Artvigil: Review of Nootropic Benefits, Uses, Dosage, & Side Effects

Updated on February 9, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
Comprehensive review of Artvigil's nootropic benefits, uses, dosage, and side effects.

In the dynamic and fast-paced world of cognitive enhancers, Artvigil stands out as a prominent name. Artvigil is revered for its ability to enhance wakefulness and alertness, especially among individuals grappling with excessive sleepiness due to conditions like shift work sleep disorder.

With its active ingredient, armodafinil, Artvigil takes action to not only promote wakefulness but also to improve cognitive performance, offering mental clarity even in challenging work schedules.

Could this be the right nootropic for you? Let’s find out.

This article aims to delve into the nuances of Artvigil, providing valuable information for those considering its use as part of their cognitive or therapy regimen.

What is Artvigil?

Artvigil is a generic Armodafinil (also known as Nuvigil), a medication primarily used to help reduce excessive sleepiness associated with conditions like obstructive sleep apnea, narcolepsy, and shift work sleep disorder. 

Artvigil has similar effects to the more widely known Modafinil, as Artvigil enhances wakefulness and alertness in individuals, whilst also boosting cognitive performance.(1)

When using Armodafinil, or its generic versions like Artvigil, it’s important to follow the prescribed dosage, as the medication may have specific dosing requirements that may need a prescription from a doctor. However, this depends on the individual’s health condition and individual response to the drug.

Typically, Artvigill can be purchased online without a prescription, making it a popular product for people in the nootropic community.

In treating obstructive sleep apnea, Artvigil is often part of a broader treatment plan that addresses the underlying sleep disorder and its symptoms.


  • Suitable for those looking for a less-intense, yet effective, version of Armodifinil
  • Improves wakefulness and reduces feelings of sleepiness
  • Improves focus, enhances cognitive function, and increases productivity​


  • Severe side effects associated with misuse
  • Individual responses may vary

Mechanism of Action

Artvigil works primarily by affecting various neurotransmitters in the brain. Its mechanism of action, while not entirely clear, is believed to involve the modulation of brain chemicals that control sleep and wakefulness.

The activive ingredient of Artvigil, Armodafinil, may cross the blood-brain barrier, which allows it to directly influence brain function.(2)

One key neurotransmitter affected by Artvigil is dopamine. It inhibits the reuptake of dopamine, leading to increased levels in the brain.(3) This action contributes to heightened alertness and wakefulness, making Artvigil particularly beneficial for people with sleep disorders like shift work disorder.

By influencing neurotransmitter levels, Artvigil helps regulate sleep cycles to improve focus and concentration.

Nootropic Benefits of Artvigil

The nootropic benefits of Artvigil, a medicinal form of Armodafinil, are numerous and can be particularly advantageous for individuals seeking cognitive enhancement.

Here are some of the key nootropic benefits of Artvigil.

1. Improved Alertness

Taking Armodafinil, the active ingredient in Artvigil, significantly increases alertness, especially for those working in shift work environments.

2. Enhanced Concentration

Since Armodafinil acts on brain neurotransmitters, and it’s the main compound in Artvugil, this medicine may include benefits like improved focus and concentration, essential for productivity in demanding tasks.

3. Better Cognitive Performance

Regular intake of this medicine under proper guidance leads to enhanced overall cognitive performance.

4. Reduced Sleepiness and Fatigue

For individuals struggling with excessive sleepiness, especially due to irregular work shifts, taking Armodafinil within the Artvigil 150 mg capsule can provide much-needed relief.

5. Supports Mental Health

In the context of medical manochikitsa (mental health) and online counseling, Artvigil offers benefits by improving mental clarity and wakefulness, which are vital for active engagement in therapeutic processes.

Uses of Artvigil

Artvigil, as a formulation of Armodafinil, is used primarily to promote wakefulness and enhance cognitive function.

While it’s not specifically indicated for bipolar disorder or depression, its wakefulness-promoting properties can be beneficial in certain cases where these mental conditions are associated with excessive sleepiness or fatigue. 

Artvigil is more commonly prescribed for conditions like narcolepsy, shift work sleep disorder, and obstructive sleep apnea.

However, its impact on mood and cognitive function provides ancillary benefits in managing some symptoms related to bipolar disorder and depression, although this is not its primary use.

Note: It’s crucial to call and consult with a doctor for a proper diagnosis of these conditions.

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ModafinilXL is our top pick for the best place to buy Artvigil.

Artvigil Dosage

The recommended dosage of Artvigil varies depending on the individual’s needs and sensitivity to the medication.

