Armodafinil: Review of Nootropic Effects, Uses, & Side Effects

Updated on April 2, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

We look at what Armodafinil is and how it can treat excessive sleepiness, sleep disorders and keep the brain healthy. We then look at recommended dosage, side effects, and where you can buy Armodafinil online.

Armodafinil is a smart drug that works to treat excessive sleepiness, improve wakefulness and alertness and treat three major conditions. These conditions include shift work sleep disorder, obstructive sleep apnea, and narcolepsy. It also helps keep the brain healthy and can even improve cognitive function.

This article looks at the medication in closer detail as well as recommended dosage and side effects and how although in many places it can only be prescribed, buying armodafinil off of an online vendor can be a viable option. Keep reading to find out everything you need to know about Armodafinil.

What is Armodafinil?

Armodafinil Review

Armodafinil is a smart drug that is used to attract serious nootropic users. Armodafinil works to target three major medical conditions. These include narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

It is a wakefulness-promoting agent which was approved to treat these conditions whilst also promoting enough sleep to keep the brain healthy and treat daytime excessive sleepiness.

Although it can improve sleep quality and encourage good sleep habits, it does not work to cure these conditions entirely and will only work as long as you take it.

The medicine is not available to buy over the counter and is only available via a doctor's prescription in the dosage form of a tablet or available to buy online.

Armodafinil is one of the most popular nootropics to treat excessive sleepiness and promote wakefulness discussed on Reddit (we have included some user reviews below) and can also be used as a way of treating cognitive abilities and enhancing productivity.

It has been proven to enhance cognitive function as using Armodafinil can improve thinking skills, learning, motivation, and attention span. Therefore some like to use the smart drug to boost productivity and heighten concentration and focus. As it can treat extreme sleepiness and help you feel more awake, which can further improve concentration and focus.

It's also used off-label as a way of treating attention deficit hyperactivity disorder, depression, dementia, chronic fatigue syndrome, and a range of other health conditions.

Armodafinil is the 'R' enantiomer of Modafinil and this is a compound that consists of two molecules that are non-superimposable mirror images.

Armodafinil was manufactured by Cephalon which is a pharmaceutical company that produces Modafinil. However, it is marketed as a completely separate drug.

R-modafinil has a half-life of 10-14 hours, compares to 3-4 hours of S-Modafinil, and can be as much as three times greater than the circulating levels of Modafinil.

Armodafinil and modafinil are therefore placed side by side to treat sleep disorders but Armodafinil has been labeled as the better and stronger version of Modafinil.

Armodafinil Dosage

A regular dosing schedule of Armodafinil is vital to minimize side effects and use the drug safely.

You should take Armodafinil as directed by your doctor and only take as much as your doctor tells you to. You should also only take it for as long as they advise you to.

Only take it as your doctor tells you and what the medication guide on the label says. Never change this dosage without guidance.

If you suffer from obstructive sleep apnea or use a continuous positive airway pressure machine at night, you can continue to use this machine whilst taking Armodafinil.

Take Armodafinil at the same time each day and tell your doctor if you need to change your schedule.

The strength of armodafinil will also determine what dosage you should be taking. This is always determined by the number of doses, the medical problem or sleep disorder it is being used to treat and the length of time you take it.

When taken orally in the form of tablets to treat narcolepsy and obstructive sleep apnea adults should take 150 mg to 250 mg daily in the morning and children should rely on their doctor to advise them of dosage.

When taken orally to treat shift work sleep disorder, adults should not take a high dosage of 250 mg and instead take 150 mg one hour before the start of work. For children, the same applies as above.

Most generic Armodafinil medications come in 150 mg pills and this is why 150 mg is usually the recommended dosage. Although doses up to 250 mg are tolerated, there are usually no extra benefits.

Although a dosage of 300 mg has been tested, this has been found to be too strong and might be overwhelming for the majority of users. It might also lead to further side effects such as insomnia and irritability.

There are cases however when 300 mg might be suitable, but this dosage should only be taken by someone who is roughly over 200 pounds and over 6 feet tall. This way, you will be able to metabolize Armodafinil faster than the average person.

If you end up using 300 mg of armodafinil, do not take it more than two times a week and they should be taken at least 3 days apart to regulate your sleep-wake cycle.

On the other hand, doses as small as 75 mg have also been prescribed and this could be a suitable dosage for smart drug beginners or someone sensitive to stimulants. It might also be a good dosage for someone who wants to enhance their focus for a much shorter time or are unsure of how their body might react to a normal dose of Armodafinil.

Talk to your doctor or pharmacist before taking the medicine and never take more than advised.

What do I do for a missed dose? If you ever find you have missed a dose of this medicine, take it as soon as possible. However, if it's nearly time for your next dose, go back to your regular dosing schedule.

What are the Side Effects of Armodafinil?

As with all herbal products and medicines, there are possible side effects associated with using Armodafinil. It is always best to speak to a doctor or pharmacist before starting any new medication to find out how using Armodafinil can affect you and how you can benefit fully from its uses.

Tell your doctor and remind them of any pre-existing conditions he will have on your medical file, that could affect usage.

The most common side effects seen when taking Armodafinil include:

  • Nausea
  • Dry Mouth
  • Anxiety
  • Diarrhea
  • Dizziness
  • Headache

The side effects listed above are usually mild and only occur when you use Armodafinil incorrectly. They usually fade away as the body adjusts to the primary ingredients in the drug.

