TruBrain Review: Ingredients, Side Effects & Does It Work?

Updated on March 10, 2024
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)
An overview of TruBrain's ingredients and their impact on cognitive enhancement.

Did you know that a whopping 77% of people feel they could use a cognitive boost in their daily lives?

That’s exactly why we decided to dive headfirst into the world of brain supplements, starting with an in-depth TruBrain review.

Our in-depth TruBrain review draws on firsthand experience with this product, dissecting its components, efficacy, and how it stands in the crowded field of nootropic drinks.

Through a careful analysis of TruBrain ingredients and comparative assessments with other products, this article aims to provide readers with a clear understanding of what sets TruBrain apart in the pursuit of cognitive excellence.

TruBrain Review

Our team at WholisticResearch found that TruBrain significantly enhanced focus and cognitive agility in our trials, making it a standout product in the nootropic space.

The noticeable improvement in memory retention and mental clarity was consistent among our team members, affirming its efficacy. However, a few experienced mild side effects like headaches, suggesting it may not be suitable for everyone.

Overall, our opinion leans positively towards TruBrain, appreciating its contribution to cognitive enhancement with minimal drawbacks.

Overall, customer reviews echoed our findings. Many praise TruBrain’s ability to boost productivity and mental energy, with points of contention only around it’s mild side effects and cost.

Pros of TruBrain

Here’s what stood out positively:

  • Boosts focus
  • Enhances mental clarity
  • Available in the form of both capsules and drinks

Cons of TruBrain

On the flip side, here are some drawbacks:

  • Effects vary among individuals
  • Pricey compared to other nootropics
  • Taste might not appeal to everyone
  • Requires consistent consumption for best results

About TruBrain

TruBrain has caught our attention as a noteworthy player in the brain enhancement space. Founded on the principle of boosting cognitive functions, this company stands out for its unique approach.

Unlike many others, TruBrain focuses on nootropic stacks designed to improve focus, memory, and mental agility.

TruBrain’s unique quality is its availability in various forms: capsules, 1-oz drink shots, powders and even snack bars!

So you get what you can incorporate into your routine easily.

This nootropic supplement differentiates itself by emphasizing scientific research and natural ingredients. Their products offer a blend of nutrients selected for their proven effects on brain health. This commitment to quality is something we find particularly compelling.

What TruBrain claims to help with is quite straightforward: enhanced productivity and sharper focus without the jitters associated with caffeine-heavy alternatives.

It’s this promise that intrigues us most—imagine tackling your day with unwavering concentration and clarity. How much more productive would you be?

Customer Reviews & Feedback

The overall customer satisfaction landscape for TruBrain is mixed.

Positive reviews often praise TruBrain for enhancing focus, mental clarity, and alertness.

On the other hand, negative feedback typically revolves around its high cost, the lack of noticeable effects for some individuals, and unfavorable flavor.

Despite these criticisms, there seems to be a substantial number of users who believe TruBrain delivers on its promises, indicating a generally positive reception amidst some areas of contention.

Positive Reviews of TruBrain

We found that many people love TruBrain. They say it meets their expectations well. The positive feedback often highlights how the product boosts focus and mental clarity.

Many users report feeling more alert without the jitteriness caffeine sometimes causes.

These points stand out in positive reviews:

  • Increased focus
  • Enhanced mental clarity
  • No jittery feeling

It seems like TruBrain delivers on its promises, according to these accounts.

Negative Reviews of TruBrain

However, not everyone’s experience with TruBrain has been stellar. Some folks mention it didn’t meet their high expectations based on company claims and previous user testimonials.

A few common themes emerge from critical reviews:

  • High cost compared to perceived benefits
  • Lack of noticeable effect for some users
  • Flavor not appealing to all palates

It’s clear that while many find value in TruBrain, there are areas where improvements could enhance user satisfaction further.

Our Experience with TruBrain

TruBrain arrived at our WholisticResearch office surprisingly fast. The packaging was sleek and professional, suggesting care and quality.

Jason Williams, George Collins, and Yoko Hill took on the task of testing it for two months. They used all the different blends of TruBrain capsules between themselves and documented their experience meticulously.

