5 Best Nootropics at GNC in 2024 (and Better Alternatives)

Updated on March 2, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
An article discussing the top nootropic supplements available at GNC for cognitive enhancement.

What are the best nootropics at GNC?

Are you constantly on the hunt for that magical brain booster that will supercharge your focus, memory, and cognitive abilities?

Look no further! While some may turn to coffee for a quick pick-me-up, others are delving into the fascinating world of nootropics. As a booming industry, nootropics promise to enhance various aspects of our mental prowess and are widely available at stores like GNC. But, with so many options, picking the perfect one can be a daunting task.

To save you from the hassle, we’ve scoured the aisles and compiled a list of the best nootropics at GNC, along with some even better alternatives that you’re bound to love. So, buckle up and join me on this enlightening journey to unlock your brain’s true potential!

Best Nootropics at GNC

  • Vyvamind — Best overall mental health supplement
  • NooCube — Best for improving memory and focus
  • Feedamind — Great against mental fatigue and cognitive decline
  • Mind Lab Pro — Great as a pre-workout and to provide cognitive enhancement
  • Caffeine — Best for mental alertness and sharpness

How to Choose the Best Nootropics GNC?

Selecting the right nootropics at GNC requires an understanding of key factors that contribute to their efficacy and safety. Here’s what to look for:

FactorDescriptionWhy It’s Important
Ingredient QualityThe purity and sourcing of the nootropic’s components.High-quality ingredients ensure safety and efficacy.
Clinical EvidenceThe presence of scientific research supporting the use of the nootropic.Verifies that the nootropic has been tested and proven effective.
Formulation BalanceThe right mix of ingredients and dosages in the product.Ensures that the nootropics work synergistically without adverse interactions.
Brand ReputationReputation of the manufacturer based on user reviews and industry standing.A reputable brand is more likely to produce a reliable and safe product.
Value for MoneyThe cost of the supplement relative to its benefits.Ensures that you are getting an effective product at a reasonable price.
  • Ingredient Quality: High-quality ingredients are less likely to be contaminated and more likely to deliver the intended cognitive benefits. They are typically well-sourced and backed by purity certifications.
  • Clinical Evidence: Supplements supported by clinical evidence offer assurance that they will perform as advertised. This evidence is often found in peer-reviewed journals and clinical trials.
  • Formulation Balance: A balanced formula means that the ingredients complement each other, maximizing benefits and minimizing potential side effects. Accurate dosing is crucial for efficacy and safety.
  • Brand Reputation: A good reputation indicates that the brand consistently meets quality standards and customer satisfaction. Trustworthy brands maintain transparency and have a history of positive user experiences.
  • Value for Money: The best nootropic isn’t necessarily the most expensive one. Value for money takes into account both the product’s price and its effectiveness, ensuring a good return on your investment.

The Best Nootropics at GNC for 2024

According to our in-depth research and testing, the best nootropics at GNC are:

1. Vyvamind

Vyvamind is a popular nootropic supplement available at GNC, designed to enhance cognitive function and improve overall brain health. This comprehensive formula contains a blend of vitamins, minerals, and natural ingredients known to promote mental clarity, focus, and memory. It has been shown to improve blood flow to the brain, boost cognition and reduce stress.

Many users of Vyvamind have reported experiencing improved concentration, mental stamina, and alertness after regular use of the product.(1) Additionally, the supplement supports emotional well-being and reduce symptoms of anxiety and depression.

While Vyvamind may be a good choice for those looking to give their brain a boost, it is essential to consider that the effectiveness of any nootropic can vary from individual to individual based on factors such as age, genetics, and overall health. It’s crucial to consult with a healthcare professional before starting any new supplement to ensure it’s the right fit for one’s needs.


  • Improves cognitive functioning
  • Has a positive effect on both brain and body
  • Improves focus and attention


  • May not be suitable for user with certain medical conditions

Despite its benefits, some users may find Vyvamind to be on the higher end in terms of price. For those seeking more affordable alternatives, other nootropic supplements in the market also offer comparable benefits at a lower cost.