The common Artvigil dosages are as follows:

  • 150 mg: This is the standard recommended dose of Artvigil. One 150 mg pill of Artvigil is typically sufficient to provide cognitive enhancement for at least 12 hours, with benefits such as increased productivity, concentration, and improved memory.
  • 75 mg: A half-dose of 150 mg, or 75 mg, is effective for those who require cognitive enhancement for a typical 9-5 workday without needing extended focus for more than 12 hours. This lower dose is ideal for beginners or those who are more sensitive to the effects of Armodafinil. It provides 6-9+ hours of cognitive enhancement and is less likely to interfere with sleep if taken in the morning.
  • 300 mg: This higher dosage, which is double the standard dose, can provide longer cognitive enhancement (over 20 hours). However, it is not recommended for beginners due to the potential for more pronounced side effects, such as stomach problems and insomnia. This dose should be approached with caution and ideally only after assessing tolerance to lower doses​ with a doctor.

Artvigil Side Effects & Safety

Artvigil is generally well-tolerated, but like all medications, it can have side effects. It’s important to be aware of these potential side effects to ensure safe usage:

Common Side Effects:

  1. Nausea: This can occur, especially when taking Artvigil for the first time, but usually resolves quickly. Staying hydrated can help alleviate this symptom.
  2. Headaches: Some users may experience headaches after taking Artvigil. If headaches persist, it is advisable to consult a doctor.
  3. Diarrhea: While rare, some users might experience an upset stomach.
  4. Dermatitis: Skin irritation or rash can occur, although this is a rare side effect. If this occurs, stop taking the medication and seek medical advice.
  5. Difficulty Sleeping: Given its wakefulness-promoting properties, taking Artvigil too late in the day can disrupt sleep. It’s recommended to take it at least 10 hours before bedtime to avoid this issue.

However, in some cases, severe side effects caused by misuse/overuse may include:

  • Breathing Difficulties
  • Sweating
  • Nervousness
  • Dry Mouth
  • Depression
  • Indigestion/Heartburn
  • Palpitations
  • Agitation
  • Dizziness
  • Numbness/Tingling
  • Fever
  • Rash
  • Appetite Loss
  • Attention Disturbances
  • Anxiety​

If any of these symptoms are experienced, call your doctor immediately.


Artvigil is a popular nootropic medication known for enhancing cognitive function and promoting wakefulness. It is particularly beneficial for individuals with sleep disorders like narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

The standard recommended dosage of Artvigil is 150 mg per day, which can provide cognitive benefits for up to 12 hours. Some people may prefer a lower dose of 75 mg for a shorter duration of effect, while a higher dose of 300 mg is generally not recommended for beginners due to the potential for more pronounced side effects. 

The side effects are generally mild and rare, but if severe side effects are experienced, it is important to seek medical advice. The cognitive enhancements provided by Artvigil often outweigh these minor side effects for most users.

Remember, it’s crucial to consult a healthcare professional before starting Artvigil to ensure its appropriateness for individual health needs.


How long does Artvigil take to work?

Artvigil starts to have an effect about one hour after ingestion, though this may take from 30 minutes to two hours depending on individual differences.

What is the elimination half-life of Artvigil?

The elimination half-life of Armodafinil substance use, the active component in Artvigil, is between 12 to 15 hours. The elimination half-life of Armodafinil substance use, the active component in Artvigil, is between 12 to 15 hours.

Should you cycle Artvigil?

It is advised to take Artvigil only 1-3 times a week to avoid dependence or tolerance issues. Taking the drug every day could lead to a necessity to consume it or a decrease in its effectiveness due to the body building up a tolerance. A break of one to two weeks every two months is recommended to decrease the chance of tolerance development

Can I stack Artvigil with other nootropics?

While there is no specific information regarding the stacking of Artvigil with other nootropics, caution should be exercised. The interactions between different nootropics can vary, and it’s essential to consult a healthcare professional before combining them.

How should I store Artvigil?

Generally, nootropics like Artvigil should be stored in a cool, dry place away from direct sunlight and moisture. It’s important to follow the specific storage instructions provided by the manufacturer or consult a pharmacist for advice.

Sources, Studies, and Scientific Research
  1. Walsh, James K et al. “Modafinil improves alertness, vigilance, and executive function during simulated night shifts.” Sleep vol. 27,3 (2004): 434-9. doi:10.1093/sleep/27.3.434 ↩
  2. Edgar, Christopher J et al. “Approaches to measuring the effects of wake-promoting drugs: a focus on cognitive function.” Human psychopharmacology vol. 24,5 (2009): 371-89. doi:10.1002/hup.1034 ↩
  3. Volkow, Nora D et al. “Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.” JAMA vol. 301,11 (2009): 1148-54. doi:10.1001/jama.2009.351 ↩