Pramiracetam Review: Dosage, Benefits, Side Effects & Buy

Trying to remember everything about what your boss told you is a task for Pramiracetam.

You may have problems recalling school lessons, or you may have been under brain trauma treatment.

If so, you too can dive into this review and learn how this cognitive-enhancing power pill works with wonderful effects on your brain.

Read on and look closely at the brain-boosting capabilities of Pramiracetam.

What is Pramiracetam?

pramiracetam structure

Pramiracetam [R] was synthesized in 1979 by the Parke-Davis pharmaceutical company and was distributed as Primastar.

Similar to Piracetam, it is known for its cognitive-enhancing properties but works up to 30 times stronger.

The supplement was initially developed for patients suffering from neurodegenerative disorders, brain injuries, and other central nervous system disorders.

Pramiracetam is a positive allosteric modulator of the AMPA receptor. It has been studied for its role in memory enhancement, neuroprotection, and mood improvement.

This nootropic is becoming widely known in the US and some countries in Europe. People use it as a supplement to improve mental capabilities such as the formation, processing, and retrieval of information. It is also able to stimulate concentration and focus.

Imagebuy pramiracetam powder online
EffectsEnhances memory, provides neuroprotection, increases blood flow and oxygen to the brain
Potential Side EffectsHeadache, dry mouth, vertigo, nervousness
Half-Life4 - 7 hours
Common Dosage500 - 800 mg daily
Content5 g
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Even though it is created for the elderly and brain-injured patients, healthy people also flock to get their hands on the pills.

Mechanism of Action

Pramiracetam is a racetam supplement of the 2-oxo-pyrrolidine class, which contains a piperidine group. This unique feature gives the compound different properties from its close relatives, such as Piracetam and aniracetam.

In addition, unlike Piracetam, Pramiracetam shows a high affinity for both synaptic and extrasynaptic AMPA receptors in rat forebrain membranes but no affinity for NMDA or kainate receptors.

Pramiracetam binds to the PSB site in rat brain membranes with a K i = 9–17 μM.

What is the Use of Pramiracetam?

Pramiracetam was synthesized from Piracetam as a drug to enhance mental capacity through the high-affinity choline uptake (HACU) process.

pramiracetam review

Affects memory

It was developed to prevent memory loss among the elderly and aid in treating patients who are suffering from neurodegenerative diseases.

After several years, its potential as a neuroenhancer was tested among humans - young and healthy - whether or not they have brain-related health conditions.

As a result, it was recorded as a nootropic that significantly increased retention and reduced symptoms of mild amnesia.


Pramiracetam is a drug that is used to protect the brain against various types of damage. It helps to stimulate mental activity and boosts memory. Doctors can prescribe this particular medication to people who suffer from seizures.

Pramiracetam has also been extensively studied for its potential treatment for Alzheimer's disease, Parkinson's disease, stroke recovery, depression, and more.

Pramiracetam boosts memory, mental activity, and it is an excellent neuroprotector. It is believed to have a very high potency due to its superior lipid solubility, allowing it to cross the blood-brain barrier.

Recovery from Brain Injury

Many European countries prescribe this supplement to help treat neurological conditions. This is not limited to the elderly because it is also used among adults suffering from ADHD, dyslexia, and dementia [R].

Pramiracetam is a nootropic drug that helps in the prevention and treatment of neurological diseases and disorders. It is also effective in improving cognitive performance and reducing brain damage caused by head injuries .

Effects & Benefits of Pramiracetam

Using Pramiracetam is famous not just as a treatment in the medical field. Pramiracetam reviews also show that it is used as a supplement among healthy young individuals.

Among the positive benefits of taking the pill are the following:

Increases recall. Research magnifies its essential role in dramatically enhancing memory. It targets the hippocampus part of the brain and ensures high memory functions and better learning ability.

Provides neuroprotection. This is one benefit that addresses the potential damage caused by toxins and other drugs like scopolamine, which produces memory loss. A partial reduction of the case was recorded, slowing down a person's cognitive decline.

effects of pramiracetam

Speeds up brain injury recoveries. When the brain suffers from injury or trauma, large doses of drugs are often administered for fast recovery. Since Pramiracetam is 30 times stronger than other nootropics, a fewer dose is just what it needs to help reduce the side effects of mild neurological injuries.

Improves memory loss. The adequate blood supply in the brain ensures better memory, but when the arteries supplying the blood are blocked, it poses negative cognitive symptoms. Patients who have Pramiracetam experience attested to have an improved memory after several weeks of treatment.

So is there any scientific evidence indicating the positive effects of Pramiracetam?