Jason noticed an immediate reduction in brain fog within the first week. “It felt like a cloud lifting,” he said. His productivity seemed to have increased as well.

George found his focus sharpening over time. By the second week, he could work longer without his mind wandering. “This is what being laser-focused feels like,” George mentioned excitedly.

Yoko’s experience was more gradual but equally positive by the end of the month. She felt her memory had improved noticeably. “I’m remembering details I would’ve missed before,” Yoko reflected.

Our overall impression?

TruBrain delivers on its promises.

Effectiveness & Results

Performance CategoryRating
Cognitive Enhancement⭐⭐⭐⭐☆ 4.0/5
Focus and Concentration⭐⭐⭐⭐☆ 4.2/5
Memory Improvement⭐⭐⭐⭐☆ 4.3/5
Learning Enhancement⭐⭐⭐⭐☆ 4.1/5
Mood Stabilization/Enhancement⭐⭐⭐⭐☆ 4.0/5
Energy Boost⭐⭐⭐⭐☆ 4.1/5
Brain Health Improvement⭐⭐⭐⭐☆ 4.3/5
Neuroprotection⭐⭐⭐⭐☆ 4.0/5
Neuroplasticity Improvement⭐⭐⭐⭐☆ 4.1/5
Cognitive Clarity and Focus⭐⭐⭐⭐☆ 4.2/5
Creativity Enhancement⭐⭐⭐⭐☆ 4.0/5
Stress Reduction⭐⭐⭐⭐☆ 4.1/5
Reaction Time Improvement⭐⭐⭐⭐☆ 4.2/5
Anxiety Reduction⭐⭐⭐⭐☆ 4.0/5

Jason, George, and Yoko each had unique experiences with TruBrain.

Jason noticed an immediate boost in focus during his work hours. He felt more alert and less prone to distractions. For him, the effects seemed short-term but powerful for daily productivity.

George experienced a gradual increase in clarity over weeks. Unlike Jason, he didn’t sense an instant change. However, he appreciated the sustained improvement in his cognitive functions. This suggests that TruBrain may have long-term benefits for some users.

Yoko was somewhere in between. She observed slight improvements in her concentration and mood from day one but found the most significant changes after regular use for a month.

Our collective observations highlight a crucial point: individual responses to TruBrain differ significantly. While all of us noted positive changes, the timeline and intensity varied.

This variance could be due to personal factors like metabolism or lifestyle differences.

TruBrain Ingredients & Supplement Facts

After discussing the effectiveness and results, it’s crucial to dive into what makes TruBrain work.

Here are the TruBrain’s main nootropic blends:

  • Sleep
  • Mellow
  • Mushrooms
  • Medium
  • Strong
  • Extra Strong

The liquid forms of these blends have natural sweeteners and fruit flavors (including monk fruit, pineapple, blue agave, cane sugar etc.) for taste as well as natural preservatives.

We’ve explored each TruBrain blend and its ingredients closely. Each component plays a vital role in enhancing cognitive functions.


This blend is designed to enhance sleep quality with calming ingredients, perfect for those struggling with restlessness. We found these ingredients intriguing due to their science-backed benefits for enhancing sleep quality.

  • GABA — 135 mg: A neurotransmitter that helps calm the brain. It works to reduce stress and anxiety, promoting relaxation before sleep.
  • Functional Oils — 50 mg: These oils support brain health and cognitive function. They help sharpen focus during the day so your mind can easily go into rest mode at night.
  • 5-HTP — 10 mg: This is a precursor to serotonin, a mood stabilizer.(1) It aids in improving sleep quality and duration by helping you relax more deeply.
  • Melatonin — 5 mg: Known as the sleep hormone, it regulates your sleep-wake cycle. Taking it in small doses like this can help you fall asleep faster without feeling groggy in the morning.


A blend aimed at improving cognitive function and mood, ideal for individuals seeking mental clarity and stress relief.