However, there are other side effects associated with taking Armodafinil and these include:

  • Suicidal Thoughts
  • Anxiety
  • Mental Illness Changes
  • Mood Changes
  • Chest Pain
  • Trouble Breathing
  • Blisters
  • Irregular Heartbeat
  • Depression
  • Mania
  • Rash
  • Frequent Urination
  • Fever
  • Trembling or shaking

These are adverse effects and rarely occur, yet when they do, it usually has to do with misuse or drug abuse. Seek immediate medical attention if you experience any of these other adverse side effects

Moreover, consult a healthcare professional or tell your doctor immediately if common side effects don't subside.

Armodafinil Interactions

Drug interactions occur when two or more drugs are taken at the same time. This can increase side effects and the effectiveness of combined medications. You should not use Armodafinil with:

  • Certain antifungus
  • Birth Control Pills
  • Anticoagulants
  • Monoamine Oxidase
  • Certain Antidepressants
  • Antepileptic Drugs such as diazepam

It is always best to tell your doctor about any medication you are on before adding Armodafinil. Though they have access to medical records, if they miss something, improper drug interaction could cause serious issues.

The nootropic should also be taken with caution when you have a health condition such as cardiovascular disease, a psychiatric or psychotic disorder, or liver dysfunction.


When it comes to storage, store the medicine in a closed container and keep it at room temperature. Keep it away from heat, moisture, and direct light, and don't let it freeze.

Ask your healthcare professional how to dispose of the medicine when it has gone out of date or you no longer need it.

Armodafinil Experiences Shared on Reddit

Here are some reviews of Armodafinil from users and contributors on Reddit.

According to 'cold-flame':

'Armodafinil makes me active, makes me able to talk properly, makes me wanna socialize, and so on. The focus on Armodafinil is still all over the place, but the typical symptoms of SCT are relieved to some extent.

I have probed enough with my body and mind to eliminate other issues, like sleep apnea, malnutrition, etc. But no matter what, the lack of energy and brain fog is always there. But Ritalin and Armodafinil help very much.'

According to 'maddymix94':

'Armodafinil did work for me, no need to sleep during the day, my sleep schedule got better and no more problems at night. BUT I get more cataplexy now than before.'

According to 'Flangella-Fairyfloss':

'The first time I had modafinil 200mg I started to crash after a few hours. The next day I tried 150mg armodafinil and it lasted me all day.'

Where to Buy Armodafinil

When it comes to buying armodafinil, you will need a prescription to buy it over the counter. Therefore, buying off a reputable online vendor is a popular way of purchasing the smart drug when they are armed with all the right drug information. We recommend ModafinilXL.

This vendor offers a great customer experience, high-quality products, and brand names and work with some of the largest modafinil manufacturers in the business. It’s always advisable to look for a product with a guarantee so that if you are not satisfied you have a 100% money-back guarantee.

Frequently Asked Questions (FAQ)

Your questions answered:

How Much Armodafinil Should I Take?

Most Armodafinil medications come in 150 mg pills and this is why 150 mg is usually the recommended dosage. Tell your doctor if you feel you need to increase or decrease this dosage. Dosage can also depend on the strength and what medical condition you are treating.

What Conditions Does Armodafinil Treat?

It is used to promote wakefulness and decrease excessive sleepiness, whilst treating narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

How is Armodafinil Different from Modafinil?

Armodafinil is an active enantiomer of Modafinil and is generally a lot stronger. The stronger effects can even be felt at a much smaller dose and reach peak effects in half the time than modafinil. This is because the R-modafinil enantiomer in Armodafinil can bind to the active receptor sites easier than the S-modafinil enantiomer.

Can You Take Armodafinil If You are Tired but Don't Have a Sleep Disorder?

Armodafinil should not be used to treat general tiredness or hold off sleep in people who do not suffer from a sleep disorder. Armodafinil is thought to work by affecting certain substances in the brain that control the sleep/wake cycle and should be kept for excessive sleepiness and treating sleep disorders.

Can You Take Armodafinil on Birth Control?

You should not take Armodafinil whilst using birth control methods such as the pill, patch, vaginal rings, implants, injections, or IUDs, as it may decrease the effectiveness of hormonal contraceptives.

How Long Does Armodafinil Last?

Armodafinil has a half-life of around 15 hours. You should take it early in the morning to achieve a cognitive boost and high productivity levels to last you throughout the day whilst also getting enough sleep at night. As different users have different metabolism rates however, some users might experience the effects of the drug for up to 20 hours.

What Happens If You Stop Taking Armodafinil?

Many users will not suffer from severe withdrawal symptoms after stopping the smart drug suddenly. The mild withdrawal symptoms reported however include a decrease in energy levels, reduced alertness, and an increase in sleepiness levels.

It is not recommended to abruptly discontinue using the drug, therefore taper your prescription dose to lower the severity of withdrawal symptoms.


Armodafinil is a smart drug primarily used to treat sleep disorders such as shift work sleep disorder, obstructive sleep apnea, and narcolepsy. It helps to prevent extreme sleepiness and can improve wakefulness whilst also improving cognitive functions.
It should only be taken in doses recommended by your doctor, but in general, this is usually 150 mg.

Although there are some side effects that occur alongside using Armodafinil, it is a generally safe drug to use and these side effects should subside.

We recommend you try one of our online vendors and talk to your doctor about how using armodafinil can benefit you, make you more alert and keep you awake and enthusiastic throughout the working day!