2. NooCube

NooCube is a top-rated nootropic supplement designed to enhance cognitive functions, memory, focus, and overall brain health. Manufactured by the reputable Wolfson Brands UK Limited, NooCube is particularly popular among students and professionals looking to improve their learning and cognitive abilities. This nootropic is formulated with a blend of scientifically proven ingredients that help combat brain fog and boost the power of recall and memory. NooCube contains highly effective nootropic ingredients like Alpha-GPC, Huperzine A, Oat Straw extract, L-Tyrosine, and more.

NooCube works by decreasing stress levels, lowering cortisol levels, and reducing anxiety.(2) It also supports neurotransmitters and brain cell protection, ultimately improving memory and recall skills.(3) Studies have shown that NooCube’s ingredients optimize brain chemistry, promoting mental focus and healthy levels of neurotransmitters such as acetylcholine, serotonin, and GABA.

NooCube also supports a healthy eye-brain connection and helps the body combat oxidative stress caused by prolonged blue light exposure. Users of NooCube frequently report improved focus and attention span, even during high-pressure situations like exams or workplace presentations.


  • Significantly improves cognition and memory
  • Boosts mental clarity, focus, and energy
  • Helps keep your brain healthy


  • May not work for everyone
  • Not recommended for pregnant women

NooCube is an all-in-one stack, perfect for daily use, with all-natural ingredients and no known side effects. The product comes with a 60-day money-back guarantee and is often available with special deals and discounts on the official website.

3. Feedamind

Feedamind is an incredible nootropic supplement that has gained popularity amongst those seeking to enhance their cognitive abilities. This product boasts an efficient blend of natural ingredients that work together to improve brain function and overall mental performance. Users of Feedamind report experiencing increased focus, better memory retention, and enhanced mental clarity, making it a popular choice for individuals looking to excel in various areas of their life, be it school, work, or even personal development.

One of the main ingredients in Feedamind is Bacopa Monnieri, a well-known herb that increases the reception of nerve signals, thus improving reaction times and overall cognition.(4) This powerful herb also assists in boosting both long-term and working memory functions. Additionally, Feedamind contains Alpha GPC, which enhances the body’s production of the neurotransmitter acetylcholine, playing a crucial role in memory and learning.(5)


  • Improves mood and cognition
  • Has potent nootropic effects
  • Enhances focus, alertness, and memory


  • Not suitable for people under 18 years of age
  • May cause mild side effects for some users

Furthermore, Feedamind includes L-Theanine and L-Tyrosine, both of which contribute to improved mood, better attention span, and reduced stress levels, leading to better overall mental performance. With its combination of natural ingredients that are backed by scientific research, Feedamind provides a wholesome solution to anyone looking for an effective nootropic supplement that offers a wide range of cognitive benefits.

4. Mind Lab Pro

Mind Lab Pro is a high-quality nootropic supplement that has gained popularity among professionals, students, and athletes who seek to enhance their cognitive performance. This unique nootropic pill contains 11 scientifically proven brain-boosting ingredients, making it one of the most powerful and comprehensive nootropic solutions in the market.

The reason for Mind Lab Pro’s widespread appeal is the absence of severe stimulants, ensuring that users can take the supplement without experiencing jitters or other major side effects. Its formula is non-GMO and vegan, making it suitable for a wide range of individuals seeking a natural cognitive enhancer.

Some of its key ingredients include L-Theanine, Bacopa Monnieri, Citicoline, Lion’s Mane Mushroom, B vitamins, Phosphatidylserine, Maritime Pine Bark Extract, N-Acetyl-L-Tyrosine, and Rhodiola Rosea, which work together to promote cell membrane production, provide neuroprotective benefits, and help the body adapt to stress.(6)(7)


  • Enhances memory and focus
  • Works against depression and anxiety
  • Improves mental and physical energy


  • Some users may not feel significant effects
  • May cause headaches or nausea in some users

The comprehensive blend of nootropics in Mind Lab Pro targets different brain processes, providing a well-rounded boost in cognitive abilities. With its extensive benefits, Mind Lab Pro remains an excellent choice when looking for an effective and safe nootropic supplement to improve brain health and cognitive performance.

