Alpha Brain Review 2024: Our Honest Take on Effects & Value

Updated on March 4, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
Examination of Alpha Brain's cognitive enhancement effects, highlighted through a yellow, grey, and white color scheme

Welcome to our journey into the world of cognitive enhancement and health supplements with our unbiased review of Alpha Brain.

Does it truly sharpen the mind and elevate mental performance as it claims?

We’ve taken the plunge and experimented with this potent nootropic ourselves, now we’re ready to share our findings.

Stay tuned as we unravel the mystery.

Alpha Brain Review

Our thorough review of Alpha Brain reveals mixed sentiments.

We found its effects subtle at best when using Alpha Brain ourselves. Despite some positive anecdotes online, the consensus leans towards minimal impact.

We also note that while certain ingredients may theoretically support cognitive health, their actual efficacy within this blend is questionable due to low dosages or lack of synergistic effects among them.

Many users report no significant or lasting change in cognitive function.

This aligns with our experience, where the boost in mental clarity was there, but not prominent.

Pros of Alpha Brain

Let’s consider the benefits reported by some users:

  • Enhances focus and concentration
  • Assists mental clarity
  • Non-GMO and gluten-free formula

These pros suggest there could be individual variations in response to the Alpha Brain formula.

Cons of Alpha Brain

However, drawbacks are evident:

  • Inconsistent results across users
  • Lackluster increase in alpha brain wave production
  • High cost without guaranteed outcomes

Such cons cast doubt on its value as a cognitive enhancer for many people seeking clear benefits from supplements like these.

About Alpha Brain

what is alphabrain

Onnit Labs is the company behind Alpha Brain, a name that has become synonymous with brain health. They’ve carved a niche for themselves in the wellness market by focusing on cognitive enhancement.

Their product stands out due to its proprietary blends of ingredients aimed at improving various brain functions.

Alpha Brain’s reach extends far beyond just niche markets; it has garnered widespread popularity. This is partly due to endorsements from public figures, like Joe Rogan, and athletes who advocate for the brain-boosting benefits of this supplement.

One clinical study on Alpha BRAIN has provided preliminary evidence suggesting that it may support executive function by production of alpha brain waves.(1)

It’s not just about memory; Alpha Brain claims to assist with focus, mental clarity, and even dream vividness.

Customer Reviews & Feedback

The customer review landscape for Alpha Brain presents a dichotomy of experiences. While many users praise the nootropic for enhancing focus, mental clarity, and memory recall, others are disappointed due to unmet expectations and mild side effects.

Overall, satisfaction levels are varied, with a portion of users experiencing noticeable cognitive benefits and others finding the product lacking or problematic.

This suggests that Alpha Brain’s effectiveness may be individual-specific, and it is not universally effective for all consumers.

Positive Reviews of Alpha Brain

Many users report satisfaction with Alpha Brain. They say it meets their expectations for cognitive enhancement.

The product seems to support better focus and mental clarity. Some of us noticed improved memory recall after regular use. The effects are subtle, but significant enough to be appreciated.

  • Enhanced focus
  • Increased mental clarity
  • Improved memory recall

Negative Reviews of Alpha Brain

Not all experiences echo this sentiment. A fair share of customers feel let down by Alpha Brain.

Some expected dramatic improvements that didn’t materialize. Others experienced mild side effects that marred their overall experience with the product.

  • Unmet high expectations
  • Mild side effects like headaches or jitteriness

It’s clear from the critical reviews that Alpha Brain isn’t a one-size-fits-all solution.

Our Experience with Alpha Brain

onnit alpha brain reviewed

When the package from Onnit arrived at our WholisticResearch office, we were eager to see if Alpha Brain could live up to its claims. The delivery was swift, arriving sooner than we anticipated. The packaging itself was sleek and professional, hinting at the premium nature of the product within.

Over a period of three weeks, Jason Williams, George Collins, and Yoko Hill put Alpha Brain to the test.

Jason noticed an improvement in his concentration levels during long meetings. “It’s subtle, but I feel more present,” he said after two weeks of consistent use. However, he also mentioned that some days it didn’t seem to make much difference.

George found that while his brain fog seemed reduced on most days, there were moments when he questioned if it was merely a placebo effect or genuine clarity from the supplement. “Some mornings felt clearer,” George reflected, “but then there are afternoons where I can’t tell if it’s working.”

Yoko offered a mixed review as well; she experienced bouts of enhanced focus but also reported no significant change in her overall cognitive function over time. Her impression leaned towards mild skepticism: “I wanted it to be a game-changer,” she admitted with candidness.

