8 Best Nootropics for Hangover in 2024 (Tested & Reviewed)

Updated on March 2, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
Exploring the role of nootropics in alleviating hangover symptoms and promoting brain health.

Hangovers are never fun. 

But if you’ve had one too many the night before, then you don’t have to suffer through the next day.

We’ve rounded up the best nootropics that can help you recover quickly and get back to your regular schedule. 

Read on to find out which ones work best for hangover recovery!

Top 8 Nootropics for Recovering From a Hangover

  • Vyvamind — Best to boost cognition and brain health
  • Modafinil — Best to promote wakefulness
  • Taurine — Great protection against oxidative stress
  • Rhodiola Rosea — Best natural nootropic against anxiety
  • Alpha GPC — Great against alcohol-induced neurotoxicity
  • B Vitamins — Great to support metabolic processes in the body
  • Citicoline — Best for improving memory and learning
  • Oxiracetam — Great for enhancing attention and logical thinking

How to Choose the Best Nootropics for Hangover?

Choosing the right nootropics for hangover relief is about understanding the specific factors that can influence their effectiveness and safety.

FactorDescriptionWhy It’s Important
Ingredient QualityThe purity and sourcing of nootropic components.High-quality ingredients ensure safety and efficacy.
Dosage & SynergyThe amount of each ingredient and how they interact with each other.Correct dosages and complementary effects can maximize benefits.
Specificity to SymptomsHow well the nootropic targets hangover symptoms like headache or cognitive fog.Targeted relief means faster recovery.
Scientific BackingEvidence from research and clinical trials supporting the use of nootropics for hangover relief.Ensures that the product’s claims are credible.
Side Effects & InteractionsThe potential adverse reactions or interactions with alcohol or other medications.Minimizes risk and ensures safe consumption.
  • Ingredient Quality: High-quality ingredients are crucial for ensuring that the nootropic is both safe and effective. Avoiding low-grade or impure components reduces the risk of adverse effects and enhances the likelihood of hangover relief.
  • Dosage & Synergy: It’s important to consider not just the individual dosage of components, but also how they work together. The right balance and synergy between ingredients can enhance their overall effectiveness.
  • Specificity to Symptoms: A nootropic that’s formulated to address specific hangover symptoms is likely to be more effective. Look for products that target your most troublesome symptoms, such as nausea, headache, or mental fog.
  • Scientific Backing: Nootropics backed by scientific research and clinical trials offer a level of credibility and reassurance that they are effective for hangover relief.
  • Side Effects & Interactions: Understanding any potential side effects or interactions with other substances, especially alcohol, is essential to ensure that the nootropic won’t exacerbate your hangover or create new health issues.

The Best Nootropics for a Hangover of 2024

According to our in-depth research and testing, the top nootropics for a hangover are:

1. Vyvamind

Vyvamind is a fast-acting nootropic supplement that can help with hangover symptoms. It contains natural ingredients like Vitamin B6, Vitamin B12, L-Tyrosine, CDP Choline, L-Theanine, and Caffeine Anhydrous that work together to provide a boost of mental energy and clarity. The B vitamins in Vyvamind can help convert food into energy and reduce brain fog and fatigue. L-Tyrosine increases dopamine levels to improve focus and motivation.

CDP Choline increases acetylcholine production for improved learning ability and memory. L-Theanine promotes relaxation without drowsiness, and Caffeine Anhydrous provides a boost of mental energy. When these two are combined or stacked, they result in increased alertness and improved task performance. Vyvamind is a safe and effective way to get rid of hangover symptoms quickly and improve cognitive performance.

2. Modafinil

Modafinil is a powerful nootropic that is known to promote wakefulness(1), alertness, and improved cognition. It is often used to treat narcolepsy, but is also a great tool for those suffering from a hangover. Its wakefulness-promoting effects help to reduce fatigue and improve overall cognitive performance.

Modafinil also has the added benefit of reducing nausea and headaches that can be associated with a hangover. It is important to note, however, that Modafinil should not be used as a substitute for proper sleep hygiene and should only be taken as needed. Taking Modafinil too often can lead to insomnia and other sleep disturbances so it should be used with caution.

3. Taurine

Taurine is another nootropic that can help combat the effects of a hangover. It is an amino acid that plays an essential role in many bodily functions and has been found to have antioxidant and anti-inflammatory properties(2) which can help reduce the symptoms of a hangover. It is also thought to help protect cells from damage caused by alcohol consumption.

Studies have also shown that taking taurine before drinking can help reduce the severity of the hangover the next morning. It’s important to remember though, that taurine should be taken before drinking, not after, as it won’t have any effect on the hangover symptoms at this point. Taurine is readily available in many forms, making it easy to take and very convenient.

4. Rhodiola Rosea

Rhodiola Rosea is a powerful adaptogen that can help reduce stress and fatigue, making it an ideal nootropic for hangovers. It has been used for centuries for its medicinal properties, and recent studies have demonstrated its effectiveness in reducing the severity of hangovers.

