Looking for a nootropic that might help with ADHD and make you livelier?
Fasoracetam may help with these matters (and more) with little to no side-effects.
Our Fasoracetam review reveals if this is true or not.
What Is Fasoracetam?
Fasoracetam [R] is a non-stimulant and part of the Racetam family of nootropics. Created initially as a vascular dementia treatment, it wasn't until recently that researchers began considering it as a potential ADHD treatment [R].
In 2013, NeuroFix, a U.S-based firm, bought all the clinical research from its creator, Nippon Shinyaku, a Japanese pharmaceutical company.
In 2015, the U.S. Food and Drug Administration (FDA)'s Investigational New Drug program permitted its use in human clinical trials. For now, most of the human studies in the U.S. involving the use of Fasoracetam aren’t publicly accessible. But the few released studies show a strong indication that the nootropic may be a potent treatment for specific forms of ADHD.
There have also been animal studies that indicate the drug might improve sleep, boost memory, minimize withdrawal symptoms, and alleviate anxiety and depression [R]. Anecdotal evidence from people who have tried the compound also supports these claims.
Currently, Fasoracetam is still not FDA-approved and bears the classification of a research chemical that’s not for human use. Nonetheless, more and more people are experimenting with the drug. They cite the many positive findings regarding its effect on the human body.
Effects & Benefits
Fasoracetam works by influencing the following functions:
Fasoracetam increases the hippocampus and brain cortex’s choline uptake, which in turn increases acetylcholine levels. Acetylcholine is a neurotransmitter that influences your general cognition and learning ability. The higher your acetylcholine levels, the higher your overall mental performance will be.
Glutamate is a crucial neurotransmitter that aids the functioning of the brain. Low glutamate levels can lead to ADHD, depression, epilepsy, and other mental and physical disorders. Fasoracetam triggers glutamate receptors and modulates how metabotropic glutamate interacts with different receptors in your brain, which in turn prevents the disorders mentioned above by modulating metabotropic glutamate receptor activity.
GABA is another essential inhibitory neurotransmitter that affects mental performance and learning abilities. It also minimizes anxiety and aids healthy sleep. This compound can increase the release of GABA, creating a calming effect in the brain and central nervous system.
Using Fasoracetam can benefit your body in the following ways:
Alleviate Withdrawal Symptoms
Withdrawal during recovery from substance abuse can be physically and mentally painful. The good news is that several Fasoracetam users claim using the drug minimizes withdrawal symptoms when recovering from misuse of Phenibut, gabapentin, and other GABA-related CNS depressants.
But understand that no documented research exists to prove this claim or the safety of the drug for this purpose.
Treat Depression and Anxiety by Improving Mood
Since low GABA receptor activity in the brain can lead to depression symptoms, increasing GABA receptor function is an effective treatment. Fasoracetam increases the activity of GABA receptors in the human brain, making it ideal as a mood enhancer and antidepressant.
Unlike drugs that treat depression through other means, its effect is longer lasting. That’s because GABA receptors remain active once they are triggered, meaning you won’t need continuous doses of the drug to maintain healthy GABA receptor activity.
Also, aside from treating depression, Fasoracetam may alleviate anxiety disorders and aid sleep by increasing the brain’s GABA production, which calms the central nervous system.
Boost Memory, Cognition, Focus, and Concentration
The effects of Fasoracetam on mental performance and cognitive function are what’s primarily driving its popularity among users. How does the drug boost mental performance?
Choline and acetylcholine are brain chemicals that contribute to retentive memory and mental alertness. It can trigger the brain’s production of choline, leading to users feeling sharper and more focused.
Its effect, in this regard, is similar to using stimulants, but without the side-effect of feeling wired and restless. Also, improved concentration from higher levels of choline lets users focus on tasks, learn faster, and better utilize their intelligence.
Aside from being useful as a study aid that improves memory recall, older people who are experiencing cognitive decline can also benefit from using Fasoracetam. With proper doses, such people will experience improved speech, judgment, and mental clarity.
Potential ADHD Treatment
Clinical trials indicate that the drug could potentially treat Attention Deficit Hyperactivity Disorder (ADHD) which is partially caused by interrupted mGluR neurotransmitter signaling. A clinical trial that occurred in 2016 focused on children between the ages of 12 and 17 that had a specific glutamate receptor system mutation.
After taking Fasoracetam for over five weeks, ADHD symptoms in the children with this specific mGluR mutation of network genes reduced, and the positive effects remained long after the study. Plus, unlike other ADHD drugs, the children didn’t develop a tolerance or dependence. That means the drug could replace amphetamine derivatives, like Adderall, as an effective non-stimulant alternative for ADHD treatment for ADHD patients with sufficient efficacy.
