Noopept Sublingual: Best Route Of Administration?

Updated on March 19, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
Exploring the effectiveness of sublingual Noopept in enhancing neural connections.

Noopept is a nootropic supplement that has become increasingly popular in recent years. It has been shown to improve cognitive abilities, focus, and memory.

While it can be taken orally and intranasally, there is another route of administration that many people are turning to – sublingual.

But what exactly is sublingual administration? How does it compare to the oral application, and is it safe?

Let’s find out!

Taking Noopept Sublingually

Sublingual Noopept involves directly dissolving Noopept powder under the tongue instead of ingesting a pill orally. This route of administration is advantageous in that it avoids digestion and metabolization processes that can slow down or reduce the effects of the nootropic compound.

It is also extremely convenient to take Noopept since you do not need any water or other beverage, as it can be placed directly on the tongue.

According to our review of Noopept, sublingual absorption allows Noopept to go through the salivary glands, enter the bloodstream and cross the blood-brain barrier (BBB) faster than if taken orally. This means that it is more likely to have an increased effect on cognition, alertness, and overall mental performance sooner than if ingested orally.

Although this method may be slightly uncomfortable due to the taste and texture of the Powder form of Noopept, some people also report a quicker onset of effects when taking it sublingually or even snorting Noopept. With the oral method, Noopept can be less effective, as enzymes in our body take it apart before it reaches the bloodstream.

Both methods may cause headaches, anxiety, or some fatigue, but remember that the sublingual route, being more concentrated, has higher risks.

If you’re particularly sensitive to the nootropic, consider taking it orally to slow down the absorption rate or supplementing choline to counteract the side effects.

Dosage & How To Take Noopept Sublingually

Noopept, known for its high bioavailability and ability to rapidly cross the blood-brain barrier, should be taken in 10 – 30 mg/day doses. For optimal absorption rates, allow the tablet or powder to dissolve under your tongue for direct entry into your bloodstream and brain – bypassing digestion altogether.

If you’re brand new to taking Noopept sublingually, we recommend starting with a low dosage of 5 mg daily and increasing it at your discretion. Be sure to monitor how your body is responding and adjust accordingly.

Consult with your physician if you’re unsure about anything discussed above, especially since some of these nootropics aren’t regulated by the Food and Drug Administration (FDA). Also, you shouldn’t take Noopept before sleep.


Noopept is a very potent brain enhancer, and taking it sublingually can provide numerous benefits. Sublingual administration results in more rapid absorption into the bloodstream, allowing Noopept to reach its peak effect more quickly.

This method also bypasses digestion, meaning that more of the nootropic compound will be delivered directly to your brain for maximum cognitive enhancement. Thus, taking Noopept sublingually is an effective and convenient way to get the most out of this powerful nootropic substance.

Ready to experience what the Noopept powder has to offer? You can find it right here: