Cerebrolysin Review: Benefits, Dosage, Side Effects & Where to Buy

Updated on January 13, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

People are often scared of getting old—more than having wrinkles all over the body, the fear of suffering from memory loss. But if you want to prevent that, or if you have a traumatic brain injury, then Cerebrolysin may be worth giving a try.

In this article, we are going to tell you more about the benefits of Cerebrolysin and the risks associated with it.

What is Cerebrolysin?

Cerebrolysin is a porcine brain-derived peptide preparation with a balanced composition of several neurotrophic factors that elicit pharmacological actions similar to that of the endogenous neurotrophic factors.

cerebrolysin information

Cerebrolysin thus mimics the action of several neurotrophins to enhance neuroprotection, neuroplasticity, and neuroregeneration and restores neuronal networks after injury.

These activities of Cerebrolysin are possibly achieved through regulating glycogen synthase kinase-3 and cyclin-dependent kinase 5 activity, besides enhancing synaptic density, neuronal plasticity, and regenerating neuronal cytoarchitecture.

Cerebrolysin is a low molecular neuropeptide drug improving the brain's ability for self-repair. It is made of peptides that stimulate the production of proteins and the removal of damaged neurons. It is produced from the enzymatic hydrolysis of a natural substance called Cerebrolysin. It is a complex fermentation process involving bacterial cultures and extracts of brain cells.

This substance is found in the brain of the common seal. The neuropeptides in Cerebrolysin can be used to repair the brain, improve cognitive abilities, and even promote neurorecovery after an injury.

Cerebrolysin can reduce beta-amyloid and tau protein levels in the blood. It has been proven that Cerebrolysin positively affects a control group suffering from mild to moderate dementia. It has been used in combination with other treatments to treat these patients.

There are a lot of other substances in Cerebrolysin, including omega-3 fatty acids, amino acids, vitamin B12, vitamin B6, biotin, inositol, phosphatidylserine, and a lot more.

How is Cerebrolysin Used?

Cerebrolysin is used to help people with brain injuries. This can be caused by an accident, a stroke, a brain tumor, or even a traumatic brain injury. The goal of using Cerebrolysin is to improve the patient's cognitive abilities.

In the case of Alzheimer's disease, Cerebrolysin can be used to reduce cognitive decline. It is used to stimulate the production of proteins and the removal of damaged neurons.

This substance can be used to treat dementia in general. It is also used for the following purposes:

  • To improve cognitive abilities
  • To reduce the cognitive decline
  • To reduce memory loss
  • To increase the number of brain cells
  • To improve the blood supply to the brain
  • To improve the brain's ability to regenerate itself

Cerebrolysin has also been used to improve the condition of the brain after a traumatic brain injury.

The substance is used to treat the following conditions:

  • Traumatic brain injury
  • Alzheimer's disease
  • Dementia
  • Memory loss
  • Dementia with Lewy bodies
  • Parkinson's disease
  • Frontotemporal dementia
  • Schizophrenia

How Does Cerebrolysin Work in the Brain?

Cerebrolysin helps reduce brain inflammation for better cognitive abilities by activating the production of proteins. It also helps in the removal of damaged neurons. This helps in reducing the damage caused by the beta-amyloid protein.

It also helps form new brain cells and remove brain cell damage.

cerebrolysin mechanism

The substance has a positive effect on the hippocampus and the cerebral cortex. It helps form new brain cells, improves cognitive abilities, and stimulates the production of new neurons.

Cerebrolysin is a neuroprotective substance. It helps in the removal of damaged brain cells. It helps in the formation of new brain cells. It also helps in the formation of new neurons and the repair of the brain.

Cerebrolysin helps reduce the levels of beta-amyloid and tau protein in the blood. It helps in the removal of damaged brain cells. It also helps in the formation of new brain cells.

Cerebrolysin helps improve the blood supply to the brain. It also helps in the removal of damaged brain cells.

Cerebrolysin Mechanism of Action

With the help of Cerebrolysin, the brain chemicals can work properly. The brain chemicals are the neurotransmitters and the neuropeptides.

Neurotransmitters are chemical messengers that are responsible for the transmission of signals from one neuron to another. They help in the transmission of information.

Neuropeptides are small proteins that are released in the brain. They are responsible for the communication between the brain cells.

The neurotransmitters and neuropeptides help in the formation of new brain cells and the removal of damaged brain cells.

Neurotransmitters and neuropeptides help communication between the neurons and the transmission of information.

Cerebrolysin is a neuroprotective substance. It helps in the removal of damaged brain cells. It also helps in the formation of new brain cells.

The proteolytic peptides derived from pigs' brains activate cell differentiation, boost nerve function and protect systems from damage.

Cerebrolysin is a medication that has been shown to improve learning in young, adult, and aged animals with various cognitive skills.

In models of cerebral ischemia, Cerebrolysin reduced the infarct volume, inhibited edema formation and stabilized microcirculation, increased survival rate, and normalized lesion-related learning deficits.

Positive results were also found using Alzheimer's disease models. In addition to its direct effects on neurons, Cerebrolysin appears to significantly increase the number of glucose transport molecules in the blood-brain barrier, which balances out critical energy deficits associated with this ailment.

The effects of acute drug treatment on enhanced brain activity have been studied in healthy subjects and patients with vascular dementia, as evidenced by increased peaks of alpha and beta frequencies between 8 and 13 Hz.

The reason brain cells don't function properly is unclear. Still, Cerebrolysin therapy can improve objective cognitive abilities and other health indicators in patients with diseases like vascular dementia or Alzheimer's type.

