Emoxypine Review: Benefits, Dosage, & Side Effects

Updated on January 3, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

In this Emoxypine review, we'll take an in-depth look at what this popular nootropic is. We'll also go over how Emoxypine works in the brain, information about the benefits, side effects, and where you can buy it online.

Emoxypine is used as a cognitive enhancer to improve focus and reduce anxiety. But generally, it is essentially a go-to supplement to enhance and stabilize mood.

If you are experiencing these problems, should you give it a try?

Emoxypine Review Summary

Emoxypine (also known as Mexidol) is an antioxidant with nootropic properties that is commonly used to treat anxiety, depression, and other mood disorders. Emoxypine also has neuroprotective effects and can help to improve cognitive function. It has been shown to be effective as an anticonvulsant which means it could help to protect the brain from seizure activity.

If you're looking for a supplement to help with cognitive function and mood, Emoxypine is definitely worth trying.


  • Has anxiolytic effects
  • Reduces stress
  • Anticonvulsant
  • Has neuroprotective qualities and anti-inflammatory action


  • The most common side effect is dry mouth

Overview of Emoxypine

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), commonly known as Mexidol or Mexifin, is a manufactured antioxidant produced in Russia when taken as the succinate salt by Pharmasoft Pharmaceuticals (a type of vitamin B6).

emoxyprine information

Emoxypine has been marketed as a potential treatment for anxiety, depression, and alcoholism. It is believed to work by increasing the availability of certain neurotransmitters in the brain. Research suggests that Emoxypine may also help protect the brain from oxidative damage, improve cognitive functioning, and increase energy levels.

The most common form of Emoxypine is a capsule containing 125 mg of succinate. It is believed that Emoxypine is most effective when taken twice a day, at least 30 minutes before meals. However, it is important to note that the recommended dosage of Emoxypine may vary depending on an individual’s age, gender, weight, and other factors. When taking Emoxypine, it is important to follow the instructions of a doctor or other healthcare professional.

In addition to its potential therapeutic properties, it is important to note that Emoxypine has a low potential for adverse drug effects. Studies have shown that it is well tolerated by healthy humans, with no significant side effects. However, it is recommended that women of childbearing age take a negative pregnancy test prior to taking Emoxypine, as individual intolerance to this drug has been reported.

How Does Emoxypine Work?

The mechanism of action of Emoxypine is not fully understood yet. It is believed to primarily act as an antioxidant and posses neuroprotective properties, as well as a mild calming effect. It is known to target the GABA-A receptors and possibly block acetylcholine receptors.

This is thought to provide some of the nootropic and anxiolytic effects of Emoxypine. Through its antioxidant capabilities, it may also protect the brain from oxidative damage caused by stress or alcohol. Additionally, it is thought to increase energy levels and reduce fatigue. These effects have been observed in several studies, although the exact mechanisms are yet to be determined.

Mechanism of Action

The antioxidant and membrane-protective actions of emoxypine are thought to be the mechanism of action, with the following main components:

  • Emoxypine inhibits the oxidation of biomembrane lipids by free radicals and reacts with peroxide radicals in lipids and hydroxyl radicals in peptides.
  • Enhances the activity of antioxidant enzymes, particularly superoxide dismutase, which generates and consumes lipid peroxides and active oxygen forms.
  • Increases the correlation prostacyclin/thromboxane A2 and prevents the generation of leukotrienes by inhibiting free radicals during the synthesis of prostaglandin catalyzed cyclooxygenase and lipoxygenase.
  • Increases the content of polar lipids (phosphatidyl serine and phosphatidyl inositol) and lowers the cholesterol/phospholipids ratio, indicating that it has lipid-regulatory properties; shifts structure transition into low-temperature zones, causing membrane viscosity to decrease and fluidity to increase, suggesting that it has lipid-regulatory properties; increases the lipid-protein ratio.
  • The membrane-bound enzymes affect phosphodiesterase, cyclic nucleotides, adenylate cyclase, aldoreductase, and acetylcholinesterase.
  • Increases the binding ability of the receptor complexes of the brain membranes, such as benzodiazepine, GABA, and acetylcholine receptors.
  • Stabilizes biomembranes, or the membrane structures of blood cells like erythrocytes and thrombocytes, after hemolysis or mechanical injury that causes free radical production.
  • Increases dopamine content and decreases monoamine levels in the brain.

Benefits of Emoxypine

As mentioned previously, Emoxypine is known for its nootropic effects. But it also offers several other benefits. Studies have shown that Emoxypine can reduce anxiety, improve cognitive function, and increase energy levels. It is also known for its neuroprotective and anti-inflammatory properties, which can help protect the brain from stress and oxidative damage.

emoxyprine benefits

Moreover, it has been shown to normalize the sleep-wake cycle and help with alcohol withdrawal, making it a potential therapeutic option for those struggling with addiction. While there are no healthy human placebo-controlled studies that meet our inclusion criteria, there have been no adverse effects reported from taking Emoxypine, and it is generally considered a safe and effective supplement.

Reduced Anxiety

Reduced Anxiety is one of the many benefits of Emoxypine. It purportedly works by normalizing the sleep-wake cycle and promoting enhanced cognitive function. Studies have demonstrated that Emoxypine has anxiolytic, anti-stress, anti-alcohol, anticonvulsant, nootropic, neuroprotective and anti-inflammatory action which can help to reduce anxiety.