Throughout our trial period, we observed that the individual experiences varied between mild improvements and negligible changes.

Effectiveness & Results

Performance CategoryRating
Cognitive Enhancement⭐⭐⭐☆☆ 3.0/5
Focus and Concentration⭐⭐⭐⭐☆ 4.0/5
Memory Improvement⭐⭐⭐☆☆ 3.0/5
Learning Enhancement⭐⭐⭐☆☆ 3.0/5
Mood Stabilization/Enhancement⭐⭐⭐⭐☆ 4.0/5
Energy Boost⭐⭐⭐☆☆ 3.0/5
Brain Health Improvement⭐⭐⭐⭐☆ 4.0/5
Neuroprotection⭐⭐⭐☆☆ 3.0/5
Neuroplasticity Improvement⭐⭐⭐☆☆ 3.0/5
Cognitive Clarity and Focus⭐⭐⭐⭐☆ 4.0/5
Creativity Enhancement⭐⭐⭐☆☆ 3.0/5
Stress Reduction⭐⭐⭐⭐☆ 4.0/5
Reaction Time Improvement⭐⭐⭐☆☆ 3.0/5
Anxiety Reduction⭐⭐⭐⭐☆ 4.0/5

Our journey with Alpha Brain took us through varied experiences. We closely followed the outcomes reported by our team members: Jason Williams, George Collins, and Yoko Hill. Each brought a unique perspective to the table.

Jason noted an increase in productivity within the first few weeks of use. He felt his cognitive performance was sharper during work hours. However, he didn’t notice significant changes in his long-term memory recall abilities.

George’s feedback was more on the neutral side; he observed slight improvements in his executive functioning but questioned whether these changes were due to Alpha Brain or the placebo effect from his expectations.

Yoko experienced a different set of effects. Her ability to maintain focus improved marginally but came with mild side effects like headache and jitteriness initially.

These symptoms subsided after a few days, suggesting some degree of adaptation over time.

We noticed differences between short-term and long-term effects among our group members:

  • Short-term observations included enhanced focus and mental clarity.
  • Long-term effects were less consistent across our group, with some reporting sustained improvement in the brain’s cognitive processing speed while others did not see lasting changes.

The lack of uniformity in responses suggests that factors such as individual brain chemistry and lifestyle might influence outcomes when using nootropics like Alpha Brain.

Despite mixed reviews on its efficacy, we found that there is potential for improvement in certain areas of cognitive function for some users.

Alpha Brain Ingredients & Supplement Facts

Alpha Brain’s meticulous selection of ingredients is designed to target various aspects of mental health, from memory and concentration to stress resistance and neurotransmitter support. Here’s a closer look at the key ingredients and their respective quantities contained within the product:

  • Vitamin B6 — 10 mg
  • Cat’s Claw Extract — 350 mg
  • Onnit Flow Blend — 650 mg
    • L-Theanine
    • L-Tyrosine
    • Oat Straw Extract
    • Phosphatidylserine
  • Onnit Focus Blend — 240 mg
    • Alpha-GPC
    • Bacopa Monnieri
    • Toothed Clubmoss Extract
  • Onnit Fuel Blend — 60 mg
    • L-Leucine
    • Pterostilbene
alpha brain ingredients

Vitamin B6 — 10 mg

Vitamin B6, also known as pyridoxine, is an essential nutrient that plays a pivotal role in maintaining healthy brain function and overall well-being. It aids in the production of neurotransmitters, which are crucial for brain communication and can help regulate mood and cognitive abilities.

Research has shown that B6 reduces the risk of age-related cognitive decline, and a particular study found that higher B6 levels are associated with better verbal memory and executive function performance.(2)

The daily recommended intake for adults ranges from 1.3 to 2.0 mg, and 10 mg of Vitamin B6 can support cognitive health without the risk of toxicity.

Cat’s Claw Extract — 350 mg

Cat’s Claw extract, derived from the Uncaria tomentosa vine, is celebrated for its immune-boosting and anti-inflammatory properties. Packed with antioxidants, it’s thought to aid in cognitive function by reducing brain inflammation and oxidative stress.

Research indicates that Cat’s Claw enhances DNA repair, which is crucial for maintaining neuronal integrity and function. One study showed a 53% increase in DNA repair in cells treated with Cat’s Claw extract.(3)

We believe that a 350 mg dose could be beneficial, as it aligns with dosages used in some clinical trials.


L-Theanine is an amino acid found in tea leaves, known for its calming effects on the brain. It promotes relaxation without drowsiness, making it beneficial for improving focus and cognitive function.

