered both safe and effective for most healthy adults. Clinical trials found that doses of 600 to 2,000 mg/day were the most effective for achieving neuronal protection and neurological enhancement.
Where can I buy centrophenoxine?
Centrophenoxine can be purchased from a range of online retailers. The best source to buy from is Science.bio. Amazon offers Centrophenoxine capsules 500mg with fast delivery. Nootropics Depot is another reliable source for high quality Centrophenoxine capsules, and Pure Nootropics supplies Centrophenoxine capsules that support improved cognition, memory and cellular health. eBay also has a plentiful selection of centrophenoxine products with free shipping on many items.
How should I store centrophenoxine?
Centrophenoxine should be stored in a cool, dark and dry place. If possible, refrigeration is recommended for optimal preservation once the product is opened. Centrophenoxine will begin to degrade if not kept cool, so storing it in the refrigerator is recommended to ensure its effectiveness.
Centrophenoxine

Do you want to improve your memory and concentration levels? If yes, Centrophenoxine should prove to help you here. Read this review to find out more.
4.8