In addition, reviews and testimonials from users of Emoxypine have reported that they have experienced a reduction in anxiety levels with no side effects. This has been a very welcome benefit to many users and has been praised by them.

Improved Memory

Improved Memory is one of the most notable benefits of Emoxypine. Studies have shown that taking the supplement can improve memory, which is great news for people looking to enhance their cognitive abilities. Emoxypine works by increasing the levels of acetylcholine, a neurotransmitter that is involved in memory formation and recall.

It also activates a number of other pathways that are involved in memory formation and recall, helping to improve overall cognitive function. In addition to increasing memory, Emoxypine has also been found to enhance mental clarity, focus, and overall mental performance.

Increased Energy Levels

One of the key benefits of taking emoxypine is its ability to provide increased energy levels. This is due to its ability to reduce fatigue and improve overall cognitive performance. Studies have shown that taking emoxypine can reduce fatigue, improve alertness, and improve focus.

This makes it particularly useful for people with busy schedules who need to stay energized and productive. Emoxypine can also improve physical performance by reducing lactic acid build-up, providing more energy for workouts, and increasing muscle recovery time.

Protection from Stress and Oxidative Damage

One of the key benefits of Emoxypine is its protective effects against stress and oxidative damage. Studies have shown that the compound can reduce markers of oxidative stress and help protect nerve cells from damage. It works by increasing the activity of antioxidant enzymes in the body, which help protect cells from damage caused by free radicals.

Also, Emoxypine has been found to reduce the production of stress hormones and help reduce inflammation. This makes it a potentially useful supplement for those who want to protect their bodies from the damaging effects of stress-related conditions.

Dosage and Administration of Emoxypine

Now that you know more about the benefits of emoxypine, you may be wondering what the optimal dosage is and how to take the supplement. Generally, the recommended dose of emoxypine is 125 mg to 250 mg per day, divided into two or three doses. It is generally taken with food or after meals. Women of childbearing age should take a pregnancy test before starting the drug.

It is important to note that emoxypine has not been studied in healthy human placebo-controlled trials, so the optimal dosage is largely unknown. Additionally, there have been no reports of significant side effects from taking emoxypine, but individual intolerance of the drug or other ingredients in the supplement should be taken into account. It is also recommended to start with a low dose and gradually increase it until the desired effects are achieved.

Common Side Effects of Emoxypine

When taken as directed, Emoxypine is generally well-tolerated and rarely causes any serious side effects. However, some common side effects have been reported with its use. These include headaches, dizziness, fatigue, nausea, and gastrointestinal discomfort.

It is also important to note that the use of Emoxypine may increase the risk of birth defects or other pregnancy-related complications in women of childbearing age. As such, it is recommended that women of childbearing age have a negative pregnancy test before using Emoxypine.

People who are allergic to Emoxypine or any of its components should also avoid taking it. Additionally, people with existing medical conditions should consult with their doctor before using Emoxypine.

Alternatives to Emoxypine

If you’re looking for alternatives to Emoxypine, Phenibut is one option. Phenibut is a nootropic that can be used for anxiety relief, improved cognition, and improved sleep. Studies have shown that it is effective in reducing anxiety and improving cognitive performance with low side effects.

However, it is important to note that Phenibut can be habit-forming, so it’s important to take the recommended doses and not exceed them. Additionally, it’s important to note that there is a risk of negative side effects if the recommended dosage is exceeded. Therefore, if you choose to use Phenibut as an alternative to Emoxypine, it’s important to consult your doctor first.

Reviews and Testimonials on Emoxypine

Now, let’s take a look at what people have to say about Emoxypine. Many users have reported that they have experienced benefits such as improved memory, increased energy levels, and reduced anxiety. One user even wrote that they experienced a welcome benefit of reduced stress and oxidative damage. Additionally, there have been no reports of any negative side effects from taking Emoxypine. This is likely due to its low potential for adverse drug reactions, as shown in studies.

Overall, the reviews and testimonials from users of Emoxypine are generally positive. This suggests that it is a safe and effective nootropic supplement that can provide several benefits. The next section of this review will discuss the proper dosage and administration of Emoxypine.

Where to Buy Emoxypine?

If you're looking for a reputable vendor of Emoxypine, Cosmic Nootropic is the best place to buy. Cosmic Nootropic offers high-quality Emoxypine capsules (Mexidol brand) in 125mg doses, which are both suitable for therapeutic purposes.

Their Emoxypine capsules are manufactured by Farmasoft and are free of contaminants. They also have a great customer service team that can answer any questions you may have about the product. So if you're looking for a reliable vendor of Emoxypine, Cosmic Nootropic is the best choice.

Conclusion: Is Emoxypine Worth Trying?

In conclusion, Emoxypine is a promising nootropic that offers a variety of benefits with minimal side effects. It has been reported to have anxiolytic, anti-stress, anti-alcohol, anticonvulsant, nootropic, neuroprotective and anti-inflammatory properties.

Studies have shown that Emoxypine can be effective in normalizing the sleep-wake cycle and promoting enhanced cognitive function. Furthermore, it is generally well-tolerated when taken at the recommended dosage.

As with any supplement, it is important to consult with a healthcare professional before starting a new regime. With these considerations in mind, Emoxypine may be worth trying for those seeking a safe and effective nootropic.