Bromantane: Review, Where to Buy, Dosage & Side Effects

Whether you suffer from depression, anxiety, or lack of focus and declining stamina during workouts, you may have looked for a supplement that can give a little extra kick to keep you going.

Bromantane promises to provide that kick, helping you clear the effects of depression and fatigue and keeping your brain more on task to improve overall performance.

But what is it exactly and how does it work?

How do you use it, and what sort of side effects can you expect, if any?

In this Bromantane review, we’ll look at it in-depth, provide a few tips on its usage, and discuss where you can buy it.

What Is Bromantane?

chemical structure

Bromantane [R] — also known as Ladasten or NP-160 — is a nootropic drug that is a synthetic adaptogen (actoprotector) shown improvement of mental and physical performance throughout the body by helping the brain increase and regulate neurotransmitters. It's classified as a mild stimulant and can help with chronic kidney disease (CKD) and idiopathic pulmonary fibrosis (IPF).

In the 1980s, Russian scientists developed Bromantane, which led to improved performance of workers under environmental stressors like heat. The drug enabled workers to focus better with greater motivation, effectively increasing physical work capacity. It's also approved and used for treating asthenic disorders such as neurasthenia in Russia.

Nootropics as a group are commonly known as ‘smart drugs’ because of the way they operate in the brain.

According to clinical research, Bromantane works through stimulating increased activity in the hippocampus, the area of the brain that controls and regulates the production of neurotransmitters such as dopamine and serotonin [R]. Unlike most typical psychostimulants, it's been found to also exert anxiolytic effects as well as a decreased toxic effect of certain agents in rats. Its anxiolytic effect can be contributed to its ability to strentghen GABA-ergic mediation while reducing gene expression. Its positive influence on the immune system is also well-documented.

Bromantane is an adamantane derivative, which has a variety of uses in chemical, medical, and even industrial fields due to its unique, stable structure.

Similar to typical stimulants, the benefits of the smart drug include its positive effect on energy, dopamine reuptake by increasing tyrosine hydroxylase, reduction of anxiety (see Eksp Klin Farmakol in Russian), better coordination, and better concentration on tasks by helping increase serotonin production and use, resulting in an overall improvement of mental performance even under extreme conditions and physical loads without increasing oxygen consumption.

However, regulators at the Food and Drug Administration (FDA) in the United States haven’t fully approved Bromantane yet.

Clinical trials continue on to-be-proved benefits, but the Olympic committee banned Bromantane use in professional athletes, which disqualified many Olympians from Russia for the foreseeable future.

How To Take Bromantane

Bromantane comes either in simple capsule form or powder form. Ladasten pills come in 25 mg doses that are easy to swallow, but you should take it with meals. It’s best to start slow and take no more than the recommended dosage, as discussed below.

Women metabolize and absorb Bromantane faster than men, so they may need a larger dose to get the same results. Take care not to take it just before bed, as it can result in interrupted sleep due to the high energy and mental acuity it causes.

You want to be relaxed before heading to sleep, and Bromantane (also known as ADK-709) can interfere with that goal.

Even a single treatment with Bromantane has resulted in an increase in spontaneous motor activity.


As with any drugs, getting the dosage right and figuring out what works for you is an essential step in taking full advantage.

When it comes to new drugs that you aren’t used to, take it slow and see how you react to them under different conditions. Most Bromantane capsules come in amounts of 25 milligrams (mg), so start with one per day for a while to determine how you respond to it.

If you bought the powder form, start with 25 mg as well.

As we mentioned above, women metabolize Bromantane faster, so they may want to adjust the initial dose to 50 mg as they test its effectiveness.

In very high doses it has been found to produce anticholinergic effects in experimental animals. Although this isn't relevant for common clinical doses, it therefore makes sense to stack it with a Choline source such as CDP Choline or Alpha GPC.

Side Effects

Without comprehensive human trials, it’s hard to say what sort of side effects you might experience at what dose, aside from anecdotal evidence and a few animal studies.

Bromantane is also non habit-forming, so you don't have to worry about addiction or withdrawal.

The few adverse effects of Bromantane listed might sound counterintuitive considering the intended action of it. But they include fatigue, brain fog, depression, and confusion. In studies with lab mice at a very high doses, diarrhea, vomiting, and insomnia occurred, which is another good reason to stick to recommended amounts.

As we mentioned above, don’t take it before bed. It ramps up brain activity, making it difficult to sleep. Most people report no side effects at all. But when they do experience any, they feel the energy boost suddenly wearing off, causing a sudden crash.

Reviews & Experiences Shared On Reddit

Here is a sample of customer reviews taken from Reddit:

  • "felt great. Calm, motivated, a very subtle kind of euphoric happy mood throughout the day. I was wide awake, and very sociable. I held a conversation for almost 3 hours with a coworker who I'd hardly ever talked to!"
  • "…my anxiety completely disappeared, confidence appeared, and now it is easier for me to concentrate, this is an amazing combination, I also had a very depressed state for a long time, negative thoughts in my head disappeared."
  • "Instantly improves mood (i have a very hard depression), helps with ADHD, adds energy and motivation. And most importantly makes me very sociable and self-confident. With this drug, you feel better than everyone."

Where To Buy Bromantane Powder

There are many online websites offering places to buy Bromantane.

But the best we’ve found is, which provides 5 grams of Bromantane in powder form for a very reasonable price.

They also offer a terrific shopping experience in an accessible layout for a variety of other nootropic supplements.

Don’t expect to find Bormantane at your local natural supplements shop - it's only sold online.

Frequently Asked Questions (FAQs)

Your questions answered.

Is There A Recreational Use For Bromantane?

Bromantane has no actual 'high,' and it isn't habit-forming. It improves brain function and helps people keep focus and concentration on tasks while helping alleviate anxiety and depression, so there isn't necessarily a 'recreational' use as it's commonly understood.

Is Bromantane Good For ADHD?

Because many of the alleged benefits of Bromantane have yet to be verified, it's hard to say with any certainty that it works to manage ADHD symptoms. You can refer to anecdotal evidence compiled by users.

Does Sublingual Administration Make Sense?

Yes, you can take Bromantane sublingually to increase its effectiveness.

How Do I Make Bromantane Solution?

You can just buy Bromantane solution to spare yourself the trouble.

How Long Does It Take To Work?

The acute effects of Bromantane have a gradual onset over 1 to 2 hours and last for 8-12 hours.

What's Its Half-Life?

The elimination half-life of Bromantane in humans is about 11.5 hours.


Bromantane, or Ladasten, is an exciting nootropic drug that shows a lot of promise to mitigate a wide variety of mental issues such as depression, anxiety, and possibly even ADHD.

By increasing dopamine production and helping to regulate serotonin receptors, it provides a framework for focused action, whether it's staying alert and active throughout a repetitive task like assembly line work, working out at the gym, or even studying for a test.

Unfortunately, the United States' FDA hasn't tested or approved Bromantane for general use, so many of its claimed benefits come from anecdotal evidence and the work of the Russian scientists who developed it.

Bromantane is an officially banned performance enhancement through the International Olympic Committee, but that only serves to add legitimacy to its claims, so long as you're not a professional athlete.