Stresam: Review of Nootropic Benefits, Uses, & Effects

Updated on September 2, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

Go out of the confines of your bedroom and enjoy life with other people. You can fight social anxiety disorder with Stresam.

Many supplements are swarming the market, claiming to relieve anxiety disorders. Instead of trying all of them, you have to do in-depth research by reading information about the product or reading reviews, just like this Stresam review.

If you want to know more about Stresam, read on.

What is Stresam (Etifoxine)?

Stresam is a non-benzodiazepine anxiolytic (anti-anxiety) and anticonvulsant drug created for the treatment course of anxiety disorders in France, Malta, Bulgaria, and Romania. Etifoxine is the active ingredient in the medication.

stresam information

It is a benzoxazine derivative with a unique mode of action that sets it apart from other anxiolytics. In terms of the influence on the development of the anxiety symptom complex, it is characterized by maximum selectivity and physiological action.

The supplement is also used to treat anxiety disorders like generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder and help people with peripheral neuropathy recover their nerves.

Biocodex, a French pharmaceutical firm, produces Stresam. When benzodiazepines (psychoactive chemicals with sedative effects) dominated the market for sedatives and medications for anxiety disorders in the 1960s, the active substance was produced by a German pharmaceutical company.

Despite their widespread use, benzodiazepine tranquilizers have several adverse side effects, including psychomotor inhibition, sleepiness, lethargy, dizziness, muscle relaxation, cognitive impairment, addiction, and so on.

According to studies, the activation, synthesis, and deployment of next-generation non-benzodiazepine anxiolytics was an alternate method for developing anti-anxiety medications. Etifoxine was one of many anxiolytics that could replace benzodiazepine medications.

How Does Stresam Drug Work in the Body?

Although the mechanisms of etifoxine's action are unknown, it is known to bind to the same target binding sites (neurotransmitter 1 receptors) on nerve cells as GABA (gamma-aminobutyric acid). GABA is a neurotransmitter (a substance that communicates between nerve cells) that inhibits specific brain processes.

Etifoxine both directly and indirectly replicates the impact of GABA, resulting in a calming effect in the amygdala that aids in the regulation of anxiety symptoms.

It is a specific antagonist of the GABAA receptor, a protein found in the membrane of cells. The receptor is part of a complex that helps the potentiation of nerve signals and is essential for regulating brain function.

The GABAA receptor is part of a protein complex structure called the GABAA receptor complex. It is an integral part of the inhibitory neurotransmitter system in the brain, and the GABAergic receptor complex is responsible for inhibiting nerve signals in the brain.

The etifoxine-GABA complex binds to the receptor, which results in the inhibition of nerve signals and the calming of anxiety. Its efficacy for healing anxiety and as an antidepressant made it a reputable medicine by some doctors.

It's used to treat anxiety disorders like generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder and help people with peripheral neuropathy recover their nerves. Overall, patients treated with Stressm have improved, as shown in the pain anxiety symptoms scale.

Benefits and Actions of Stresam Treatment

Patients with muscle pain, headaches, or functional gastrointestinal issues are 2.5-10 times more likely to have a positive match for a pain condition, generalized anxiety disorder, or major depressive illness in a primary care context.

stresam benefits

While there are other types of medications available, Stressam as an anti-depressant offers the following benefits:

  • Relief from anxiety and stress
  • Reduced symptoms of pain
  • Increased levels of energy and improved sleep
  • Increased ability to concentrate
  • Reduced levels of fatigue
  • Enhanced ability to cope with stress
  • Stress is a significant factor in the onset and exacerbation of many conditions, and it is the number one cause of depression and anxiety.
  • Etifoxine provides the following benefits:
  • Reduces the severity of symptoms
  • Improves the ability to cope with stress
  • Reduces anxiety

Etifoxine is effective in reducing the symptoms of anxiety and stress, but it also improves the overall quality of life.

It is an essential part of a comprehensive treatment plan that includes other therapies, lifestyle, and behavioral modifications.

Stresam Experiences and Reviews Shared on (Etifoxine) Reddit

Stress-related disorders are prevalent, affecting an estimated 30% of the general population at some point in their lives. But still, many people have shared their experiences in using tranquilizers such as Stresam. Here are some of them.

