Emoxypine Review: Benefits, Dosage & Side Effects

In this Emoxypine review, we'll take an in-depth look at what this popular nootropic is. We'll also go over how Emoxypine works in the brain, information about the benefits, side effects, and where you can buy it online.

Emoxypine is used as a cognitive enhancer to improve focus and reduce anxiety. But generally, it is essentially a go-to supplement to enhance and stabilize mood.

If you are experiencing these problems, would you give it a try?

Read more about the product in this Emoxypine review.

Emoxypine Succinate Review Summary

In summary, Emoxypine (also known as Mexidol) is an antioxidant with nootropic properties that is commonly used to treat anxiety, depression, and other mood disorders. Emoxypine also has neuroprotective effects and can help to improve cognitive function. Emoxypine has been shown to be effective as an Anticonvulsant which means it could help to protect the brain from seizure activity.

If you're looking for a supplement to help with cognitive function and mood, Emoxypine is definitely worth trying.


  • Has anxiolytic effects
  • Reduces stress
  • Anticonvulsant
  • Has neuroprotective qualities and anti-inflammatory action


  • The most common side effect is dry mouth

What Is Emoxypine?

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), commonly known as Mexidol or Mexifin, is a manufactured antioxidant produced in Russia when taken as the succinate salt by Pharmasoft Pharmaceuticals (a type of vitamin B6).

emoxyprine information

Emoxypine has a molecular structure comparable to Pyridoxine (Vitamin B6). Its method of action is based on its antioxidant properties and membrane-protective properties. 

They did not seek clearance for any medical use in the United States or Europe because they are a Russian corporation; similarly, US and EU companies do not seek approval for any medical purpose in Russia.

How Does Emoxypine Work?

When utilizing Emoxypine, users can enjoy anti-stress, neuroprotective effects, anti-inflammation, and nootropic qualities. This is because of its ability to prevent free radical oxidation, boost antioxidant enzyme activity, modulate receptor complexes of brain membranes and the activity of membrane-bound enzymes, stabilize bio-membranes, and raise dopamine levels in the brain.

Mechanism of Action

The antioxidant and membrane-protective actions of emoxypine are thought to be the mechanism of action, with the following main components:

emoxyprine mechanism of action
  • Emoxypine inhibits the oxidation of biomembrane lipids by free radicals and reacts with peroxide radicals in lipids and hydroxyl radicals in peptides.
  • Enhances the activity of antioxidant enzymes, particularly superoxide dismutase, which generates and consumes lipid peroxides and active oxygen forms.
  • Increases the correlation prostacyclin/thromboxane A2 and prevents the generation of leukotrienes by inhibiting free radicals during the synthesis of prostaglandin catalyzed cyclooxygenase and lipoxygenase.
  • Increases the content of polar lipids (phosphatidyl serine and phosphatidyl inositol) and lowers the cholesterol/phospholipids ratio, indicating that it has lipid-regulatory properties; shifts structure transition into low-temperature zones, causing membrane viscosity to decrease and fluidity to increase, suggesting that it has lipid-regulatory properties; increases the lipid-protein ratio.
  • The membrane-bound enzymes affect phosphodiesterase, cyclic nucleotides, adenylate cyclase, aldoreductase, and acetylcholinesterase.
  • Increases the binding ability of the receptor complexes of the brain membranes, such as benzodiazepine, GABA, and acetylcholine receptors.
  • Stabilizes biomembranes, or the membrane structures of blood cells like erythrocytes and thrombocytes, after hemolysis or mechanical injury that causes free radical production.
  • Increases dopamine content and decreases monoamine levels in the brain.

Benefits of Emoxypine

Emoxypine is used in a variety of medical procedures in Russia. It is said to have anxiolytic, stress-relieving, anti-alcohol, anticonvulsant, nootropic, neuroprotective, and anti-inflammatory properties.

emoxyprine benefits

Emoxypine is thought to increase cerebral blood circulation, prevent thrombocyte aggregation, lower cholesterol levels, and have antiatherosclerotic and cardioprotective effects.

Good as a Nootropic

The main advantage of taking emoxypine is that it has nootropic properties. It works as a psychological aid, promoting increased concentration and cognition. It differs from other nootropics in that it protects neurons and increases blood flow to the brain. In contrast, other nootropics regulate or change the behavior of neurotransmitters such as serotonin in the brain. Emoxypine increases dopamine levels in the brain, which helps to boost cognitive abilities.

Cognitive Enhancer

Emoxypine has been found to improve mental performance. Studies have shown it to increase memory and focus while alleviating fatigue and boosting mood—people who have poor motivation but want to improve their cognitive function use this supplement.

Neuroprotection Ability

Emoxypine protects the brain's neurons from free radicals by acting as an antioxidant. Emoxypine reduces the damaging effects of free radicals on the brain's neurons by inhibiting free radical oxidation. This also contributes to its capacity to improve focus, learning, and memory.


