8 Best Nootropics for Relaxation from Stress in 2023

Updated on August 19, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

Are you looking to relax and destress?

Do you need a little bit of help unwinding after a long day?

If so, then nootropics could be the answer.

In this guide, we'll discuss some of the best nootropics to help you relax and de-stress.

Best Nootropics for Relaxation

  • Nooceptin — Best nootropic stack to promote relaxation
  • L-Theanine — Best amino acid that has a calming effect
  • Kava Kava — Great herbal supplement to reduce anxiety
  • Ashwagandha — Best root extract to remove stress and fatigue
  • Valerian Root — Best to increase GABA levels
  • Passionflower — Great for improving sleep quality and mood
  • L-Tryptophan — Great for increasing serotonin levels in brain
  • Lemon Balm — Great for boosting mood and memory

1. Nooceptin

Nooceptin contains several powerful nootropic ingredients that work together to help promote relaxation. These include Rhodiola Rosea, Bacopa Monnieri, and L-Theanine. Rhodiola Rosea is an adaptogen that helps the body adapt to stressors, while Bacopa Monnieri helps protect the brain from the harmful effects of stress.

Finally, L-Theanine is an amino acid found naturally in green tea that helps reduce stress and improve cognitive performance. Together, these ingredients work to reduce stress, improve focus, and help you relax and stay calm throughout the day.

2. L-Theanine

L-Theanine is an amino acid that can be found naturally in green tea leaves, and it is known to have a calming and relaxing effect. It is believed to reduce stress and anxiety, improve mental clarity and focus, and help with sleep(1).

Studies have also shown that L-Theanine can help reduce blood pressure and improve heart health. It is also known to interact with the neurotransmitter GABA, which can help relax the body and mind. For those looking to find a natural way to relax, L-Theanine may be an effective nootropic to consider.

3. Kava Kava

Kava Kava is a natural herbal supplement that is used for its calming and relaxing effects. It is derived from the root of a plant native to the South Pacific and contains kavalactones, which are responsible for its calming effect. Kava can be taken in tea, capsule, powder or liquid form and is known to help reduce anxiety, improve sleep quality, and relax the body and mind.

Studies suggest that kava may help to reduce stress and tension, improve cognitive function, and even reduce the risk of depression(2). With its calming effects, Kava Kava is a popular choice for those looking for a natural way to relax and de-stress.

4. Ashwagandha

Ashwagandha is an Ayurvedic herb that has been used for centuries to help people relax and reduce stress. It has been found to be effective in reducing anxiety(3), promoting better sleep, and boosting cognitive functions, including memory and focus.

Additionally, ashwagandha has been shown to reduce cortisol levels, which is linked to stress and anxiety. It has also been used to help with depression and fatigue. Ashwagandha is available in supplement form and can be taken daily for best results.

5. Valerian Root

Valerian root is a popular herb used in traditional medicine to promote relaxation. It has been used for centuries to treat insomnia, anxiety, and restlessness. Valerian root has been found to contain a number of active compounds which work together to reduce stress and anxiety. It is also believed to reduce inflammation, improve sleep, and even act as an anti-depressant.

In addition to its calming effects, valerian root can also improve cognitive functions like focus and memory. It is thought to do this by increasing levels of gamma-aminobutyric acid (GABA) in the brain. GABA is an important neurotransmitter that helps regulate mood, emotion, and sleep. By increasing GABA levels, valerian root can help reduce feelings of stress and anxiety, while also improving focus and memory.

6. Passionflower

Passionflower is a flowering plant that has been used for its calming and relaxing effects since the 16th century. It is known to have sedative and anti-anxiety effects, making it a great choice for those looking for a natural remedy for their stress and anxiety. Passionflower helps to reduce stress by increasing levels of gamma-aminobutyric acid (GABA) in the brain, which acts as a neurotransmitter to help regulate mood and reduce anxiety(4).

Also, passionflower can help improve sleep quality and reduce insomnia. While there is still more research needed to understand the full effects of passionflower on relaxation, it is a great natural remedy for those looking for an alternative to traditional medication.

7. L-Tryptophan

L-Tryptophan is an essential amino acid and a natural precursor to serotonin, the neurotransmitter responsible for regulating mood and promoting relaxation. Research has shown that L-tryptophan can have a calming effect on mood, helping to reduce feelings of stress and anxiety. It has also been found to be effective in treating insomnia and improving sleep quality.

Taking L-tryptophan may help to reduce the physical sensations of stress, such as increased heart rate, sweating, and muscle tension. Additionally, it may also be beneficial for improving cognitive functioning, and may even reduce symptoms of depression.

8. Lemon Balm

Lemon balm is a member of the mint family and has been used to reduce stress and anxiety for centuries. It has a calming effect on the nervous system and can help improve sleep. It also helps to boost cognitive functions like memory and focus. Lemon balm works by increasing levels of GABA, which is an inhibitory neurotransmitter that helps to reduce anxiety. It also contains flavonoids which have antioxidant and anti-inflammatory properties.