After only two weeks, patients saw improvements in how they felt on rating scales for symptoms such as quality of life, fatigue, and sense of well-being. The effects were independent of the type of dementia a patient had (e.g., senile dementia, Alzheimer's disease.) Mainly, patients report better well-being over the long term as they need less supervision and rely on themselves more.

The nerve-growth factor-like activity of Cerebrolysin or its neurotrophic activity, there is an evident significant reduction, and in some cases, stoppage of the progression of neurodegenerative process that normally occurs as we age.


There are endogenously-produced short biological peptides. The porcine brain-derived proteolytic peptide from Cerebrolysin is similar to this one. Although there's no direct measurement of pharmacokinetics, indirect data was established using Cerebrolysin's pharmacodynamic profile.

Cerebrolysin crosses the blood-brain barrier, and its neurotrophic activity can be detected in the blood plasma up to 24 hours after dosage.

The crossing in the blood-brain barrier was established as indirect evidence since preclinical studies and investigations have shown comparable pharmacodynamic actions on the central nervous system after intra-cerebroventricular application.

Benefits of Cerebrolysin

Cerebrolysin has numerous potential uses for the brain. It is a synthetic nootropic drug with low-molecular peptides and possesses neuroprotective and neurotrophic repair properties.

cerebrolysin benefits

Cerebrolysin has been proven to have neurotrophic action similar to nerve growth factors, which cause peripheral and central neuronal stimulation. The neuroprotective properties of this nootropic agent help to shield neurons from lactocidosis to prevent the formation of free radicals.

Cerebrolysin has been used for treating stroke, traumatic brain injury, dementia, and Alzheimer's disease.

Studies in vitro and in vivo have revealed multiple benefits of Cerebrolysin, including reduced excitotoxicity, inhibiting the formation of free radicals, the activation of the brain's microglial cells, neuroinflammation, and the activation of calpain and apoptosis.

Applying Cerebrolysin to your tissue culture cells can help them grow in size and the number of branches they have.

The promising effects of Cerebrolysin, along with improved clinical and functional outcomes for patients with ischemic strokes and neurodegenerative disorders, suggest its application in traumatic brain injury.

Cerebrolysin Experiences & Reviews Shared on Reddit

During the previous decade, several studies, primarily experimental, tried to learn about the effects of Cerebrolysin on different grades.

Let us take a look at users' experiences as shared on Reddit.

According to DoctorNootNoot:

"Cere increases one's metabolism by a great deal. I eat more than I normally do and have still managed to lose approx. 8kg of body weight in the past 9 months, while maybe adding 1kg of muscle."

According to Anonymous:

"I can safely say that Cerebrolysin is by far the best nootropic I have ever used. This is only three weeks in, but my memory, recall ability, sensitivity to music, observance over my emotions, thinking faculties have all improved to a noticeable amount."

Where to Buy Cerebrolysin Nootropic?

Cerebrolysin is a drug that can reduce the effects of metal nanoparticles on the brain. High doses are needed to protect the nerve cell damage in the cortex.

Cerebrolysin is most effective in countering brain pathology caused by Al neurotoxicity followed by Cu and Ag intoxication in identical doses.

If you want to experience the same benefits, you can buy Cerebrolysin from a reputable online drug store. Or better yet, buy from Cosmic Nootropic's website, so you are assured of quality nootropics that have undergone several tests to prove their authenticity and effects.

Cerebrolysin Dosage

If you want to prevent any further damage to your brain, you should take Cerebrolysin every day for at least 2 months. The dosage should be between 100 and 200 mg. This does enough to protect your brain from any damage.

However, if it is your first time taking the supplement, start with 50 mg and work your way up to the recommended maximum dosage with your doctor's clearance.

Healthcare providers often advise patients with dementia, organic brain disorders, and metabolic disorders to take 5-30ml every day for 10-20 days as required.

Children may also be administered with Cerebrolysin using 1 -2ml only.

Patients with postapoplectic complications and craniocerebral trauma should take 10-50ml daily.

Administration and How to Take Cerebrolysin?

The dose required to be high (5 ml/kg, i.v.) before 30 min heat exposure is necessary for Cerebrolysin to protect the nerve cell damage in the cortex.

Cerebrolysin can be delivered to the brain through nano-drug delivery or injection.

It is essential to consider how Cerebrolysin will be best delivered to the brain when taking it therapeutically.

Cerebrolysin Side Effects

The effects of Cerebrolysin are not the same for everyone. Some may experience side effects like headaches, drowsiness, diarrhea, and dizziness.

Some people experience allergic reactions when taking Cerebrolysin. In extreme cases, like when taken beyond the recommended dosage and for longer periods, side effects like kidney problems and heart failure may occur.

Cerebrolysin is not recommended for children under 18 years old.

Frequently Asked Questions (FAQ)

Your questions answered.

How Quickly Does Cerebrolysin Peptide Work?

You can feel the benefits after about two weeks of taking the supplement.

How Long Can You Take Cerebrolysin for Brain Health?

It is recommended to take it for 7 to 30 days then have a treatment-free period of 2 to 3 months. Do the same cycle, and don't forget to consult your doctor.

Does the FDA approve Cerebrolysin for the treatment of stroke?

It is not approved by the FDA in the United States, unlike in some European and Asian countries where it is even used to treat dementia, stroke, and traumatic brain injury.

Cerebrolysin Review: Conclusion

To conclude, Cerebrolysin is the best nootropic supplement to protect your brain from any damage.

Since it is a safe and effective nootropic, it is often used to treat several conditions and diseases that involve the brain.

The reviews and research findings suggest that Cerebrolysin is a good nootropic supplement to improve memory, enhance learning, reduce the effects of fatigue, and boost brainpower.