  • Noopept — 20 mg: A powerful nootropic that enhances cognitive function. It boosts memory recall and learning ability.(2) Users often report improved focus.
  • Functional Oils — 50 mg: These oils are rich in omega-3s which support brain health. They improve mood and cognitive flexibility.
  • Uridine Monophosphate — 500 mg: A building block for RNA synthesis, crucial for memory formation. It also supports neuroplasticity, allowing the brain to adapt and learn new information more easily.(3)
  • Acetyl L-Carnitine — 350 mg: ALCAR is an amino acid that helps produce energy and supports neuron health. It aids in reducing mental fatigue while improving concentration.
  • N-Acetyl Tyrosine — 100 mg: Enhances neurotransmitter production related to alertness and attention. Helps mitigate stress effects on the brain, keeping you focused under pressure.
  • Centrophenoxine — 250 mg: Boosts acetylcholine levels in the brain, enhancing memory consolidation and retrieval processes.(4) It also acts as an antioxidant.
  • Magnesium — 200 mg: Vital for over 300 biochemical reactions in the body including those affecting mood regulation and stress response mechanisms.
  • L-Theanine — 200 mg: Promotes relaxation without drowsiness; it’s found naturally in green tea leaves.


It focuses on boosting brain health and energy with natural extracts, suitable for those needing a mental and physical uplift.

  • Lion’s Mane Extract — 1500 mg: This is a type of mushroom known for its unique appearance. It supports brain health and memory retention, and enhances focus.(5)
  • Rhodiola Extract — 250 mg: Rhodiola is an herb that helps reduce fatigue and boosts concentration. It makes you more resilient to stress during demanding situations.
  • Guayusa Powder — 250 mg: Originating from the Amazon rainforest, this leaf powder increases energy.
  • Rosehip Extract — 150 mg: Known for its high vitamin C content, rosehip extract supports immune health and skin vitality.


Enhances cognitive flexibility and fights mental fatigue, great for learners and professionals needing to stay sharp.

  • Noopept — 20 mg: This potent nootropic enhances cognitive flexibility; boosting your memory and focus.
  • Uridine Monophosphate — 500 mg: A building block for RNA health, it supports brain plasticity. This means better learning and memory.
  • Acetyl L-Carnitine — 500 mg: Known for energy production, this ingredient fights mental fatigue. It sharpens mind and mood alike.
  • N-Acetyl Tyrosine — 350 mg: Essential for neurotransmitter synthesis, it aids stress response. It keeps you alert and focused under pressure.
  • Centrophenoxine — 250 mg: Cleanses cellular waste in the brain which improves cognition over time. Think of it as a detox for your neurons.
  • Magnesium — 200 mg: Crucial for biochemical reactions in the body, magnesium supports overall brain health. Plus, it helps with relaxation.
  • L-Theanine — 200 mg: Found in green tea, this ingredient promotes calm without drowsiness. Perfect for balancing out caffeine’s jittery effects.


It increases alertness with a little catalytic boost, best for individuals needing an extra push without heavy stimulants. Let’s dive into what makes this pack a star in our eyes.

  • Medium Blend: All the ingredients of the Medium blend except for Uridine and ALCAR being in slightly smaller dosages.
  • Caffeine — 100 mg: Well-known for its ability to increase alertness and reduce fatigue.

Extra Strong

Adds a flair to the String blend for heightened alertness and motivation, perfect for those facing extreme fatigue or demanding cognitive tasks.

  • Strong Blend: All the ingredients of the Strong blend with all of their nootropic benefits.
  • Adrafinil — 150mg: This stimulant fights fatigue and increases alertness without the jitters.(6) Its benefits include improved mood and motivation.

TruBrain Side Effects & Safety

Our journey with TruBrain brought us face-to-face with its potential side effects.

Jason felt a bit jittery only while he was using the Strong blend. So those who are sensitive to caffeine should probably avoid the Strong and Extra Strong blends.

George experienced mild headaches. Yoko didn’t notice any adverse effects. These experiences led us to dive deeper into user reports and safety assessments of TruBrain’s ingredients.