According to Yoyomamahh:

"I had mixed results. Like it was mentally stimulating but physically relaxing, which was an interesting, unique little effect I got from it. I wouldn't say it was specifically beneficial or that I would try it again, but at the same time, it wasn't an unpleasant experience."

According to NostalgicArcticEmo:

"Etifoxine is a decent anxiolytic if your GABA receptor isn't already down-regulated, time. At 50-100 mg, it produces anxiolytic effects similar to benzo like diclazepam, but without the typical side effects of diazepines, such as memory and muscle control loss, as well as psychological dependence. I haven't used it that often but when I do, there's still some very slight sedation that accompanies the anxiety relief, but it seems to go away once it reaches its peak effects."

According to anonymous:

"Tried etifoxine, wasn't super impressed. I think if these novel Russian drugs were as good as they're touted, then they'd be a lot more popular. I'd personally look into gabapentin if I were you instead if you're looking for a non-benzo GABA drug."

Where to Buy Stresam?

If you are one of those worrying about alleviating your anxiety and tension, you can try using Stresam.

Stresam is often available with a doctor's prescription. However, in some countries, you can buy it over-the-counter. You can also try buying from reputable websites such as Cosmic Nootropic. Aside from Stresam, it also has a line of other nootropic supplements that you can buy in retail or bulk.

Stream's tablet capsule form is priced at $51.50 in 60 capsule bottles plus the shipping fee.

Stresam Dosage for Stimulation and Reduce Anxiety Levels

In general, the etifoxine anxiolytic Stresam can be said to help treat a wide range of anxiety-neurotic diseases and psychosomatic pathologies, including sleep problems, vegetative-vascular dystonia, and so on.

The usual dose is 1-2 capsules 2-3 times a day from one week to two months. Alternatively, you might take 150 mg every day for no more than 12 weeks.

Overdosage is only noticeable at doses several times larger than those recommended, and it is restricted to the consequences of hypotension, which are easily treated.

Contraindications with other Medicines

There are no contraindications to Stresam. It is not recommended for pregnant, breastfeeding, or planning on becoming pregnant.

Stresam Performance Side Effects & Safety

Like all medications, Stresam can have side effects. The most common side effects are drowsiness, fatigue, and dizziness.

stresam side effects

The side effects are usually mild and transient. When taken in the proper dosage, Stresam has no severe side effects.

Side effects of the peripheral benzodiazepine receptor can include:

  • headache
  • mild nausea
  • muscle cramps
  • nervousness
  • stomach upset

To avoid side effects, you should take Stresam as recommended.

You should also note that Stresam can interact with some other medications in some events, and it can interact with some herbs and supplements.

For instance, Stresam can interact with the following:

  • anxiety-depression drugs like tricyclics and selective serotonin reuptake inhibitors
  • antihistamines
  • caffeine
  • alcohol
  • herbs and supplements that contain caffeine

If you experience any side effects while taking Stresam, you should stop taking it immediately and contact your doctor.

Frequently Asked Questions (FAQ)

Your questions answered.

When to Stop Stresam?

It would help if you did not stop taking Stresam unless your doctor says so. Stopping it abruptly can cause withdrawal symptoms.

If you take Stresam for longer than two months, you should gradually lower your dosage.

Does Stresam Make You Sleepy?

Drowsiness appears in the initial few days of treatment and goes away on its own as the therapy continues.

Is Stresam Addictive?

Although Stresam is not classified as addictive (definitely not as addictive as benzodiazepines) and stopping therapy with Strezam is not thought to produce withdrawal syndrome, treatment with the medicine should only be terminated as recommended by your doctor.

Is Stresam Good for Anxiety?

Stresam is a good anxiety therapy to try because it has few side effects and does not carry the hazards of the over-the-counter benzo medicines (Valium and others), which can be addictive and impair attention, among other things. Many people find it to be a good fit for them.

Stresam Review: Conclusion

Anxiety is widespread in many painful syndromes, such as myofascial pain syndrome, fibromyalgia, and sympathetic maintained pain syndromes. Compared to benzodiazepines, etifoxine causes less anterograde amnesia, drowsiness, reduced psychomotor function, and withdrawal episodes.

But, the drug also has a high incidence of side effects, and it can interact with other medications and supplements.

Despite its disadvantages, Stresam is still worth trying. It has a good safety profile, and it can be considered a valuable supplement for anxiety and tension.