The Best Natural Dopamine Supplements in 2023 Reviewed

Updated on January 1, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

The best dopamine supplements to improve cognition and well-being. From individual ingredients to FDA-approved stacks, we looked at the best natural dopamine supplements that increase dopamine production and influence its release in the brain.

Do you want to be more optimistic, motivated, and happier?

The solution you are looking for might be increasing dopamine.

It’s not unnatural to increase dopamine through high dopamine producing activities, or even dopamine supplements. Dopamine, a neurotransmitter and chemical release in the brain, is a neurological process that we can influence naturally with little to no known side effects.

Best Natural Dopamine Supplements (= Significant Increase)

In fact, making sure to maintain an increased level of dopamine - called the “motivational hormone” - is one of the easiest ways we can improve our overall mental well-being, cognitive capacity, and ability to handle day-to-day tasks effectively.

And while we can go out of our way to exercise more, eat healthier, sleep better, and be more outgoing, we can also take natural dopamine supplements and nootropics that help encourage this process.

After all, supplements, while optional, are there to help.

The Benefits of Dopamine

Why should you take dopamine supplements?

To answer this question, we should look at and learn to recognize the symptoms of dopamine deficiency.

Low dopamine levels can result in low motivation, poor concentration, reduced focus, short attention span, brain fog, brain toxins, heightened stress levels, and difficulty to think quickly and solve problems.

Physical symptoms can be fatigue, muscle aches, muscle stiffness, cramps, and constipation.

And while dopamine deficiency is not a direct cause of mental illness or disorders, the symptoms themselves can in fact accumulate, aggravate one another, eventually leading to depression, anxiety, anorexia, and insomnia.

High Levels of Dopamine

High levels of dopamine, on the other hand, improve our cognition in more than a few ways and cause us to feel more motivated, more content, and more excited about life in general.

What’s special about dopamine is that the improved mood it provides us directly feeds our brainpower, and vice versa, with the ability to provide an endless cycle of enhanced mood and increased productivity.

To be specific, dopamine, the “feel-good”, “motivational” hormone, is necessary for us to maintain for better concentration and focus, improved impulse control, problem-solving, reduced stress and anxiety, motivation, optimism, and happiness in general.

If you have ever felt “high” or euphoric about an accomplishment, or felt a sudden burst of motivation or excitement for something you are about to do or experience, this is the result of a dopamine rush.

The Best Supplements to Increase Dopamine

If you're interested in increasing your dopamine levels naturally, you might consider looking into a dopamine supplement. However, before you begin using a supplement, there are a few things you should know. For starters, you should know about the ingredients. Also, you should be aware of the side effects of the ingredients. If you have any concerns, consult a health care professional before using any supplements.


Vyvamind is an over-the-counter brain supplement that contains the dopamine boosting ingredients that work in a similar way as prescription ADHD medication, but without the harmful side effects or addiction risks. It works as a natural stimulant in the brain, increasing mental energy, improving focus, and improving memory. The best part is that it works quickly, with noticeable results within 45 minutes of taking it.

The natural ingredients used in this supplement are all clinically proven to help cognitive function. Choline, a crucial nutrient, plays a key role in the production of acetylcholine, a neurotransmitter that is essential to learning, memory, and concentration. It is also known to boost mood and reduce anxiety.

Vyvamind has been shown to work quickly in reducing brain fog and boosting attention. It contains a potent blend of six ingredients including L-tyrosine and caffeine to boost your energy levels and improve your focus. It also contains powerful antioxidants that help protect the brain from damage. It also boosts levels of dopamine and norepinephrine, which are essential for cognitive function and motivation.

Mind Lab Pro

Just like ginkgo biloba, Mind Lab Pro is a “universal” nootropic that is proven to improve cognitive performance and support the production and release of dopamine.

Containing a stack of ingredients (11 in total, several of which are listed above), Mind Lab Pro acts as an all-in-one supplement for optimizing brain performance, from sharpened focus, memory processing, and detoxification, to brain cell health and problem-solving.

Similar to the other supplements we have listed, Mind Lab Pro - manufactured by Opti Nutra - is a natural product, being vegan and gluten-free with no additives or preservatives. It is also FDA-approved.

Mind Lab Pro includes vitamin B6, vitamin B12, l-tyrosine, and l-theanine, and therefore offers multiple benefits for our cognition and subsequently the natural production of dopamine in our system.

Explained simply, nootropics, like Mind Lab Pro, are supplements that contain multiple premium ingredients that provide various health benefits. For many, these are seen as convenient, all-in-ones solutions for improving overall health and day-to-day performance.


As mentioned, dopamine is created through several of the amino acids found in protein. And one of these important amino acids is l-tyrosine.

In fact, l-tyrosine - while made by another amino acid, phenylalanine - is responsible for producing and supporting multiple neurotransmitters in addition to dopamine. These include norepinephrine and epinephrine.

Yet, despite being a non-essential amino acid, the importance of l-tyrosine is understated. L-tyrosine is available to use as a powder and capsule supplement, and it is highly popular among weightlifters and athletes for its ability to repair muscle tissue and quicken recovery.

But it isn’t just for weightlifters and athletes. L-tyrosine’s benefits are widely recognized for increasing dopamine production. And, of course, without a “reserve” of dopamine for our brains to release, our cognitive ability and overall quality of mood would suffer.


Did you know that dopamine production is helped by eating high-protein foods?

Amino acids, compounds found in protein, are direct producers of dopamine, and one of these crucial amino acids is l-theanine.

There are a handful of studies that show l-theanine contributes to dopamine production. Not only that, but it can improve neurotransmitters (that send signals to your brain) - one of which is dopamine.

L-theanine is available as a supplement, and is therefore used by many as a natural dopamine supplement to improve brain functionality and general happiness of mood.

Panax Ginseng

Panax ginseng is a plant with multiple health benefits, ranging from improving the immune system and cardiovascular system to promoting better cognition and a more positive outlook in general.

For this reason, there is widespread support among scientists and psychologists that Panax ginseng does in fact contribute to dopamine production and its natural process in the brain.

It has also been a trusted traditional medicine of China and Korea for centuries, where it has been used to treat inflammation, fatigue, and weak immune systems.

Panax ginseng root extract is taken orally as a powder, or in capsule form, and is 100% natural as a dopamine supplement, as well as a medicinal treatment.

Ginkgo Biloba

Ginkgo biloba is a tree that grows in China. The benefits of taking ginkgo biloba include increasing blood circulation, treating inflammation, reducing anxiety, and improving brain function and overall mental well-being.

It is for this reason that ginkgo biloba is widely used as a nootropic.

The benefits of ginkgo biloba also extend to vision support, treating depression, curing headaches, and multiple claims that ginkgo includes powerful antioxidants, which fight free radicals in our blood cells.

As described, ginkgo biloba has numerous benefits that contribute to its status as a “universal” supplement that can improve cognition and bodily functions at the same time.

It is widely available and consumed orally as a mixable powder or tablet/capsule.

Mucuna Pruriens

Mucuna pruriens is another natural supplement reported to increase dopamine production because of its high-protein content containing multiple amino acids.

The popular supplement, extracted from the tropical velvet bean plant native to Africa and Asia, provides numerous health benefits such as curing anxiety, treating infertility in males (aphrodisiac qualities), and improving general brain health.

Mostly taken as a stress reliever or anxiety fix, mucuna pruriens has the ability to improve cognition, hence its relation to supporting dopamine and its natural involvement as part of the brain’s reward system.

Vitamin B6 and Vitamin B12

Vitamin B6 and vitamin B12 are readily available supplements that contribute to the production of both dopamine and serotonin.

Serotonin, called the “happy hormone”, is related to dopamine as a neurotransmitter and chemical release in the brain as a direct response to a positive emotion or thought.

As a result, deficiencies of either vitamin B6 and vitamin B12 can lead to low self-esteem, irritability, stress, and subsequently a drop in appetite, a lack of motivation, or disrupted sleep.

Vitamin B6 and vitamin B16 can be directly consumed from a wide variety of foods, including vegetables and protein-rich beans, meat, and fish.

However, many opt to take vitamin B6 and vitamin B16 to maintain and manage their general well-being as an effective, and entirely natural, dopamine supplement and serotonin supplement.


Magnesium is one of the most popular supplements you can buy, and its healthful benefits have the science to back it up.

Magnesium is a mineral that is proven to benefit brain health and fix common ailments, specifically chronic headaches and migraines.

While magnesium is found throughout the body, an increase in magnesium through dietary means or supplementary means is reported to improve general health significantly. This includes treating PMS, lowering blood pressure, and reducing inflammation.

A natural result of magnesium’s ability to cure headaches is for the brain to function optimally. When we experience headaches and migraines, stress and toxins cloud the brain (brain fog), posing a threat to the release of dopamine and our capacity to perceive it.

Foods That Boost Dopamine Production

Dopamine cannot be eaten, as is it not found in any food source as something that can be directly consumed and absorbed by the body.

However, just like the above supplement, there are foods that we can eat to boost dopamine production and support its natural process as a neurotransmitter.

In fact, mucura pruriens, l-tyrosine, and l-theanine (listed above) are extracted from food themselves. L-tyrosine and l-theanine are found in high-protein foods, while mucura pruriens is taken from the velvet bean, a legume native to various tropical countries.

L-theanine is also found in green tea. Magnesium, as another example, can be consumed in dark chocolate.

Numerous studies have also shown that dopamine, around 50% of it, is produced in the gut. To support this, probiotics can be particularly useful for improving gut health, while making sure to keep the processes of the gut functioning optimally.

Both probiotic drinks and yogurts can therefore be consumed regularly to improve dopamine production and increase dopamine levels to a significant extent.


Dopamine is key to maintaining our motivation levels, happiness, and general mental well-being. It aids cognitive ability, which as a result can determine how focused, alert, and productive we are at work, as well as how well we perform everyday tasks.

Taking dopamine supplements, for these reasons, offers a simple solution to increasing dopamine production and supporting its natural release in the brain.

While supplements are always optional, there are natural dopamine supplements that are safe to take, allowing us to enjoy the many benefits of dopamine, and avoid the symptoms of dopamine deficiency, in a way that is convenient and organic.