The 7 Best Vitamins for the Brain for Adults

Updated on February 10, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
The impact of vitamins on adult brain health and cognitive function.

Brain supplements are popular and used by 25% of adults over the age of 50. However, the FDA has not required manufacturers to prove their effectiveness or make disease-specific claims. This means that the benefits of brain supplements are uncertain.

However, there are certain factors you can consider to ensure that you’re getting the most out of your brain vitamins.

How to Choose the Best Vitamins for the Brain for Adults?

Selecting the right brain vitamins for adults involves considering several critical factors to ensure efficacy and safety. Each aspect plays a pivotal role in the overall impact these supplements can have on cognitive health.

FactorDescriptionWhy It’s Important
Ingredient QualityThe purity and source of the vitamins and whether they are synthetic or natural.High-quality ingredients ensure better absorption and effectiveness, reducing the risk of contaminants or fillers.
Scientific EvidenceClinical research and studies supporting the effectiveness of the vitamins for cognitive benefits.Supplements with proven scientific backing offer more assurance that they will deliver the promised benefits.
Dosage & PotencyThe amount of each vitamin in a dose and its concentration.Adequate dosages are necessary to achieve therapeutic effects without risking overconsumption and side effects.
BioavailabilityThe body’s ability to absorb and utilize the vitamins.Higher bioavailability means more nutrients reach the brain, leading to improved cognitive functions.
Synergistic CombinationHow different vitamins work together to enhance overall brain health.Certain vitamins may work better in combination, offering a comprehensive approach to cognitive support.
  • Ingredient Quality: The foundation of any effective supplement is the quality of its components. High-grade ingredients are more likely to be absorbed efficiently and provide the intended brain health benefits.
  • Scientific Evidence: It’s essential to choose supplements backed by clinical trials and research. These studies validate the claims made by the supplement brand and assure you that the product can support cognitive function.
  • Dosage & Potency: The correct dosage ensures that you are receiving enough of the vitamin to make a difference without risking toxicity or side effects. Potency also matters, as more potent formulations can offer greater benefits.
  • Bioavailability: This reflects how much of the vitamin your body can actually use. Superior bioavailability translates to more of the vitamin reaching the brain, where it can exert its effects.
  • Synergistic Combination: Some vitamins have complementary actions and can provide more significant benefits when taken together. For instance, vitamin B12 and omega-3 fatty acids work in tandem to support brain health.

The Best Vitamins for the Brain for Adults of 2024

According to our in-depth research and testing, the best vitamins for the adult brain are:

1. Mind Lab Pro

Mind Lab Pro is a nootropic supplement that improves the cognitive function and health of the brain. It contains natural ingredients that can heal damaged brain cells and eliminate brain fog. It can be taken two times daily. It is best for adults, over 18 years of age.

It also contains ingredients that improve mood. People who take Mind Lab Pro feel better about themselves and are more able to focus. It contains ingredients like dopamine, which promotes a positive attitude. It also activates serotonin and epinephrine. This promotes mental clarity, which is vital when you’re under pressure.

Unlike amphetamine-like drugs, Mind Lab Pro is gentle on the body. It helps replenish healthy neurotransmitters and supplies the brain with proper nutrition. The effects of Mind Lab Pro can last up to three hours. However, it is recommended to take it for at least 30 days. While it is not FDA-approved, it is considered safe and undergoes extensive quality control.

2. NooCube

The NooCube formula contains the active ingredients that have been specifically chosen for their ability to enhance cognitive function in adults. One of these ingredients is L-alpha-glycerylphosphorylcholine, or Alpha-GPC, which is being studied for its potential as a treatment for Alzheimer’s Disease. It is a substance found naturally in foods like eggs and broccoli, and its regular supplementation can help improve memory and brain processing.

NooCube contains antioxidants and other substances that help to repair damage in the brain. It also helps to grow new brain cells. This is crucial because the brain is constantly forming new connections. These connections are what help us solve problems and create memories. In addition, NooCube helps to increase the production of acetylcholine, a neurotransmitter that plays a role in improving cognitive performance.

NooCube is a legal nootropic that uses clinically studied ingredients that support healthy cognition. Its ingredients have been carefully selected by top neuroscientists who discovered the most effective cognitive enhancers and the correct doses to maximize their benefits.

3. Vitamin B12

Vitamin B12 is a nutrient that supports the mitochondria in the brain. Some studies have shown that it can protect the brain from diseases, such as Parkinson’s disease. It has been found to reduce homocysteine levels and protect neurons against oxidative stress. Taking vitamin B12 with omega-3 fatty acids can also help protect neurons from this type of damage.

One study shows that about one in eight older adults are not getting enough B vitamins. This deficiency can have profound effects on the brain. Low B12 levels are associated with cognitive problems, dementia, and other mental impairments. Many people are not aware that vitamin B12 deficiency can lead to these conditions.

While vitamin B12 and omega-3 fatty acids have been shown to reduce the risk of developing brain diseases, the mechanisms by which these nutrients work are not entirely understood. More research needs to be done on these nutrients.

