Picamilon Review: Nootropic Benefits, Dosage, & Side Effects

Updated on December 10, 2022
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

In this Picamilon review, we'll take an in-depth look at this popular nootropic. We'll go over how Picamilon works in the brain, its benefits, side effects, and where to buy it online.

Have you heard of picamilon? It's a nootropic that's gaining popularity in the health and wellness community.

In this article, we'll discuss what picamilon is and how it can help improve your cognitive performance, reduce stress levels, and enhance your overall well-being.

Read on to learn more about this amazing supplement!

Pros

  • Has tranquilizing and psychostimulating effects
  • Has antiaggregant, and antioxidant effects
  • Acts as a vasodilator (dilates blood vessels in the brain)

Cons

  • Not FDA-approved
  • Limited research on safety and efficacy available

What Is Picamilon?

Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon)

is a drug that was developed in the Soviet Union in 1969 and further studied in both Russia and Japan. It is formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA). Once picamilon has entered the body, it is broken down into gamma-aminobutyric acid and niacin, which are thought to provide vasodilatory[1] and nootropic effects.

what is picamilon

The combination of these two chemicals has been found to help regulate stress-related hormones, as well as providing mental performance benefits. Picamilon is not considered a dietary ingredient, so it must be purchased from a licensed supplier.

The Basics of Picamilon: Chemical Structure and Function

Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA)[2]. It was developed in the Soviet Union in 1969 and further studied in both Russia and Japan. Once it has entered the body, it's broken down into GABA and niacin, which are both known to have a range of benefits.

Picamilon has been found to increase parietal cortical blood flow in rats and rabbits when administered at doses of 5-50mg/kg. This suggests that it could be effective for stress relief and mental performance enhancement.

The drug is also known to have vasodilatory and antihypertensive effects. This means that it can help to expand blood vessels and reduce blood pressure, which can be beneficial for those with cardiovascular issues.

It is important to note that picamilon does not meet the statutory definition of a dietary ingredient, so it cannot be sold as a dietary supplement in the United States. However, it is available for purchase from a variety of online retailers.

The History of Picamilon: Where Did it Come From?

Picamilon is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid. It was developed in the Soviet Union in 1969 and further studied in both Russia and Japan as a prodrug of GABA. Picamilon combines GABA and vitamin B3 to help regulate stress-related hormones, as well as providing vasodilatory and neuroprotective effects.

The development of Picamilon began in the Soviet Union in 1969 when scientists recognized the potential of combining GABA and niacin[3]. The combination of these two molecules was found to be more effective than either molecule alone, resulting in improved mental performance, stress relief, and an overall sense of well-being. In the decades since, Picamilon has been studied extensively in both Russia and Japan, where it has been used to help treat a variety of mental health conditions.

picamilon featured image

Today, Picamilon is widely available online in its pure form or as a part of various nutritional supplements. It is becoming increasingly popular among people looking to improve their mental performance, reduce stress, and increase their overall sense of wellbeing.

The Benefits of Picamilon

Picamilon is a powerful nootropic supplement with a range of benefits. It can help to improve mental performance, reduce stress, and promote relaxation. Picamilon is capable of increasing blood flow to the brain, which can lead to increased concentration and focus. It can also boost energy levels and mood, making it an ideal supplement for those looking to improve their cognitive functioning.

It has been used for decades in Russian and Japanese medicine for its ability to improve mental performance and its potential for treating anxiety and depression. While it has not been extensively studied in Western medicine, it is becoming increasingly popular in the nootropic world.

Picamilon for Stress Relief and Mental Performance

Picamilon is a powerful nootropic compound that has been used for decades to improve mental performance and reduce stress. It works by increasing blood flow to the brain, which helps increase oxygen and nutrient delivery to the brain. This helps to improve cognitive function and reduce feelings of stress. It also acts as an anxiolytic, helping to reduce feelings of anxiety and tension.

picamilon effects benefits

As a result, picamilon can help improve focus, concentration, and mental clarity, as well as reduce fatigue and enhance mood. Additionally, research has shown picamilon to be effective in treating conditions such as depression and insomnia. It can also help boost energy levels and enhance physical performance.

Where to Buy Picamilon

Picamilon is a powerful nootropic that can help improve mental performance and reduce stress. If you're looking for a reliable source for this supplement, then PureRawz is the way to go. PureRawz is a reputable online store with a wide selection of high-quality nootropic supplements, including picamilon. They offer pure and potent picamilon in powder form with a 98% purity percentage.

This means that you don't have to worry about any potential contamination from other ingredients. Plus, PureRawz offers competitive prices and fast shipping, so you can get the picamilon you need quickly and conveniently. Whether you're looking for improved mental performance or stress relief, picamilon is a great choice – and PureRawz is the perfect place to buy it.

How to Take Picamilon for Maximum Effectiveness

Taking picamilon is a simple process, as it does not require any special instructions or preparation. The recommended dosage for adults is between 50-100 milligrams per day, taken with meals or snacks. It is best to begin at the lower end of the dosage range and gradually work up if needed. You should also avoid taking picamilon in the afternoon or evening, as it may interfere with sleep.