A study found that L-Theanine improved attention and reaction times in individuals with anxiety.(4) Moreover, L-Theanine has been shown to synergize with caffeine to enhance cognitive performance, particularly in attention-switching tasks and alertness.

If L-Theanine is dosed correctly (typically ranging between 100 – 200 mg) within the Onnit Flow blend, it could offer a significant cognitive boost without overstimulation.


L-Tyrosine is an amino acid that plays a pivotal role in the production of neurotransmitters such as dopamine and norepinephrine. These chemicals are crucial for cognitive processes, including memory, attention, and problem-solving.

Health benefits of L-Tyrosine include stress reduction, improved mental performance under pressure, and potential alleviation of mood disorders.

Research suggests that L-Tyrosine is particularly beneficial for cognitive function during stressful situations or when one is fatigued. A study found that tyrosine supplementation improved cognitive flexibility, the brain’s ability to switch between thinking about one concept to another, in participants.(5)

Considering the total Onnit Flow Blend dosage of 650 mg, it’s unlikely that L-Tyrosine amount aligns with the recommended dosage of 500 mg – 2000 mg for cognitive benefits.

Oat Straw Extract

Oat Straw Extract is derived from the green stems and leaves of the Avena sativa plant, traditionally used for its medicinal properties. It’s rich in antioxidants, which contribute to overall health and wellness. Specifically, its health benefits include reducing inflammation, improving mood, and supporting heart health.

For cognitive function, Oat Straw Extract is known to enhance blood flow to the brain, which can improve concentration and focus.

Research indicates that it also increases alpha-2 waves in the brain, associated with enhanced alertness and reduced anxiety.


Phosphatidylserine is a phospholipid, which covers and protects the cells in your brain and carries messages between them. It plays a critical role in ensuring your mind’s proper function and has been linked to enhanced memory, mood, and cognitive capacity.

Research suggests that phosphatidylserine can help combat age-related cognitive decline. For instance, a study showed a significant improvement in the cognitive performance of elderly patients with Alzheimer’s after taking phosphatidylserine supplements.(6)

Given that effective doses of phosphatidylserine are typically between 100 – 300 mg, its impact could be diminished if it’s not adequately dosed within the blend.


Alpha-Glycerylphosphorylcholine (Alpha-GPC) is a cholinergic compound that helps improve brain function. It increases levels of acetylcholine, a neurotransmitter pivotal for memory and learning.

Research supports its potential in enhancing cognitive ability, with studies indicating improvements in attention and memory recall among participants. One clinical study on Alpha GPC found that its supplementation improved cognitive function in Alzheimer’s patients within 3 to 6 months.(7)

We believe that the Alpha-GPC dosage within the Onnit Focus Blend might be lower than the clinically studied amounts, which could limit its cognitive enhancement benefits. Considering the total blend is only 240 mg, it’s uncertain if this provides an effective dose of Alpha-GPC.

Bacopa Monnieri

Bacopa Monnieri, commonly known as Brahmi, is a traditional Ayurvedic herb recognized for its potential to enhance cognitive function and mental speed.

Research indicates that Bacopa supports memory, learning, and concentration, due to its active compounds called bacosides, which protect the brain against oxidative stress and improve neurotransmission.

One study found that participants taking Bacopa extract showed significant improvement in memory retention compared to the placebo group.(8)

We believe that the efficacy of Bacopa Monnieri in the Onnit Focus Blend may be compromised due to the limited dosage; 240 mg for the entire blend suggests that Bacopa, as one of several ingredients, is unlikely to be present at an optimal level.

Toothed Clubmoss Extract

Toothed Clubmoss extract, containing the cognitive-enhancing compound Huperzine A, improves memory and protects nerve cells. It acts as a cholinesterase inhibitor, increasing levels of neurotransmitters associated with learning and memory.

A medical review in the Journal of the International Society of Sports Nutrition suggests that Huperzine A helps with cognitive impairments.(9) It has been shown to improve memory function in students significantly.

We believe that while Toothed Clubmoss extract has promising benefits, its efficacy in a blend hinges on proper dosing. Given that the total Onnit Focus Blend is 240 mg, without specific dosage information for the extract, we remain cautious.


L-Leucine is an essential amino acid, crucial for protein synthesis and muscle repair. It’s a key component of branched-chain amino acids (BCAAs), which are vital for health and athletic performance. Health benefits of L-Leucine include enhanced muscle growth, improved endurance, and better regulation of blood sugar levels.

Clinical studies suggest that L-Leucine also influences neurotransmitter synthesis and helps maintain the balance of nitrogen in the body, which is essential for neural health.(10)

Clinical trials have shown that BCAAs help improve cognitive function in individuals with liver disease, indicating a potential broader benefit for brain health.

Given that Onnit Fuel Blend is only 60 mg, L-Leucine must be lower than the clinically effective dosage typically recommended for its physical benefits.


Pterostilbene is a powerful antioxidant found in blueberries and similar to resveratrol, known for its potential benefits, including support for heart health and glucose metabolism.

It has gained attention for its neuroprotective properties. Research suggests that pterostilbene enhances brain health by reducing oxidative stress and inflammation, key factors in cognitive decline.(11) One study found that pterostilbene improved memory and prevented age-related cognitive deterioration in rats.

Regarding cognitive benefits, pterostilbene promotes the preservation and function of brain cells, thus supporting memory, learning, and overall cognitive performance.

We believe that the efficacy of pterostilbene in the Onnit Fuel Blend may be compromised due to the low dosage, as 60 mg is split among two ingredients. Considering the research on effective dosages, it’s possible that the amount of pterostilbene included is not sufficient to yield the cognitive benefits suggested.

Alpha Brain Side Effects & Safety

While many people use this nootropic without any issues, we’ve come across experiences from individuals that shed light on possible adverse effects.

Jason reported feeling slight headaches after starting Alpha Brain. George experienced some jitteriness, which may be attributed to the natural stimulants in the formula. As for Yoko, she noticed difficulty sleeping, which might be a reaction to the L-theanine content designed to boost alpha waves but sometimes can affect sleep patterns.

We’ve compiled a list of potential side effects based on user reports:

  • Headaches
  • Jitteriness or nervousness
  • Difficulty sleeping
  • Nausea or stomach discomfort
  • Dizziness

These symptoms are generally mild and often subside as your body adjusts to the supplement. However, it’s important for each of us to monitor how our bodies react.

When approaching a new supplement, adhere to its guidelines. Onnit recommends taking 2 capsules of Alpha BRAIN with a light meal.

Price & Value for Money

Alpha Brain’s price tag is steep. A single bottle of 30 capsules (which lasts only 15 days) sets you back by $34.95, a notable sum compared to other supplements on the market.

But many of us are willing to invest in our mental performance if the product delivers results. Some have noticed improvements in their daily tasks that justify this expenditure, yet others remain skeptical.

The cost may be justified for those who do benefit significantly from Alpha Brain if they opt for the subscription plan, which comes with a 15% discount.

Where to Buy Alpha Brain

Alpha Brain is readily available through various online platforms. You can purchase it directly from the official Onnit website, which provides detailed information about the product and customer support. The official site offers domestic delivery within 3-5 business days, but international shipping times vary greatly.

Online marketplaces like Amazon also list Alpha Brain and some physical stores carry this supplement. Buying from reputable sources ensures you receive an authentic product.

Alpha Brain Alternatives and Similar Supplements

Some may find Alpha Brain too costly or want different benefits. Others might experience side effects they wish to avoid. The best supplements to consider include Feedamind, Mind Lab Pro, and Vyvamind, which offer unique advantages.

Alpha Brain vs Feedamind

Feedamind is a nootropic supplement that supports optimal acetylcholine levels, just like Alpha Brain does. However, it is somewhat more affordable with similar cognitive enhancements.

We tried it and noticed an improvement in our focus without the jitters some of us felt with Alpha Brain.

Our brief review of Feedamind highlights its pros:

  • More comprehensive 16-ingredient formula
  • Effective at enhancing mental clarity
  • Fewer reported side effects

Choosing this over Alpha Brain makes sense for us because we get comparable results while saving money—something we all appreciate.

Alpha Brain vs Vyvamind

Vyvamind is another contender in the nootropic space, vying for the attention of those seeking a mental edge. Just like its counterparts, it’s designed to boost cognitive function, but it stands out with its unique formulation.

Our team tested Vyvamind, and we were quite impressed by the sustained concentration, mood balance, and energy levels it provided, all without the common crash associated with stimulants.

Here’s a snapshot of what we found appealing about Vyvamind:

  • Contains a blend of potent nootropic ingredients
  • Delivers a smooth energy boost without the harsh side effects
  • Supports long-term brain function and brain energy

Even though Vyvamind is more expensive than Alpha Brain, this brain supplement clearly provides superior nootropic effects.