4. Vitamin B6

Vitamin B6 is an essential nutrient for the brain, helping to maintain brain health as we age. It promotes the growth of new neurons and helps transmit information to different areas of the brain. A deficiency of this nutrient is associated with cognitive decline. In addition, it helps regulate homocysteine levels, which are linked to cognitive decline.

Although all B vitamins have beneficial effects on the brain, B-6 is particularly important for regulating mood and preventing mental fatigue. As a water-soluble vitamin, B-6 helps the brain produce serotonin, a neurotransmitter that lifts the mood. It also helps the body create hemoglobin, which carries energy-boosting oxygen to the brain. It is also thought to improve memory.

Moreover, vitamin B6 is found in a variety of foods, including chickpeas, beef, chicken, fish, and bananas. Some multivitamins and B-vitamin complexes also contain B6. It is usually present in P-5-P form, which is considered to be more bioavailable. Most B-vitamin supplements contain this form in ranges from 30 to 250 mg.

5. Vitamin B3

Vitamin B3 is an essential nutrient that plays an important role in brain health and memory retention. Deficient levels can lead to memory loss and confusion, and a study in 2004 found that those who consumed vitamin B3 daily had a lower risk of cognitive decline. This vitamin is found naturally in meat and dairy products and is often fortified in many grains.

As we get older, our bodies tend to use less vitamin B3, a sign that we may be missing out on important nutrients. However, new research suggests that increasing vitamin B3 intake may decrease the risk of Alzheimer’s disease and other types of dementia. Also, a higher amount of this vitamin has been linked to a reduced rate of cognitive decline in older adults.

Vitamin B3 is also known as niacin, and it plays an important role in numerous bodily functions. It helps to break down food, aids in digestion, and improves the nervous system. It is also involved in cell signaling, and helps repair DNA. Niacin converts to NADH, which in turn creates energy in the form of adenosine triphosphate (ATP). Niacin also helps reduce blood pressure, reduces anxiety, and improves memory.

6. Omega-3 Fish Oil

For long-term health benefits of Omega-3 Fish Oil vitamins for the brain, the fatty acids in these supplements must get into the brain. Sadly, there is no known cure for Alzheimer’s disease, which is a debilitating disease of the brain that causes severe memory loss. The disease is a growing public health concern with an estimated 5.7 million people in the United States.

While the benefits of fish oil are well-documented, there are some side effects. For example, high doses of omega-3 dietary supplements can lower the immune system and increase the risk of stroke and bleeding. This means that the best way to take fish oil for brain health is to work with a healthcare provider, who can diagnose your specific condition and recommend an appropriate dosage.

Studies have shown that omega-3 supplements can improve memory. They have also been shown to improve children with ADHD, autism, and cerebral palsy. Moreover, studies have shown that these supplements can improve the memory capacity of young adults by 25 percent. According to the researchers, this is equivalent to a drop of three years in age. With the number of cases of dementia rising at a rate of one million per year, these supplements may be helpful for preventing memory loss.


DMAE is a type of omega-3 fatty acid that is naturally produced by the human brain. However, it has not yet been studied in depth in humans. Because of this, it is not known if it can improve the health of adults. Some researchers are studying the effects of DMAE to improve the function of the brain.

DMAE helps the brain produce acetylcholine, a chemical messenger that is essential for learning and memory. Supplementation with this vitamin has been linked to significant improvements in short-term memory. However, it should not be taken by pregnant or nursing women. In addition, people with epilepsy, bipolar disorder, or other disorders should not take this supplement.

While there are a few caveats with DMAE, it is generally safe for adults. DMAE can interact with other drugs and herbal supplements. Certain types of antipsychotics and cholinergic drugs may increase the effects of DMAE. Some herbs with acetylcholinesterase properties may also interact with DMAE.

What to Consider Before Buying Vitamins for the Brain for Adults?

Before purchasing brain vitamins, it’s crucial to weigh several factors that can influence their safety and effectiveness. These considerations will help you make an informed decision aligned with your health goals.

1. Personal Health Status

Understanding your current health status, including any deficiencies or pre-existing conditions, is crucial when selecting a brain supplement. Certain vitamins may be more necessary for you than others based on your individual health profile.

2. Potential Interactions

Consider any medications or supplements you’re currently taking, as some vitamins may interact with these substances. For example, vitamin E has blood-thinning properties and could interact with anticoagulant medications.

3. Lifestyle and Diet

Your dietary habits and lifestyle choices can influence your need for supplementation. For instance, if you consume a balanced diet rich in omega-3s and B vitamins, you may not need as much supplementation as someone with dietary restrictions or poor nutritional intake.

4. Budget and Value

Evaluate the cost of the supplement in relation to its quality and the duration of supply. Expensive does not always mean better, but investing in a reputable brand with transparent ingredient sourcing can be worthwhile.

5. Third-party Testing

Look for brain vitamins that have undergone third-party testing for quality assurance. This testing can verify the purity of the vitamins and ensure they are free from harmful contaminants, providing an additional layer of trust and safety.