Cyclazodone: Benefits, Where to Buy & Dosage

Focus, sociability, and elevated mood are the common issues of people who need stimulants.

If you feel tired most of the day, even without doing extra physical activities, then read on because this topic on Cyclazodone might be for you.

Cyclazodone is a centrally acting stimulant that displays a more therapeutic effect than other compounds.

Although there are no human studies yet, this research product is a promising nootropic and stimulant with lesser toxicity than what’s currently available for consumption in the market.

Let’s find out more about Cyclazodone.

What Is Cyclazodone?

Cyclazodone has the chemical name of 2-(cyclopropylamino)-5-phenyl-1,3-oxazole-4-one. The American Cyanamid Company developed it in the 1960s as a centrally-acting stimulant.

what is cyclazodone

Its Simplified Molecular Input Line Entry System (SMILES) is C1CC1NC2=NC(=O)C(O2)C3=CC=CC=C3 and has a molecular weight of 216.09 g/mol.

Earlier studies have found that it is safer to use than Cyclopropyl Pemoline and other derivatives.

Pemoline is a stimulant drug used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy. However, it was prohibited for sale in some countries because of its adverse effects. For one, children who receive the medication suffered liver failures, which eventually led to death.

Cyclazodone is also compared to thozalinone, which is a stimulant used as an antidepressant in Europe. This substance was also banned because of its cardiovascular side effects.

Compared to these two, the margin of safety and therapeutic index of Cyclazodone (2-(cyclopropylamino)-5-phenyl-1,3-oxazole-4-one) is at a safer level. Still, as of writing, it is only available for research purposes in the US.

The patents stated that Cyclazodone could pass off as a psychotronic, energy booster, and anorexigenic. It is available in tablets and powder form for easier administration.

The compound had started growing its following when users experienced its effect in reducing fatigue. Like pemoline, it also has excitants with unique properties, setting it apart from sympathomimetic amines but with less stimulatory activity and toxicity.

EffectsIncreases focus and empathy, significantly boosts mood and motivation
Potential Side EffectsHeadache, anxiety, depression, cognitive fatigue, increased heart rate
Half-Life5 - 7 hours
Common Dosage5 - 20 mg daily
Content1 g
Money Back Guarantee30 days
Rating⭐⭐⭐⭐⭐ 4.5/5
Best VendorClick Here ›

Cyclazodone is different from the parent pemoline by an N-cyclopropyl group and can be considered a 4-oxy derivative of aminorex, fluminorex, and other restricted analogues or phenethylamines and amphetamines.

By structure, it's particularly close to fenozolone (N-ethyl pemoline) and thozalinone (N,N-dimethyl pemoline).

Despite its potential as a stimulant, human prescription is not yet advised since there is no study on the possible effects for long-term use as a stimulant substitute.

The lack of pharmacological data makes the compound unavailable for recreation nor treatment. Further, speculations about its hepatotoxic properties were also noted to prevent its use other than clinical studies.

Since Cyclazodone (N-cyclopropyl pemoline) is still useful for depression, anxiety, fatigue, and anorexia, users must observe the utmost caution and harm reduction practices.

The compound is in the prohibited list of the World Anti-Doping Agency.

Benefits & Effects

Some reports suggest that Cyclazodone has nootropic properties because of its similarities to central nervous system stimulants like methylphenidate and amphetamine.

cyclazodone benefits effects

Its highly commended properties are the low to moderate affinity for serotonin release and less toxicity.

The benefits of its specific effects, as studied on animals, were also recorded for documentation.

  • Cyclazodone exhibits central nervous system stimulant and antidepressant efficacy and potency similar to dextro-amphetamine, which lasts for 180 minutes and with a total excitation of more than 6 hours.
  • Possesses anorexic efficacy and potency with lesser toxicity, unlike that of dextro-amphetamine.
  • Cyclazodone has cognitive and physical stimulation because of its amphetamine-like agonist properties, which increases the concentrations of dopamine, serotonin, and noradrenaline in the synaptic cleft.
  • Provides strong wakefulness and stimulation.
  • Significantly boosts mood and motivation.
  • Verbal fluency and sociability.
  • Increases focus and empathy.

Dosage & How to Use

cyclazodone featured image

For purposes of research, the following Cyclazodone dosage guide is plotted for safety and precaution:

  • Light: 5mg
  • Moderate: 5mg - 15mg
  • Strong: 25mg - 30mg

Generally, the ideal dosage is only between 5mg to 20mg and on an irregular basis as it quickly builds tolerance. This dosage is suitable for the research purposes of students and the treatment of patients with ADHD.