5. Caffeine

Caffeine is a well-known and popular natural nootropic that can be found in many daily beverages, such as coffee, tea, and energy drinks. As the most widely consumed psychoactive substance in the world, caffeine provides a noticeable boost in alertness, attention, and focus while also decreasing reaction time. With a low-to-moderate caffeine intake of 40-300 mg, individuals can experience these benefits, making it especially effective for those who are fatigued or experiencing a lack of energy.(8)

While it may be consumed through natural sources, caffeine is also available in supplement form, either on its own or in combination with other nootropic substances. One such combination is with L-theanine, an amino acid found in tea, which has been shown to have a calming effect without causing drowsiness and may even increase creativity. The combination of caffeine and L-theanine allows for enhanced focus and alertness without the jittery side effects that caffeine may cause when consumed in high doses.


  • Increases energy levels and alertness
  • Improves physical performance
  • Helps with weight loss
  • Improves mood and reduces fatigue


  • Can lead to addiction and withdrawal symptoms
  • Can cause jitters, anxiety, and sleep disturbances
  • Can interfere with nutrient absorption and hormonal balance
  • Can be harmful in excessive amounts or for certain individuals with medical conditions

In summary, caffeine is a widely accessible and easy-to-use nootropic option that can lead to noticeable improvements in alertness and cognitive performance, especially when combined with other complementary substances.

How Do Nootropics from GNC Work?

Nootropics at GNC work by enhancing various aspects of cognitive function, such as memory, focus, and mental clarity. These supplements typically contain a combination of natural ingredients, such as amino acids, vitamins, minerals, and herbal extracts, that have been scientifically proven to support brain health and improve mental performance.

One of the most common ways that nootropics at GNC work is by boosting the production of neurotransmitters, such as dopamine and serotonin, which play a crucial role in regulating mood, motivation, and concentration. Some nootropics may also improve blood flow to the brain, providing it with essential oxygen and nutrients for optimal function.

In addition to supporting overall brain health, GNC nootropics may have specific benefits for individual cognitive functions. For example, they may improve memory retention and recall by enhancing the process of synaptic plasticity, which is crucial for the formation and storage of new memories. Similarly, nootropics at GNC may enhance focus and attention by increasing the production of brain chemicals that help regulate these cognitive functions.

To experience the full benefits of nootropics at GNC, it is essential to follow the recommended dosage and usage instructions. Consistent use of these supplements, combined with a healthy lifestyle and proper nutrition, can lead to noticeable improvements in cognitive performance over time.

What to Consider Before Buying Nootropics at GNC?

Before purchasing nootropics from GNC, it’s essential to weigh several considerations to make an informed decision:

1. Personal Health and Sensitivities

Understanding your health status and any sensitivities is vital. Nootropics can interact with certain health conditions and sensitivities, thus individual health must guide your choice.

2. Desired Cognitive Benefits

Different nootropics target various aspects of cognition. Identifying the specific cognitive functions you wish to enhance will help narrow down your options.

3. Synergy with Lifestyle and Diet

Your current lifestyle and diet can influence the effectiveness of nootropics. Consider how the supplement will fit into your daily routine.

4. Potential Interactions with Medications

If you are currently taking medication, it’s crucial to understand how nootropics may interact with these substances.

5. Reviews and Testimonials

Real user experiences can provide insight into the efficacy and potential side effects of the nootropic supplements you’re considering.

How We Picked the Top Nootropics at GNC

We used a comprehensive review process to identify the best nootropics available at GNC. We took into account effectiveness, ingredients, brand reputation, transparency, manufacturing process, user feedback, price, and value. By evaluating these factors, we were able to present our readers with a reliable list of the top nootropic supplements found at GNC.


We reviewed clinical trials and user experiences to measure cognitive enhancements, specifically focusing on memory, focus, and mental processing speed.


We examined each formula, prioritizing evidence-based, natural, and high-quality ingredients that improve cognitive function.

Scientific Evidence

We consulted peer-reviewed studies and meta-analyses to confirm the effectiveness of key ingredients in promoting cognitive performance.


We evaluated optimal dosages and ingredient ratios, ensuring they were in line with established research for maximum benefits.


We confirmed the safety of each ingredient, considering potential side effects, interactions, and compliance with regulatory guidelines. We prioritized FDA-approved ingredients.