Yes. Studies have shown that Pramiracetam significantly enhanced cognition and mood in older adults with memory impairment. A separate study showed that people who took 300 milligrams of Pramiracetam experienced improvements in visual information processing, spatial planning ability, and associative learning.

It has also been used to prevent neurodegeneration due to its neuroprotective properties and improve cognitive function in healthy individuals.

Although it has some relatively minor side effects such as headache and nausea, these issues can likely be overcome by adjusting the dosage or taking pills instead of powder for the supplement.

How Does It Work in the Brain?

Pramiracetam maintains and increases the blood flow and oxygen being carried to the brain while ensuring a stabilized glucose metabolism.

It stimulates the chemicals through an increased choline level or high-affinity choline uptake to have better brain activity. Choline plays a vital role in kick-starting the acetylcholine receptor, which functions as a neurotransmitter in the hippocampus. With enough choline, mental energy reaches its potential in storing and recalling long and short-term memories.

Clinical trials have shown that the overall cognitive abilities of the brain are enhanced while getting an adequate supply of blood and oxygen.

Dosage of Pramiracetam

The most advisable dose is between 500-1600 mg, split into several doses.

In taking Pramiracetam, start with the minimum dose of 500 mg spread throughout the day. You can increase your intake once your body gets used to the drug. It is also advised to take it during the day and preferably after a meal.

The optimal dose of Pramiracetam is 600 mg per day, taken in two doses. Some users take as much as 1 g per day. Still, it's important to note that many experts believe this dangerous due to potential side effects such as increased agitation and irritability.

Be mindful not to exceed your daily dose by taking too many other nutritional supplements containing Pramiracetam or any racetams. An overdose could result in poisoning.

At a dosage of 600 milligrams a day, Pramiracetam has been shown to increase cognition and improve the mood at a safe dosage.

How to Take Pramiracetam?

You can choose to take the Pramiracetam powdercapsule, or tablet form. It is advised to spread the dose throughout the day and every after a meal to get the maximum effects of the nootropic.

how to take pramiracetam

Side Effects

Pramiracetam is a low-risk nootropic that requires a fewer dose compared to other nootropics. Taking a higher dose would only result in intolerance.

Even if you are only taking the small dosage, you may still feel very few side effects that are very common to nootropics.

Pramiracetam is usually well-tolerated, but some people experience mild side effects such as headache, insomnia, nausea, and irritability at higher doses.

Pramiracetam increases dopamine levels in the brain, leading to agitation and anxiety in some users of the supplement. It's unclear why this happens for some people and not others, so be mindful of any adverse changes you experience when taking pramiracetam supplements.

If you notice signs of anxiety or irritability even after stopping the use of pramiracetam supplement, consult your doctor immediately.

How to Reduce Side Effects

Pramiracetam is a beautiful nootropic that should be part of any stack of drugs, but it can also cause some side effects in users. The most common side effect is headaches, but insomnia, dry mouth, vertigo, nervousness, stomach discomfort, nausea, and constipation are also reported by some users.

side effects of pramiracetam

Fortunately, there are ways to reduce Pramiracetam's side effects for people who suffer from these symptoms.

Taking this smart drug with meals instead of on an empty stomach will help reduce many people's nausea and discomfort. Drinking plenty of water along with Pramiracetam can also help ease dry mouth and constipation.

Pramiracetam should be taken in the morning or early afternoon, not late at night, as insomnia is a potential side effect.

The severity of each side effect is different for every person, but if none of the tips mentioned above help, then it's best to stop taking this smart drug or talk with your doctor about alternative options.

Experiences Shared on Reddit

Here's what the users have to say about this smart drug.

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Pramiracetam Stacks

The typical downside of taking nootropics is the reduction of choline.

pramiracetam stack

Let us not forget that choline plays an important role in sending signals to the brain. It is the precursor of acetylcholine, a neurotransmitter and the one that does all the sending of signals.

Pramiracetam stack is popular to ensure better well-being and the improvement of cognitive function.

You may stack it with different nutritional supplements or drugs to create a synergy that will give you the most desirable effect.

According to research, these are some of the best stacks to get the most out of the Pramiracetam nootropic.


When taking the supplement, you get the benefits and some side effects as well. One is the reduced choline in the brain. This should be on top of your stack list since it is vital to have enough choline supply.

Some of the best choline supplements are Alpha GPC and Citicoline. You can do any of these two drugs, and you will surely benefit from Pramiracetam without having to change your diet as well. It also helps decrease side effects such as headaches while on the nootropics.


Also known as an effective anti-anxiety agent. It also reduces stress, so you increase your focus and concentration for more productivity.

