9 Best Nootropics on Amazon 2023 (Smart Drugs & Brain Supplements)

Updated on August 14, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
best nootropics on amazon

What are the best nootropics on Amazon?

Do you ever feel like your brain needs a boost? Maybe you struggle with concentration, memory, or mental clarity.

If so, you've probably heard of nootropics, also known as smart drugs or brain supplements. These supplements are becoming increasingly popular, and for good reason – they help improve cognitive function, creativity, and even mood. But with so many options out there, it can be tough to know where to start.

That's why we've put together a list of the best nootropics on Amazon, so you can upgrade your brain without breaking the bank.

Best Nootropics on Amazon

1. Alpha Brain

Onnit Alpha Brain is one of the best nootropics available on Amazon. It is a brain supplement that contains powerful ingredients such as Phosphatidylserine, L-Theanine, Alpha GPC, and Huperzine A. These ingredients have been scientifically proven to enhance memory, focus, and overall cognitive function. Alpha Brain is stimulant-free, vegan, and non-GMO, making it a perfect choice for those who prefer natural and plant-based supplements. 

What sets Alpha Brain apart from other nootropics is its high potency and effectiveness. Many users report improved memory retention, increased mental clarity, and enhanced productivity after taking Alpha Brain. It is also worth noting that Alpha Brain has received positive reviews and recommendations from experts in the field of nootropics. 


  • Enhances cognitive performance
  • Improves focus and concentration
  • Supports memory and learning
  • Promotes better sleep and lucid dreaming


  • Requires daily intake for optimal effects
  • Potential for mild side effects such as headaches or digestive issues
  • Not suitable for pregnant women or individuals with certain medical conditions

With Alpha Brain, you can trust that you are getting a safe and reliable nootropic supplement that can help boost your brain performance.

2. Qualia Mind

Qualia Mind is a top brain supplement that is available on Amazon as it effectively supports memory, focus, mental energy, and concentration. This powerful nootropic contains ingredients such as Ginkgo biloba, Alpha GPC, Bacopa Monnieri, DHA, and more. Qualia Mind and its ingredients' efficacy is backed by reputed research studies. People like Jason Silva, Ben Greenfield, and Dr. Daniel Stickler trust Qualia Mind to help them perform at their best. 

What sets Qualia Mind apart is its precision-dozed formulation and carefully sourced ingredients. It is free from artificial colors, flavors, and sweeteners. It is also gluten-free, vegan, and non-GMO. Qualia Mind helps replenish vital ingredients required for high-level cognition and to promote clear-headed cognition and a positive mood. Plus, it comes with a 100-day money back guarantee, so you can try it risk-free.


  • Provides comprehensive cognitive support
  • Enhances mental clarity and focus
  • Improves overall brain health and function


  • Potential for mild side effects such as gastrointestinal discomfort
  • Not recommended for individuals with certain medical conditions

If you're looking for a brain supplement that supports memory, focus, and mental clarity, Qualia Mind is a top choice on Amazon.

3. Mind Lab Pro

Mind Lab Pro is a top-rated nootropic supplement available on Amazon. It stands out among other nootropics because it combines the best ingredients in a comprehensive cognitive health stack. With Mind Lab Pro, you can experience enhanced focus, memory, clarity, and energy. It aims to unlock maximum brainpower and provides a mental performance state that "fires on all cylinders." The supplement helps to get rid of brain fog and mental burnout, while also boosting brain circulation and plasticity. The ingredients in Mind Lab Pro promote calm alertness, improved productivity, and brain health in the long run.


  • Enhances cognitive performance across multiple areas
  • Supports memory, focus, and mental clarity
  • Promotes overall brain health


  • May take some time to notice noticeable improvements
  • Not recommended for pregnant or nursing women, or individuals with certain medical conditions

This nootropic supplement contains natural, plant-based ingredients that are easily absorbed by the body. It is gluten and lactose-free, and does not contain GMOs, caffeine, or synthetic additives. With Mind Lab Pro, you can fuel your brain with the best nootropics available on Amazon.

4. TruBrain

TruBrain is a popular nootropic supplement that aims to improve focus, energy, and clarity. It contains a blend of ingredients that enhance brain function and support mental performance. TruBrain is formulated by neuroscientists and contains several potent nootropics, including mushrooms, which are known for their cognitive-enhancing properties. The supplement is available in capsule form, as well as in a conveniently packaged drink. TruBrain claims to enhance oxygen and blood flow in the brain, allowing it to power through tasks more effectively. It is also said to help reduce mental blocks, increase verbal fluency, and improve memory.


  • Enhances focus, memory, and mental clarity
  • Promotes calmness and removes anxiety


  • Some users may experience a crash or jitters
  • Not recommended for individuals with certain medical conditions

TruBrain prides itself on being a small business brand, and their products are available for purchase on Amazon. While TruBrain has received positive reviews from customers, it's important to note that individual results may vary.

