Noopept Sublingual: Best Route Of Administration?

Updated on October 8, 2022
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

Before you use Noopept to boost your brain health, you should know there are different types of administration.

You can opt to take Noopept sublingually, orally, or even intranasally.

The question is, which method is the safest and most effective?

Taking Noopept Sublingually

Sublingual Noopept involves dissolving Noopept powder under the tongue instead of swallowing a pill whole.

Now, what's the difference between the two?

Even though according to our review of Noopept, taking it orally allows it to cross the blood-brain barrier fairly quickly, the sublingual route digests into your bloodstream much faster.

Nootropics work more effectively when they bypass the processes of digestion and metabolization.

sublingual noopept

Sublingual Noopept allows the chemicals to go through the salivary glands, enter the bloodstream, and distribute throughout the whole body without being broken down.

This means that the effect of the nootropic is much more potent—you'll find that it's better at improving your memory, enhancing your cognitive functions, and stabilizing your mood.

With the oral method, Noopept can be less effective, as enzymes in our body take it apart before it reaches the bloodstream.

However, some users may find the taste quite unpleasant, which is why they prefer taking the pill or to even snort Noopept. If you find the powder difficult to get down, Noopept sublingual may not be the best option for you.

Now, both methods may cause headaches or some fatigue, but keep in mind that the sublingual route, being more concentrated, has higher risks.

If you're particularly sensitive to the nootropic, consider taking it orally to slow down the absorption rate or supplementing choline to counteract the side effects.

Dosage & How To Take

The recommended Noopept dosage is typically between 10 to 30 mg per day, depending on how much you weigh.

However, if you're taking it sublingually, you may want to start with 5 mg, just to see how your body reacts to it.

Measure the correct amount of powder, place it under your tongue, and leave it there for around 1-2 minutes. Once it has dissolved, you can rinse your mouth with water, juice, or mouthwash to remove the bitter taste.

Once you are more used to the effects of Noopept, you can gradually increase the dose.

However, make sure you consult your physician if you're unsure about anything, especially since some of these nootropics aren't regulated by the Food and Drug Administration (FDA). Also you shouldn't take Noopept before sleep.


Those wanting to experience the maximum benefits of Noopept may opt to take the sublingual route of administration over the oral one.

Ultimately, this method is quick, direct, and effective but also a lot more potent, so be cautious!