The compound can be purchased in powder or tablets containing 1 to 30 mg of the substance. The pill is more comfortable to take, but others use intranasal administration as, according to Cyclazodone users, it requires less time to kick in.

When taking the powder form of Cyclazodone, make sure that you have the scale to measure the right dosage to avoid unpleasant effects.

Cyclazodone (N-cyclopropyl pemoline) has beneficial effects that can’t remain unnoticed by the nootropics community. Despite its regulation, people can still buy this substance from the internet while sold under prescription in some countries.

Side Effects

Cyclazodone is an analogue of pemoline; therefore, it has a stimulating effect but has less toxicity than other stimulants. There are no enough human studies to back its positive effects except the direct experiences of the users.

Low dosages do not pose any adverse effects, but with high dosage or when the body is adjusting to the introduction of the substance, the following may be experienced:

  • Increased heart rate
  • Frequent urination
  • Dry mouth
  • Teeth grinding (prolonged usage)
  • Increased body temperature
  • Compulsive redosing
  • Muscle cramps
  • Temporary erectile dysfunction
  • Drifting

There are also after-effects associated with Cyclazodone, which include:

  • Anxiety
  • Cognitive fatigue
  • Delusion
  • Depersonalization
  • Depression
  • Headaches
  • Irritability
  • Motivation suppression
  • Muscle cramps
  • Psychosis
  • Tactile hallucinations
  • Thought deceleration
  • Wakefulness

Experiences Shared on Reddit

Reddit users shared their experiences so that those who intend to try Cyclazodone will know how it can affect them.

According to Polaco157:

“As I figured it wud, the adrafinil significantly potentiated the effects. But the cyclazodone on its own was still very impressive. On an empty stomach, it kicks in ~30-40min. Lasts about 8hrs from the little I’ve seen. It provides strong wakefulness and stimulation.”

According to serduv:

“It's less euphoric than Adderall but extremely potent and functional. It absolutely does what you want it to do if you're trying to function at a decent level and/or prolong wakefulness. Very clean. It does elevate the mood just a bit as well - just not to where it's outside of normal…”

According to Nether-Animal:

“Took around ~35-45mg orally, first impressions are that this is a stronger substance than many are giving it credit for…What I didn't like were the cold, sweaty palms and lingering insomnia…Not much tweakiness to this, but noted an increase in heart rate, minor dry mouth, and I did get some sort of fringe-euphoria at these dosages. I am 30 and ~200lbs.”

Where to Buy Cyclazodone?

If you wish to try N-methyl cyclazodone, buy from reputable websites with third-party analysis, laboratory report, and with the highest chemical purity of products. has been serving its clients with transparency and integrity, ensuring that their products are of the best quality. It is a legit Cyclazodone vendor that offers secure ordering, money-back guarantee, and same-day shipping.

Frequently Asked Questions (FAQ)

Cyclazodone still has more to prove so if you are on the brink of checking this out but is clouded by some questions, let’s answer them here.

Is It Legal?

Cyclazodone can’t be directly considered as legal nor illegal. It is included in the World Anti-Doping Agency prohibited list as a banned stimulant but remains uncontrolled to some countries.

To countries like Germany and Switzerland, it is not controlled and is considered legal. It is mainly used as a medicine because of its pharmacological effect.

It is banned in the US when intended for human consumption because it is an analogue of pemoline, a banned substance.

What to Experience When Using This?

Users reported an elevated pulse rate a few minutes after ingesting but overall, they experienced a better mood, strong wakefulness and stimulation, and talkativeness. According to them, the effects of Cyclazodone were noticeable even after 8 hours from the last dose.

Upon using the compound, you will immediately experience the focus that you need. You will feel more energetic and alert, making you more productive with a sense of sharpness to details and information.


Cyclazodone might be the compound that could help treat central nervous system disorders, but without enough clinical trials on humans, its purpose of development will not be achieved.

With its comparative efficacy and more therapeutic properties, this could be the best option over amphetamines. It might also be used to treat obesity for its anorectic properties. While its margin of safety is also impressive, it might soon be available not only for research purposes but for medical purposes as well.

The nootropic community has also eyed its potential as a cognitive enhancer, drawing to the conclusion that Cyclazodone has even more cognitive benefits than most of the other related compounds.