When taken as directed, picamilon can provide a variety of cognitive benefits, including improved focus, better memory recall, and enhanced mental clarity. It can also help to reduce feelings of stress and anxiety, as well as improve mood and emotional regulation. To get the most out of your picamilon supplementation, it is important to combine it with healthy lifestyle habits such as eating a balanced diet, getting regular exercise, and getting enough sleep.

Picamilon Dosage: How Much to Take

Picamilon is a powerful nootropic drug, but it is important to be aware of the correct dosage for maximum effectiveness. When taking picamilon, it is recommended to start with a small dosage (50-100 mg) and increase gradually over time.

Generally, the recommended dosage for most adults is between 100-200 mg per day. It is important to note that higher doses of picamilon may cause side effects such as headaches and dizziness, so it is best to start with a lower dose and gradually increase over time.

Additionally, picamilon should not be taken in combination with other nootropics or medications without consulting with a healthcare professional first.

Picamilon's Side Effects: What to Watch Out For

Picamilon is generally considered to be a safe supplement, with few side effects reported. However, it is important to be aware of the potential side effects of taking Picamilon. Some of the most common side effects include headache, nausea, dizziness, and drowsiness. If any of these symptoms occur, it is important to reduce your dosage or discontinue use altogether.

It is also important to note that Picamilon can interact with certain other medications and supplements. If you are taking any prescription medications or other supplements, it is important to consult with your doctor before taking Picamilon. This will help you ensure that you are taking the right dosage and that your medications and supplements will not interfere with one another.

Interactions with Other Medications and Supplements

Picamilon is not known to interact with any other medications or supplements, however it is still important to be aware of any potential interactions. It is always best to consult with your doctor before taking any new supplement, including picamilon. Additionally, it is important to keep in mind that picamilon is a synthetic drug and should not be taken in place of prescribed medications.

It is also important to take picamilon in moderation and not to exceed the recommended dosage. Taking too much can lead to adverse reactions, such as headaches and nausea. Additionally, it is important to keep in mind that picamilon may increase the effects of other medications, especially those taken for anxiety or depression. It is important to talk to your doctor if you are taking any other medications or supplements to ensure there are no interactions.

Picamilon vs. Other Nootropics: A Comparison

Picamilon is a unique nootropic with a unique combination of benefits. It is a combination of niacin and gamma-aminobutyric acid (GABA), and it has been studied in both Russia and Japan as a prodrug of GABA. It is thought to improve stress-related hormones, provide vasodilatory effects, and increase parietal cortical blood flow in rats and rabbits when administered at certain doses.

When compared to other nootropics, Picamilon stands out due to its dual action of enhancing GABA activity while providing a neuroprotective effect on the brain. Other nootropics typically focus on increasing the activity of one neurotransmitter or system, such as acetylcholine or dopamine. Picamilon, however, works on two different systems at once, providing an enhanced effect. Additionally, due to its vasodilatory properties, Picamilon can increase blood flow to the brain, potentially leading to improved cognitive performance.

Finally, Picamilon is easy to find and relatively affordable compared to some other nootropics. It can be purchased from reputable online retailers such as PureRawz and is also sold in capsule form for convenience. With its unique combination of benefits, Picamilon is an excellent choice for those looking for a versatile nootropic that can deliver multiple cognitive benefits.

Conclusion: How Can Picamilon Improve Your Mental Performance?

Picamilon is a great nootropic for those looking to improve their stress levels and mental performance. Its combination of gamma-aminobutyric acid and vitamin B3 helps to regulate hormones, increase circulation, and improve focus and clarity.

It also has very few side effects and is safe when taken at the recommended dosage. If you’re looking for a natural way to enhance your mental performance, picamilon may be the perfect supplement for you. Just make sure to buy it from a reputable source and take it in accordance with the instructions provided.

References

References
1Mirzoyan R.S., Gan’shina T.S., Kosoi M.Y., Aleksandrin V.V., Aleksandrov P.N. “Effect of picamilon on the cerebral cortical blood supply and microcirculation in the pial arteriolar system” Bulletin of Experimental Biology and Medicine May 1989, Volume 107, Issue 5, pp 668-670
2Kuriyama K., Sze P.Y. “Blood-brain barrier to H3-γ-aminobutyric acid in normal and amino oxyacetic acid-treated animals”Neuropharmacology Volume 10, Issue 1, January 1971, Pages 103–108
3Kuchmerovs'ka, T M et al. “Korektsiia nikotynamidom ta nikotynoïl-HAMK obminu dofaminu v holovnomu mozku shchuriv za eksperymental'noho parkinsonizmu” [Correction by nicotinamide and nicotinoyl-GABA of dopamine metabolism in rat brain in experimental Parkinson's disease]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) vol. 73,6 (2001): 108-12.
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