While animal testing verifies many of the above benefits, publicly available research on its effect on humans, especially for those on anxiety and depression medication, is still lacking.
Like other nootropics from the Racetam family, using Fasoracetam powder in proper doses is crucial to getting the desired effects.
That said, because studies about the drug’s effects on humans are still ongoing, definitive guidelines regarding the perfect dosage don’t exist yet. During the earlier mentioned ADHD trials, children received single oral doses of 50-800 mg. Afterward, 400 mg twice daily doses were given for four weeks based on the symptoms of the patients.
In another study, 14 Japanese men received 100 mg doses daily.
Because it is highly potent, many users indicate that using just 20 mg once or twice daily is enough to get the desired effects. To be on the safe side, we recommend starting at the lowest effective dosage and gradually working your way up as necessary.
Since the putative nootropic drug is water-soluble, you can use it with or without eating. Many users prefer using it sublingually because it works faster that way. But that might not be feasible for you due to the drug’s extreme bitterness.
More importantly, available evidence from ADHD trials shows that users building a tolerance or dependence on the drug is unlikely, even at higher doses. Nonetheless, to be safe, use the drug cyclically rather than continuously.
Based on the experience of users and the few available clinical trials, Fasoracetam seems safe for human use, especially when used in reasonable doses. The risk of developing tolerance or dependence is also minimal.
That said, same as with other nootropics, some users may experience mild and transitory symptoms, such as:
- Digestive discomfort
- Reduced libido
Since Fasoracetam increases your brain's choline output, these symptoms likely occur due to exhaustion of your brain's choline reserves. Fortunately, you can reduce these symptoms by combining it with a choline supplement.
If you keep experiencing such side-effects after using a choline supplement, it’s possible your body just isn’t compatible with it. Also, since there’s a shortage of information regarding specific interactions between Fasoracetam and other drugs, avoid use of this novel cognition enhancer if you are on any prescription medication or have pre-existing medical problems.
People with impaired kidney function should also avoid using the drug or consult a doctor before using it. The same goes for pregnant or nursing women.
Here are what some Redditors have to say about their experience using this particular Racetam nootropic:
According to undrwatersquad:
“…I just started taking it a few days ago. I tried 20 mg by mixing it with water in a shot glass, then drinking it. I didn't notice anything the two times I tried that. This morning, I took 30 mg sublingually, and certainly noticed a difference. I felt calm, even though I have things coming up to stress about (school exams). Had a super productive day, no problems with staying focused…”
According to sswagpresident1337:
“Been taking it since the start of the year. First as a means to not develop a tolerance to phenibut bit soon I noticed it benefits on its own. Its like being on a low dose phenibut constantly. I often times had this "man if this doesnt work out im f****d" anxiety which is completely gone since using it…”
According to mc2a:
“I have been taking Fasoracetam for the last 2 weeks (almost every day) and having the same incredible anti-anxiety effects. Dose ~15mg sublingual. It's the only thing that helped, and I've tried benzos, phenibut, ashwaganda, l-theanine, bacopa, aniracetam. Haven't noticed any tolerance and hoping it won't be an issue with this substance…”
To get the best effects, many users enhance its effects by stacking it.
Some of the more potent Racetam nootropics stacks include:
Fasoracetam + Noopept + Choline
If you want to improve your focus and mental acuity, this is the perfect stack. Fasoracetam and Noopept will increase your mental performance while adding choline to the mix, thus replenishing choline reserves and reenergizing you.
For best results, take a morning dose of 500 mg of Alpha GPC Choline and 10 mg of Fasoracetam and Noopept. Round up your day with an evening dose of 10 mg Noopept.
Fasoracetam + Coluracetam
Here’s a stack for those who want brighter moods and more energy. Fasoracetam boosts GABA-B production while Coluracetam improves mood. The stack can also sharpen your focus and help with neurological disorders.
The recommended dose is two doses of 10 mg of Fasoracetam and Coluracetam per day.
Where to Buy Fasoracetam?
The quality of a drug goes a long way in determining its potency and safety. It’s even more so when the drug in question is unregulated.
For a batch of Fasoracetam that delivers desired results and nothing more, we recommend buying from a trustworthy and reputable source like Science.bio.
When in need of a nootropic that can boost your focus, memory, and mood without leaving you feeling wired or buzzed, Fasoracetam is the way to go.
When appropriately used, its side effects are negligible.
So it's a safe and cost-effective alternative to stimulants that delivers the same results more effectively than other Racetam compounds.