Emoxypine, because of its anti-depressant qualities, helps reduce stress and anxiety. Emoxypine was shown to help people normalize and enhance their behavior after stressful circumstances by reducing anxiety. Furthermore, there were no documented adverse effects from taking emoxypine, which has become the standard when using traditional medications to treat mental illnesses.


The antioxidant characteristics of emoxypine allow it to provide additional support and protection for membranes. It boosts the activity of antioxidant enzymes like superoxide dismutase while decreasing free radical activity at the same time.


Emoxypine has been proven to boost immune system activation, particularly in macrophages. It is credited with acting as an anti-inflammatory, immunomodulatory, and immunostimulant.

Anti-inflammatory Drug

Emoxypine, because of its anti-inflammatory qualities, helps relieve pain and improves the repair of peripheral nerves. One study that looked into its anti-inflammatory properties discovered that it reduced back pain in those with lumbosacral radiculopathy.

Emoxypine Experiences and Reviews Shared on Reddit

Here are some of the experiences shared by the different users.

According to VZ_Twosix:

"Within less than an hour after dosing, my generalized anxiety symptoms (which can range anywhere from being mild to debilitating in nature) are virtually eliminated. Social anxiety, in particular, has become MUCH easier to overcome - the ability to harness self-confidence has seen a stark improvement, both in intimate and public settings."

According to Read_full:

"It's the most effective hangover remedy I tried so far. I hadn't much opportunity to test it (corona, and now I'm not drinking that much), but the few times I took it, I could drink ridiculously high amounts of alcohol and get away with it. It's hard to describe, but somehow I didn't feel the negative side effects of the alcohol that much, only the euphoria."

According to Hormesis:

"I really try and avoid posting completely subjective reports, but I'm going to break my own rule and say this: Emoxypine is a fantastic, seemingly underrated substance. The anxiolytic qualities are great, and the lack of impairment and complete absence of hangovers after an evening of alcoholic drinks is equally useful."

Where to Buy Emoxypine?

You can buy emoxypine from health stores or pharmacies, and online stores. It is available in capsules, tablets, liquids, and other forms. Pharmacies sell it as both prescription and non-prescription drugs.

First, find the right online store. You can check the price, reviews, and ratings on different websites. It is also a good idea to check whether the website you are about to buy from has a secure site. You can check the website of Cosmic Nootropic for Emoxypine and other supplements.

Emoxypine Dosage

Capsules are available in 500mg, 1g, 2g, and 5g. It is important to note that the dosage of emoxypine varies and should be taken based on the condition you are taking it for.

emoxyprine dosage

It is recommended to start with a low dose and gradually increase it. 

The dosage can be increased to the maximum recommended dose of 100mg per day. It is advised to take it once a day.

Emoxypine Succinate Dosage for Adults

The dosage for adults is as follows:

  • For adults taking it for a short period: 100mg/day
  • For adults taking it for an extended period: 200mg/day

Emoxypine is not known to interact with any other drugs. However, if you are taking any other medication, it is recommended to consult your doctor before taking it.

How to Take Emoxypine Powder and Pills?

Emoxypine should be taken in the morning on an empty stomach. It would be best if you did not take it with any other medication. It is important to remember only to take it at the recommended time.

The common pill available in pharmacies is 125 mg. The 125-250mg pill should be taken 1-2 times a day for 2-6 weeks. You should reduce the dosage within 2-3 days as you finish the treatment. The maximum dosage per day is 80- mg or 6 tablets.

Emoxypine Side Effects & Safety

Emoxypine is generally well tolerated. However, there are some side effects that you should be aware of.

emoxyprine side effects

Side effects of Emoxypine include:

  • Dizziness
  • Dry mouth
  • Headache
  • Insomnia
  • Nausea
  • Constipation
  • Diarrhea
  • Dry skin

The side effects are mild and generally, go away within a few days. However, if they are not going away within the time, you should consult your doctor.

Frequently Asked Questions (FAQ)

Your questions answered.

Is Emoxypine a Vitamin?

Emoxypine is a synthetic compound. It is very similar to vitamin B6. However, it is not intended to be used as a vitamin.

Will Emoxypine Get You High?

No, traditional neuropsychotropic medications have few side effects, which goes the same with Emoxypine. It has no sedatives, muscle relaxing, stimulating, or euphorizing actions, and no neuroprotective medication side effects.

What is the Half-Life of Emoxypine?

It has a quick onset and a short half-life of roughly 3 hours when taken orally. It may have a longer half-life in the body than some faster-acting nootropics because it is a slow-release medication.


Although Emoxypine is a promising compound with various benefits, its reviews are mixed. Some users report that it is an effective treatment for depression and anxiety. Others have found that it does not provide the relief they expected.

However, most users have found that it provides relief for the symptoms they are experiencing. The proper dosage can give therapeutic effects in many anxiety disorders and even cognitive impairments.

If you want to try Emoxyprine, read reviews and consult your doctor first.