5. Rhodiola Rosea

Rhodiola Rosea is a natural supplement derived from the herb that has gained popularity for its potential to enhance brain function. It is often used in Chinese medicine to promote well-being and reduce fatigue. Studies have shown that people who take Rhodiola Rosea experience a decrease in fatigue and improvement in their brain function.(1) This supplement works by reducing tiredness, which in turn helps improve thinking skills. However, it is worth noting that more research is needed to fully understand the effects of Rhodiola Rosea on brain function.

Rhodiola Rosea may be a beneficial option for individuals looking to enhance their mental performance and reduce fatigue. However, it is important to note that individual results may vary, and this supplement may not be effective for everyone. It is always recommended to consult with a healthcare professional before starting any new supplement regimen.


  • Improves mood and reduces stress
  • Enhances mental performance and focus
  • Promotes physical and mental resilience


  • Potential for mild side effects such as insomnia or agitation
  • Not recommended for individuals with bipolar disorder

Overall, Rhodiola Rosea offers potential benefits for brain health and can be a natural way to support mental clarity and focus. With its positive effects on fatigue reduction, it may be a useful addition to a comprehensive approach to cognitive wellness.

6. Caffeine

Caffeine, a commonly consumed stimulant, is not only found in your morning cup of coffee but is also available as a nootropic on Amazon. This natural compound has been known to enhance cognitive performance, improve focus, and increase alertness. Consuming caffeine stimulates the central nervous system, blocking the activity of adenosine, a neurotransmitter that promotes relaxation and drowsiness. By doing so, caffeine can make you feel more awake and focused.

Furthermore, caffeine has been shown to increase dopamine production, a neurotransmitter associated with pleasure and reward.(2) This can lead to improved mood and motivation. Additionally, caffeine can enhance physical performance by increasing adrenaline levels, which can improve endurance and reduce fatigue.

However, it's important to be mindful of your caffeine intake and consume it in moderation. Excessive consumption can lead to negative side effects such as jitters, increased heart rate, and difficulty sleeping. It's also worth noting that the effects of caffeine can vary from person to person, so it's important to find the right dosage for you.


  • Enhances alertness and energy levels
  • Improves focus and concentration
  • Increases metabolism and physical performance
  • Has positive effects on mood and cognitive function


  • Can cause jitters, anxiety, or insomnia in high doses
  • Tolerance can develop with prolonged use

Overall, caffeine can be a beneficial addition to your daily routine if used responsibly. So why not give it a try and see how it can boost your cognitive performance and help you stay alert throughout the day?

7. Lion's Mane Mushroom

Lion's Mane Mushroom is one of the best nootropics you can find on Amazon. It's a powerful brain-boosting supplement that can optimize cognitive performance and promote mental clarity, focus, and memory. This natural and organic supplement is highly rated and has received positive feedback from customers.

One of the great things about Lion's Mane Mushroom is its ability to support brain health. It contains compounds that can stimulate the production of nerve growth factor (NGF), which is essential for the growth and maintenance of neurons. By increasing NGF levels, Lion's Mane Mushroom enhances brain function and improves cognitive abilities.(3)

Additionally, Lion's Mane Mushroom has been found to have anti-inflammatory properties and can help protect the brain against neurodegenerative diseases.(4) It can also boost mood and reduce symptoms of anxiety and depression.


  • Enhances memory and focus
  • Promotes nerve regeneration
  • Has mood-lifting effects and supports overall well-being


  • Potential for mild gastrointestinal discomfort
  • Requires consistent use for optimal effects

If you're looking for a natural and effective way to improve your brain health and cognitive function, Lion's Mane Mushroom is definitely worth considering. With its numerous benefits and positive reviews, it's no wonder why it's one of the best nootropics available on Amazon.

8. Phosphatidylserine

Phosphatidylserine (PS) is a fascinating nootropic supplement that has shown promising benefits for brain health. It is a type of fat compound known as a phospholipid, which is naturally found in your brain. Taking PS supplements preserves brain health and enhances cognitive function.

Research has shown that PS supplements can help combat age-related decline in brain function. In one study, taking 100 mg of phosphatidylserine three times a day resulted in improved thinking skills and memory in healthy individuals.(5) Another study found that healthy people who took up to 400 mg of PS per day experienced improved cognitive function.(6)

While these findings are promising, it is important to note that larger studies are needed to fully understand the effects of PS on brain function. Nevertheless, these initial results suggest that PS supplements could be beneficial in supporting brain health and delaying cognitive decline associated with aging.


  • Supports memory and cognitive function
  • Helps combat age-related cognitive decline
  • Has mood-stabilizing effects


  • Not recommended for individuals with certain medical conditions

It is worth considering adding phosphatidylserine to your nootropic stack if you are looking for a natural way to support your brain health. As always, it is advisable to consult with a healthcare professional before adding any new supplement to your routine.

9. Bacopa Monnieri

Bacopa Monnieri is one of the best nootropics available on Amazon for enhancing brain function. This natural herb has been used for centuries in Ayurvedic medicine for its cognitive benefits. Bacopa Monnieri works by increasing blood flow to the brain, which improves memory, focus, and overall cognitive performance.(7)

In addition to its brain-boosting properties, Bacopa Monnieri is also known for its adaptogenic effects. This means that it helps the body adapt to stress and promotes a sense of calm and relaxation. Many people find that taking Bacopa Monnieri supplements helps them stay focused and productive, even in stressful situations.