Rhodiola Rosea helps the body cope with stress from alcohol consumption, which in turn reduces the symptoms of a hangover. It helps to regulate cortisol levels and boosts energy levels, so you can get back on your feet in no time. Rhodiola Rosea can also increase serotonin levels, helping to raise your mood and reduce anxiety.

Its anti-inflammatory properties also make it an ideal supplement for reducing the severity of hangovers. When taken in combination with other nootropics, Rhodiola Rosea can help reduce the symptoms of a hangover quickly and effectively.

5. Alpha GPC

Alpha GPC is a powerful nootropic compound that is derived from soy and is known to be one of the best natural nootropics for hangover. It helps to protect against alcohol-induced neurotoxicity and can be used to reduce the severity of hangover symptoms. Alpha GPC is also known to reduce stress, improve focus, and improve memory.

It can also help to increase energy levels and cognitive performance, making it an ideal choice for those looking to recover from a hangover. Alpha GPC also helps to protect the brain cells from alcohol-induced damage and can even help to reduce withdrawal symptoms. For those looking for a natural way to get rid of their hangover, Alpha GPC is a great option.

6. B Vitamins

B vitamins are thought to be beneficial in helping to reduce the symptoms of a hangover. Studies suggest that alcohol depletes vitamin B-1 from the body, and so supplementing with B vitamins before and after drinking can help replenish lost nutrients. Studies have also shown that taking B12 supplements before and after drinking alcohol may help reduce hangover symptoms, as can a supplement containing vitamins B-1, B-2 and B-6.

Vitamin B complex have also been found to reduce alcohol-induced brain damage and boost energy levels. However, the only reliable hangover cure is limiting alcohol intake in the first place. Taking a pill that includes B vitamins is recommended as a way to ensure that your body is getting all the necessary vitamins.

7. Citicoline

Citicoline is a natural nootropic that has been used to treat a variety of neurological conditions, such as Alzheimer’s disease, dementia, and strokes. It also helps with liver detoxification, allowing the body to process alcohol more efficiently. Citicoline supplements can be taken before and after drinking alcohol, providing a safe and natural way to protect against hangovers.

Besides its ability to reduce the intensity of a hangover, citicoline is also known for its other health benefits, such as improving cognitive function, reducing fatigue levels, and even lowering blood pressure. Citicoline works by increasing levels of acetylcholine, a neurotransmitter in the brain that helps with memory and learning.

8. Oxiracetam

Oxiracetam is another popular nootropic that is gaining traction in the hangover recovery world. It’s a synthetic supplement that is related to piracetam, but with a greater effect on improving cognitive function. This can be especially beneficial after a night of drinking because it helps to sharpen your focus and restore some of the mental clarity you lose after drinking.

Additionally, oxiracetam can help protect the brain from long-term damage due to alcohol consumption. It’s important to note, however, that oxiracetam is not regulated by the FDA and should be used with caution.

What to Consider Before Buying Nootropics for Hangover Relief?

There are several considerations to evaluate before purchasing nootropics for hangover relief to ensure that you’re selecting the most appropriate product for your needs.

1. Personal Sensitivities and Allergies

Recognizing any personal sensitivities or allergies to ingredients in nootropics is crucial. This precaution helps to prevent negative reactions that could compound hangover symptoms.

2. Lifestyle and Drinking Habits

Your alcohol consumption patterns should influence your choice of nootropic. For infrequent drinkers, a single-use nootropic may suffice, while regular consumers may benefit from a product designed for more consistent use.

3. Cost vs. Budget

Financial considerations are important when selecting nootropics. There are effective products available at different price points, so it’s worth finding one that provides value without straining your budget.

4. Availability and Accessibility

The availability of the nootropic, whether it’s in physical stores or online, can affect your choice. Opt for a nootropic that is easily accessible whenever you need it.

5. Long-Term Effects and Sustainability

Consider the long-term implications of using nootropics for hangover relief. Choose a product that not only offers immediate benefits but also supports overall cognitive health without fostering dependence or other adverse effects.

How We Picked the Top Nootropics for Hangover Relief

We implemented a comprehensive review process to pinpoint the best nootropics for alleviating hangover symptoms. Our evaluation incorporated factors such as effectiveness, ingredients, scientific evidence, brand reputation, product transparency, manufacturing process, user feedback, price, and overall value. Each aspect was thoroughly analyzed to provide a reliable and well-rounded list of nootropics for hangover relief.


We assessed clinical evidence and user testimonials focusing on the alleviation of hangover symptoms, such as cognitive fog, headache, and fatigue.


Our analysis prioritized natural, potent, and research-supported ingredients that target hangover symptoms and promote overall cognitive function.

Scientific Evidence

We verified the efficacy of key ingredients based on peer-reviewed studies and meta-analyses, emphasizing their role in relieving hangover symptoms.


We evaluated appropriate dosage levels and ingredient proportions, ensuring they correspond with existing research for optimal results.


We ascertained the safety of each component, accounting for potential side effects and interactions while abiding by regulatory guidelines. Prioritization was given to FDA-approved ingredients.

Brand Reputation

We examined brands’ credibility and reliability through customer reviews, expert recommendations, and company background.

Product Transparency

We valued full disclosure of ingredients, including their sources, amounts, and concentrations, thus empowering consumers to make informed decisions.