Taking lemon balm in supplement form can help to reduce stress and anxiety levels(5), improve sleep, and boost cognitive functions.

How We Picked the Top Nootropics for Relaxation

We employed a comprehensive review process to identify the best nootropics for relaxation. Our evaluation included factors such as effectiveness, ingredient quality, brand reputation, transparency, manufacturing standards, user feedback, price, and overall value. We analyzed each of these aspects to present a reliable and well-rounded list of the top relaxation-promoting nootropics.


We examined clinical studies and user experiences to measure the potential for stress reduction, mental relaxation, and overall mood improvement.


We carefully inspected each formula, emphasizing evidence-supported, natural, and high-quality components that enhance relaxation and stress relief.

Scientific Evidence

We consulted peer-reviewed research and meta-analyses to verify the effectiveness of key ingredients in promoting relaxation.


We assessed appropriate dosages and ingredient ratios, ensuring they correspond with established research for optimum results.


We confirmed the safety of each ingredient by considering potential side effects and interactions, while also adhering to regulatory guidelines. We prioritized FDA-approved ingredients.

Brand Reputation

We evaluated the credibility and trustworthiness of each brand through customer reviews, expert endorsements, and company history.

Product Transparency

We valued full disclosure of ingredients, including their sources and concentrations, to enable informed consumer decision-making.

Manufacturing Process

We verified manufacturing standards, prioritizing products made in certified facilities and in compliance with Good Manufacturing Practices (GMP).

User Reviews

We analyzed real customer feedback, giving weight to testimonials that highlight relaxation benefits and stress reduction.


We compared product prices, ensuring they were competitive and reflected the quality and efficacy of the nootropic.


We evaluated overall value by considering the balance of price, quality, and effectiveness to ensure the best return on investment for users.

How Can Nootropics Help with Relexation?

Nootropics are substances that are designed to improve cognitive functions such as memory, learning, focus and alertness. For those looking to relax, nootropics can be beneficial in a number of ways. Nootropics can help to reduce stress and anxiety, improve sleep, and provide a feeling of calmness and clarity.

best nootropics for relaxation

They can also help to reduce fatigue and improve mental clarity and focus. By taking nootropics regularly, one can experience improved relaxation and mental clarity, allowing them to better handle stressful situations.

The Benefits of Nootropics for Relexation

Nootropics offer a wide range of potential benefits for relaxation. They can help to improve focus, reduce stress and anxiety levels, and enhance cognitive functions such as memory and concentration. Nootropics can also boost mood and improve sleep quality, which can be beneficial for relaxation.

These supplements are safe to use and are generally well-tolerated, with few side effects. However, it is important to choose the right nootropics for your needs and to consult a doctor or healthcare professional if you have any concerns or questions.

The Safety and Side Effects of Taking Nootropics for Relexation

When it comes to taking nootropics to help with relaxation, it’s important to remember that they are still drugs, and they can have side effects and safety concerns. Even natural nootropics, such as herbs and vitamins, can have side effects and interactions with other medications. Before taking any nootropic supplement, it’s important to speak with your doctor, who can help you assess the risk and make sure that you are taking the right supplement for your needs.

It’s also important to be aware of the possible side effects of nootropics. Some of the most common side effects can include nausea, headaches, dizziness, insomnia, and irritability. Other nootropics can also cause more serious side effects, such as liver damage, increased blood pressure, and heart palpitations. If you experience any of these side effects, you should stop taking the supplement and speak with your doctor.

Tips on Choosing the Right Nootropic for Relexation

When it comes to choosing the right nootropic for relaxation, it is important to consider your individual needs and goals. Some people may find that an herbal remedy such as Kava Kava or Valerian Root can provide the relaxation they need. Others may find that an amino acid like L-Theanine or L-Tryptophan is more helpful. Additionally, some people may find that a combination of nootropics is more beneficial.

It is also important to consider the side effects of any nootropic you choose. Many nootropics can cause drowsiness and other side effects, so it is important to talk to your doctor or pharmacist about any potential side effects before taking any supplement. Additionally, it is important to make sure that the supplement you choose is of high quality and contains all the ingredients that are listed on the label.

Finally, it is important to consider the cost of the nootropic you choose. While some supplements may be more expensive than others, it is important to consider the quality of the product and ensure that it is worth the price. Taking the time to research and compare different brands can help you find a nootropic that is both effective and affordable.

Conclusion: The Pros and Cons of Taking Nootropics to Relax

Nootropics have the potential to be beneficial in helping us relax, reduce stress, and improve our cognitive functions. However, it is important to be aware of the potential risks and side effects associated with certain nootropics and to always consult with a healthcare professional before taking any nootropics.

While there are pros and cons to taking nootropics, it is important to consider the individual circumstances before deciding if nootropics are the best option for your needs. Ultimately, the decision to take nootropics should be based on the individual's needs, preferences, and goals.