  • Supports memory and learning
  • Enhances focus and concentration
  • Has mood and stress reduction effects


  • Requires consistent use for optimal effects
  • Not recommended for pregnant or nursing women

Overall, Bacopa Monnieri is a natural and effective nootropic that can enhance brain function and improve cognitive performance. Its adaptogenic properties also make it a great option for managing stress and promoting a sense of calm and focus.

How Do Nootropics on Amazon Work?

Nootropics sold on Amazon are cognitive enhancers that work by improving various aspects of mental function. These supplements contain ingredients that have been shown to positively impact focus, mood, memory, and energy levels. The nootropics available on Amazon range from single-ingredient pills to comprehensive multi-ingredient stacks.

While Amazon sells both natural and synthetic nootropics, they primarily offer supplements with safe and natural ingredients. They refrain from selling controversial cognitive enhancers that may have risky effects. When buying nootropics on Amazon, it is important to consider factors such as the Amazons Choice and Best Seller tags, which indicate the endorsement or popularity of a product.

However, customer reviews should be taken with caution as they can be easily manipulated. Despite the convenience and wide selection of nootropics on Amazon, it can be challenging to differentiate the best quality supplements from the rest. Mind Lab Pro is not sold on Amazon but offers a wealth of information on their website regarding the best-in-class ingredients used in their nootropic stack.

How We Picked the Top Nootropics on Amazon

Our approach to identifying the best nootropics on Amazon involved an in-depth analysis of multiple factors, including effectiveness, formulation, brand reliability, transparency, manufacturing process, customer responses, cost, and overall value. We meticulously examined each of these elements to offer our readers an authoritative and comprehensive list of the top-performing nootropics available on Amazon.


We studied clinical studies and user testimonies to measure cognitive enhancement, with particular emphasis on memory, attention, and mental speed.


Each product's formula was closely examined, with special emphasis on proven, natural, and high-grade ingredients that boost cognitive function.

Scientific Backing

The efficacy of primary ingredients in boosting cognitive functions was corroborated using peer-reviewed research and meta-analyses.


We evaluated optimal dosages and ingredient proportions, ensuring conformity with relevant scientific research for peak efficacy.


Each ingredient's safety was confirmed by considering potential side effects and interactions, and ensuring compliance with regulatory standards. Preference was given to ingredients approved by the FDA.

Brand Reliability

Brands' credibility and trustworthiness were gauged through customer ratings, professional recommendations, and the company's track record.

Product Transparency

We valued full disclosure of ingredients, including their sources and strengths, to promote educated consumer choices.

Manufacturing Process

We scrutinized the manufacturing standards, prioritizing products made in certified facilities that adhere to Good Manufacturing Practices (GMP).

Customer Responses

We analyzed authentic customer reviews, giving importance to feedback that mentioned cognitive enhancement and other improvements.


We compared the prices of products, ensuring that they were competitive and proportional to the quality and effectiveness of the nootropic.


We evaluated the overall value, considering the balance of cost, quality, and efficacy to ensure the best possible return on investment.


We have discussed the nine best nootropics available on Amazon. These smart drugs and brain supplements are known for their cognitive benefits, including improved focus, memory, learning, motivation, and more.

The top nootropics on Amazon include Alpha Brain, Qualia Mind, Mind Lab Pro, TruBrain, Rhodiola Rosea, Caffeine, Lion's Mane Mushroom, Phosphatidylserine, and Bacopa Monnieri.

We also discussed how nootropics work, and how we selected the top nootropics for this list. Nootropics are dietary supplements that provide cognitive benefits by supporting brain health and function. They can be effective for anyone looking to enhance their brain function, from students and professionals to athletes and senior citizens.

Our selection process for the top nootropics on Amazon involved considering factors such as ingredients, dosage, customer reviews, price, and effectiveness.

In summary, if you're looking to enhance your cognitive function and improve your overall brain health, these nootropics available on Amazon can be a great option for you.


Are nootropic supplements safe to buy on Amazon?

Nootropic supplements are safe when used responsibly. However, there is a chance for abuse, so it's crucial to follow recommended dosages and not exceed them. It's also important to consult with a healthcare professional if you are taking prescription medications or have any underlying health conditions.

Is it legal to buy nootropics on Amazon?

Nootropics are legal in the United States, but laws may differ from one country to another. It's important to note that purchasing restricted medications without a valid prescription is against the law. Natural nootropics are usually available as over-the-counter supplements and are not subject to regulation.

How can I ensure that I am buying quality nootropic supplements on Amazon?

There may be some low-quality junk products listed on Amazon that claim to be nootropic supplements. To ensure that you are buying quality nootropic supplements on Amazon, it's important to read the product description and do your research on the manufacturer. Additionally, checking Amazon customer reviews can be helpful in determining the quality of the product.

Are the nootropics on Amazon FDA approved?

Nootropics are dietary supplements and do not require FDA approval, but should be manufactured in an FDA registered facility.