Review CriteriaRating
Cognitive Efficacy⭐⭐⭐☆☆ 3.0/5
Ingredient Quality & Safety⭐⭐⭐⭐☆ 4.0/5
Side Effect Risk⭐⭐⭐⭐☆ 4.0/5
Research & Evidence⭐⭐⭐☆☆ 3.0/5
Cost-Effectiveness⭐⭐⭐☆☆ 3.0/5
Personal Experience⭐⭐⭐☆☆ 3.0/5
User Feedback⭐⭐⭐⭐☆ 4.0/5
Overall Rating⭐⭐⭐☆☆ 3.7/5

After diving deep into the world of Alpha Brain, we’ve laid out all the facts for you. From our hands-on experience to dissecting each ingredient, we’ve covered every base. The consensus? It’s a mixed bag, but there’s potential for those seeking a cognitive boost.

Sure, some of us felt sharper, while others didn’t notice much. Side effects were minimal, thankfully. And while the price tag isn’t peanuts, if you’re chasing that edge in mental clarity, it might just be your ticket.

Just remember to keep those expectations in check and consult with your doctor —safety first, folks!

And hey, if Alpha Brain isn’t your jam, no sweat—there are plenty of fish in the nootropic sea.


Is Alpha Brain really worth it?

Wheying its pros and cons, Onnit’s Alpha Brain may be valuable for some, offering nootropic effects and cognitive support, but its effectiveness can vary by individual. Many people love Alpha Brain and some are not impressed at all.

Is Alpha Brain safe for everyone?

Alpha Brain is generally considered safe for healthy adults, but it’s important for individuals with pre-existing medical conditions, pregnant or nursing women, or those taking other medications to consult a healthcare provider before using it. Studies on Alpha Brain’s formula reveal that its natural ingredients offer a mental boost without serious side effects. This cognitive support supplement is also non-GMO, caffeine-free, and gluten-free.

How long does Alpha Brain last?

Generally, Alpha Brain’s effects last for more than 6 hours. According to an analysis of some consumers, the cognitive effects may last more than 8 hours.

How quickly can one expect to see results from Alpha Brain?

The time it takes to notice the effects of Alpha Brain can vary among individuals. Some users report experiencing improvements in focus and mental clarity within a few hours to a few days of taking the supplement, while for others, it might take longer to observe noticeable changes.

How does Alpha Brain work to enhance cognitive function?

Alpha Brain works by combining various nootropics and natural ingredients that are believed to target cognitive processes. These ingredients may help enhance neurotransmitter production, improve blood flow to the brain, and support overall brain health, potentially leading to improved memory, focus, and mental clarity.

Can Alpha Brain improve long-term brain health?

While Alpha Brain is designed to support cognitive function in the short term, there is limited research on its long-term effects on brain health. Some ingredients in Alpha Brain may contribute to overall brain health, but consistent, long-term benefits are yet to be conclusively established through scientific studies.

Sources, Studies, and Scientific Research
  1. Solomon, Todd M., et al. “A randomized, double-blind, placebo controlled, parallel group, efficacy study of alpha BRAIN® administered orally.” Journal of the International Society of Sports Nutrition 12.sup1 (2015): P54. ↩
  2. Balk, Ethan M., et al. “Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials.” Archives of internal medicine 167.1 (2007): 21-30. ↩
  3. Snow, Alan D., et al. “The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.” Scientific reports 9.1 (2019): 561. ↩
  4. Hidese, Shinsuke, et al. “Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial.” Nutrients 11.10 (2019): 2362. ↩
  5. Jongkees, Bryant J., et al. “Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands—A review.” Journal of psychiatric research 70 (2015): 50-57. ↩
  6. Kim, Hee-Yong, Bill X. Huang, and Arthur A. Spector. “Phosphatidylserine in the brain: metabolism and function.” Progress in lipid research 56 (2014): 1-18. ↩
  7. Sagaro, Getu Gamo, Enea Traini, and Francesco Amenta. “Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.” Journal of Alzheimer’s Disease Preprint (2023): 1-12. ↩
  8. Kongkeaw, Chuenjid, et al. “Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.” Journal of ethnopharmacology 151.1 (2014): 528-535. ↩
  9. Mei, Zhengrong, et al. “Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.” Metabolic Brain Disease 32 (2017): 1861-1869. ↩
  10. Wang, Xiaotian, et al. “Leucine mediates cognitive dysfunction in early life stress-induced mental disorders by activating autophagy.” Frontiers in Cellular Neuroscience 16 (2023): 1060712. ↩
  11. Poulose, Shibu M., et al. “Effects of pterostilbene and resveratrol on brain and behavior.” Neurochemistry International 89 (2015): 227-233. ↩