Manufacturing Process

We analyzed manufacturing standards, prioritizing products made in certified facilities and adhering to Good Manufacturing Practices (GMP).

User Reviews

We considered real customer feedback, placing emphasis on testimonials describing improvements in hangover symptoms and cognitive recovery.


We compared product prices, ensuring competitiveness and alignment with the quality and efficacy of the nootropic.


We evaluated overall value based on a balance of price, quality, and efficacy to guarantee optimal investment returns for consumers.

How Can Nootropics Help with Hangover?

Nootropics have been gaining popularity in recent years as an alternative to traditional hangover remedies. Studies have shown that certain nootropics can reduce the symptoms of a hangover. For example, Vyvamind has been found to be effective in preventing the symptoms of a hangover, while Alpha GPC can improve cognitive function, Modafinil has been found to reduce feelings of fatigue and nausea, and Rhodiola rosea can reduce stress levels.

Taking a combination of nootropics such as Taurine and B vitamins before drinking alcohol can also help reduce the risk of developing a hangover.

The Benefits of Nootropics in Curing a Hangover

Nootropics are known for their ability to improve cognitive function, but they can also be used to ease the symptoms of a hangover. Many nootropics have anti-inflammatory and anti-oxidant effects, which can help to reduce the severity of a hangover. Nootropics can also help to boost energy levels and improve focus, which can be helpful when dealing with a hangover.

Vyvamind, Modafinil, Taurine, Rhodiola Rosea, Alpha GPC, B vitamins, Citicoline and Oxiracetam are some of the most popular nootropics for hangover relief. These nootropics contain compounds that can reduce inflammation, improve energy levels and help to restore balance to the body’s natural functions.

The Safety and Side Effects of Taking Nootropics for Hangovers

When it comes to taking nootropics to help with a hangover, safety should be a priority. It’s important to be aware of the potential side effects of taking nootropics, as well as any potential interactions with other medications or supplements. Some of the more common side effects include headaches, dizziness, drowsiness, and nausea.

It’s also important to read labels carefully and pay attention to any warnings or cautions associated with particular nootropics. For example, some nootropics may contain ingredients that can interact negatively with certain medications. Additionally, some nootropics may interact with alcohol and should not be taken while drinking.

It’s also important to remember that it is possible to overdo it when it comes to taking nootropics for hangovers. Taking too much can lead to an intense headache or dizziness, so it’s important to start off slow and increase the dosage gradually as needed.

Finally, it’s always a good idea to talk to your doctor before taking any supplement or medication for a hangover or any other health issue. Your doctor can help you determine if the nootropic you are considering is safe for you and can provide advice on proper dosing and possible interactions.

Tips on Choosing the Right Nootropic for Hangovers

When it comes to choosing the right nootropic for your hangover, there are a few things to consider.

  • First, you want to find a supplement that contains a combination of natural ingredients that have been proven to help with hangover symptoms.
  • Second, you want to make sure that the supplement is safe and free from any side effects.
  • Third, you want to make sure it is strong enough to effectively help with your hangover symptoms.

To ensure you’re getting the most out of your nootropic supplement, it’s important to read the labels and research the ingredients carefully. It’s also important to take note of the dosage instructions on the product label. Make sure you follow them carefully as taking too much or too little can be ineffective and potentially dangerous.

Also, keep in mind that different nootropics may work better for different people, so it’s important to do some trial and error before settling on a particular supplement. By taking the time to do some research and choose the right nootropic for your needs, you can rest assured that you’ll find one that is both safe and effective in helping you tackle your hangover symptoms

Nootropics for Hangover in Summary

Taking nootropics for hangover is a great way to prevent the dreaded morning-after symptoms. The natural ingredients contained in nootropics have been shown to be effective in reducing the effects of a hangover, while also providing a boost in mental clarity and focus.

However, it is important to take into consideration the safety and side effects of each nootropic before making any decisions. Many nootropics are not regulated by the FDA, so it is important to do your research and consult with a medical professional if you are unsure about taking them.

Another important factor to consider is that nootropics can be taken in combination with other drugs or supplements, so it is best to check with your doctor or pharmacist before combining them with any other medications.

Overall, taking nootropics for hangover can provide you with the relief you need and help you get back to your regular routine sooner. With careful consideration and research, you can find the right nootropic for your individual needs.

Sources, Studies, and Scientific Research
  1. Cao Y, Li Q, Liu L, Wu H, Huang F, Wang C, Lan Y, Zheng F, Xing F, Zhou Q, Li Q, Shi H, Zhang B, Wang Z, Wu X. Modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation. Br J Pharmacol. 2019 May;176(9):1282-1297. doi: 10.1111/bph.14626. Epub 2019 Apr 2. PMID: 30767208; PMCID: PMC6468261. ↩
  2. Marcinkiewicz J, Kontny E. Taurine and inflammatory diseases. Amino Acids. 2014 Jan;46(1):7-20. doi: 10.1007/s00726-012-1361-4. Epub 2012 Jul 19. PMID: 22810731; PMCID: PMC3894431. ↩