When stacked with Pramiracetam, your mental ability is stimulated, and your mood becomes better.

This combination of drugs reduces stress and anxiety so you can socialize and learn at the same time.

Other Nootropics

If you have not tried any nootropics before, you may try using Pramiracetam nootropic alone and feel its effects on your body. After several weeks, you may try stacking it with other nootropics relevant to the result you need.

Some of the nootropics to choose from are ArmodafinilModafinil, and Adrafinil. These smart drugs boost mental energy for more focus and concentration. People often stack it with any of these at times when they need long hours of studying.

Where to Buy Pramiracetam Capsules & Powder?

Pramiracetam can be bought in powder, capsule, or tablet forms. The FDA does not yet approve this drug in the US, but there is no regulation to buy it online.

buy pramiracetam powder

The best way to buy it is through a reputable site that has a proven track record of supplying legitimate nootropics like this website. One good thing about this site is that you can ask them for more details about the nootropics through their email address.

It has an independent testing laboratory and has been selling nootropics that have undergone strict scrutiny and research. It has different nootropics, and you can be assured it has Pramiracetam for sale on its website.

How Much Does it Cost?

Pramiracetam powder typically costs $1.50 to $2.00 per gram depending on the quantity ordered and other factors such as the quality of raw material used and the company selling it.

Pramiracetam capsules cost around $0.30 to $0.60 each, but that does not take into account shipping charges or individual state taxes that may be added onto each purchase which would drive up the price even further depending on location.

The best way to get a good idea of how much Pramiracetam will cost is to contact several suppliers and determine their price per gram.

Also, it is important to keep in mind that while the cost of Pramiracetam is relatively low compared to other racetams such as Aniracetam or Oxiracetam, the quality of the raw material used does matter when determining how effective it will be.

Phenylpiracetam vs. Pramiracetam: Which is Better?

If you're looking to improve your cognition or mood, then Phenylpiracetam may be a little better for you because of its stimulating properties. If you're looking to reduce the effects of Alzheimer's disease or PTSD, then Pramiracetam will be more effective. When making this decision, it is important to weigh the pros and cons of each nootropic.

Here's a list of the Pros and Cons of Phenylpiracetam:

Pros: Phenylpiracetam has some stimulating properties that would help with concentration. Not as expensive as Pramiracetam. It can reduce symptoms of Alzheimer's disease and PTSD.

phenylpiracetam vs pramiracetam

Cons: Can cause headaches if you take too much. Maybe more on the pricy side, depending on where you purchase it from (more expensive online).

Now let's look at some Pros and Cons of Pramiracetam:

Pros: Some studies show that Pramiracetam may promote the development of new neurons in adult brains, which may help you think more clearly and remember things better. Pramiracetam has been shown to reduce symptoms of Alzheimer's disease and PTSD. It is generally cheaper than Phenylpiracetam.

Cons: Not as much research is available about this nootropic compared to Phenylpiracetam. It can cause headaches if taken with poor form or too much, so be careful when purchasing it.

When weighing the pros and cons of each nootropic, it is crucial to consider your reasons for taking the drug in the first place.

If you are looking for productive results without hurting your wallet, Pramiracetam might be a better choice because it is usually less expensive than Phenylpiracetam.

phenylpiracetam vs pramiracetam

However, if you are looking for a drug with stimulating properties that you can also stay focused on, Phenylpiracetam is the better choice.

In conclusion, it's important to weigh the pros and cons of each nootropic when making your decision. When making this decision, you should consider your reasons for taking a nootropic drug in the first place.

Remember to be safe when taking these drugs and follow all directions your doctor or medical professional gives.

Frequently Asked Questions (FAQ)

If you have any questions that are bothering you, you may find the answers here.

How Long Does It Take to Work?

After ingesting the supplement, it usually takes 30-60 mins before you feel the effects happening. You become more alert, have more energy, and can easily absorb information.

Is It Safe?

The supplement is guaranteed low-risk, so it is safe to use according to the required dose.

Is It Legal?

Although the FDA does not yet approve it in the US, it is not restricted to buy Pramiracetam online. Russia and some countries in Europe use the drug to treat neurological diseases that cause memory loss.


Pramiracetam is a highly potent nootropic in the racetam family that promises better mental capabilities and prevents memory loss due to aging or neurodegenerative diseases or injuries.

Many people are using it to help them focus on their studies or to reduce the possibility of cognitive decline.

This product has undergone clinical trials on humans to test its effects. With all the distractions around, this nootropic is worth trying to improve your cognitive function and state of well-being.