Brand Reputation

We assessed the credibility and trustworthiness of brands available at GNC through customer reviews, expert endorsements, and company history.

Product Transparency

We valued comprehensive ingredient disclosure, including ingredient sources and concentrations, to support informed consumer decision-making.

Manufacturing Process

We inspected manufacturing standards, giving preference to products made in certified facilities and adhering to Good Manufacturing Practices (GMP).

User Reviews

We analyzed genuine customer feedback, placing emphasis on testimonials that detailed cognitive enhancement and mental performance improvements.


We compared the prices of available nootropics at GNC, ensuring they were competitive and correlated with the quality and efficacy of the supplement.


We appraised overall value, taking into account the balance of price, quality, and effectiveness to ensure the best return on investment for consumers.

Nootropics for GNC in Summary

In summary, nootropics, also known as smart drugs or cognitive enhancers, have gained significant popularity in recent years due to their potential to improve memory, focus, and overall cognitive function. Although several nootropic supplements are available on the market, it is crucial to carefully select the most effective and safe options based on scientific research and clinical studies.

Among the top choices at GNC, you’ll find products like Vyvamind, NooCube, and Feedamind, which are designed for improved cognitive performance through enhancing neurotransmitter levels and supporting brain health. Mind Lab Pro is another highly recommended option, as it not only addresses cognitive function but also promotes relaxation and mood enhancement. Finally, you can’t forget about caffeine, a classic nootropic that can easily be found at GNC in various forms, such as pills and energy drinks.

It’s important to note that these nootropics may not be as potent or specialized as some alternatives offered by dedicated nootropic retailers. However, they can still provide a noticeable boost in mental performance for those who wish to explore the benefits of nootropics without diving too deeply into the world of cognitive enhancement just yet.

Ultimately, selecting the best nootropic supplements involves carefully considering the safety, efficacy, cost, and convenience of each option. By conducting thorough research and consulting with healthcare professionals, individuals can make informed decisions to enhance their mental performance and overall well-being.

FAQs About Nootropics at GNC

Are nootropics available at GNC safe?

Nootropics are generally considered safe, but the safety of individual ingredients can vary. It is recommended to consult a healthcare provider before starting any new supplement, and to choose nootropics with research-backed and clinically proven ingredients.

Are there any side effects to taking nootropics from GNC?

Some nootropics may cause mild side effects such as headaches, dizziness, or nausea. Be sure to follow the recommended dosage and consult a healthcare provider if you experience any adverse effects.

How long does it take for GNC nootropics to work?

The time it takes for a nootropic to show effects can vary depending on the individual and the specific supplement. Some nootropics may show results in as little as a few hours, while others may take weeks of consistent use for noticeable benefits.

Can nootropics from GNC be taken with other medications?

It is important to consult with a healthcare provider before combining nootropics with other medications, as there may be potential interactions or contraindications.

Sources, Studies, and Scientific Research
  1. Adibhatla, Rao Muralikrishna, J. F. Hatcher, and R. J. Dempsey. “Citicoline: neuroprotective mechanisms in cerebral ischemia.” Journal of neurochemistry 80.1 (2002): 12-23. ↩
  2. Parker, Adam G., et al. “The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility.” Journal of the International Society of Sports Nutrition 12.sup1 (2015): P41. ↩
  3. Li, Jun, et al. “Huperzine A for Alzheimer’s disease.” Cochrane Database of Systematic Reviews 2 (2008). ↩
  4. Roodenrys, Steven, et al. “Chronic effects of Brahmi (Bacopa monnieri) on human memory.” Neuropsychopharmacology 27.2 (2002): 279-281. ↩
  5. Lopez, C. M., et al. “Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine.” Pharmacology Biochemistry and Behavior 39.4 (1991): 835-840. ↩
  6. Vance, Jean E., and Rineke Steenbergen. “Metabolism and functions of phosphatidylserine.” Progress in lipid research 44.4 (2005): 207-234. ↩
  7. He, Xirui, et al. “Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion’s Mane) mushroom: A review.” International journal of biological macromolecules 97 (2017): 228-237. ↩
  8. Beck, Travis W., et al. “The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.” The Journal of Strength & Conditioning Research 20.3 (2006): 506-510. ↩