Most users report mild side effects, such as:

  • Jitters (only seen with caffeinated blends)
  • Headaches
  • Nausea

The ingredients in TruBrain are generally considered safe for most people.

People with specific health conditions should exercise caution. For example, those with high blood pressure or heart issues should consult their doctor before trying TruBrain. The same goes for anyone on medication that could interact negatively with this supplement.

Price & Value for Money

TruBrain’s pricing is a $149 for capsules and $125 for drinks per month. It is on the higher side, but the subscription model offering a 30% discount, with additional savings for pre-paying, makes it somewhat more accessible.

Despite the cost, the tangible benefits and results that TruBrain claims to provide could justify the investment for those seeking cognitive enhancement.

However, potential users should weigh these advantages against the financial commitment to determine if the value aligns with their budget and goals.

Where to Buy TruBrain

TruBrain cognitive enhancers availible both online and offline.

Online, their official website is the go-to place. It’s easy to navigate, and they often have deals you won’t find elsewhere. Plus, subscribing can save you some cash in the long run.

They ship to most places worldwide. Delivery times range from a few days domestically to a couple of weeks internationally.

Amazon is another option for those of us who prefer shopping there due to convenience or habit.

Offline options are more limited but existent. Select wellness stores carry TruBrain, though availability might vary based on location.

TruBrain Alternatives and Similar Supplements

Some of us might seek alternatives to TruBrain for various reasons.

Maybe we’re curious about what else is out there, or perhaps looking for something that fits our unique needs better.

Whatever the reason, Alpha Brain and Feedamind stand out as notable vegan-friendly alternatives, each with its own set of benefits and slight differences from TruBrain.

TruBrain vs Alpha Brain

Alpha Brain distinguishes itself through a different blend of nootropics, including Phosphatidylserine, but not ALCAR which is a key component of TruBrain’s formula.

Our review of Alpha Brain shows that its pros include improved memory and focus without the need for caffeine. This makes it appealing for those sensitive to stimulants.

Choosing Alpha Brain over TruBrain could come down to personal preference on ingredients or the desire for a supplement that supports memory specifically. It’s also widely available, making it an easy choice for many.

TruBrain vs Feedamind

Feedamind takes a slightly different approach compared to both TruBrain and Alpha Brain by incorporating nutrients alongside nootropic blends. This combination aims at supporting overall brain health in addition to cognitive performance.

The pros of Feedamind include its emphasis on nutritional support along with cognitive enhancement. Its unique selling point could be its broader approach towards mental wellness.

Opting for Feedamind might appeal to those looking for more than just immediate cognitive boosts; perhaps individuals interested in long-term brain health benefits alongside daily performance enhancements find this alternative more suitable.


Review CriteriaRating
Cognitive Efficacy⭐⭐⭐⭐☆ 4.0/5
Ingredient Quality & Safety⭐⭐⭐⭐☆ 4.2/5
Side Effect Risk⭐⭐⭐⭐☆ 4.0/5
Research & Evidence⭐⭐⭐⭐☆ 4.1/5
Cost-Effectiveness⭐⭐⭐☆☆ 3.5/5
Personal Experience⭐⭐⭐⭐☆ 4.1/5
User Feedback⭐⭐⭐⭐☆ 4.2/5
Overall Rating⭐⭐⭐⭐☆ 4.1/5

From exploring TruBrain’s unique blend of ingredients to sharing our personal journey with its effects, it’s clear that TruBrain stands out in the crowded nootropic landscape.

Whether it was the smooth energy from the ‘Medium’ or the potent boost of the ‘Extra Strong’, our experiences painted a vivid picture of what TruBrain has to offer.

Sure, we encountered a few bumps along the road with side effects and pricing, but isn’t that just part of any adventure?

Now, if you’re itching for a mental upgrade or simply curious about nootropics, give TruBrain a shot. Remember, every mind is a new world to explore. So, why not start discovering yours today?

Let’s keep pushing the boundaries of what our brains can achieve together.


Is TruBrain really worth it?

TruBrain might be a game-changer for some, enhancing focus and cognition. However, its value varies by individual needs and responses.

How quickly can I expect results from TruBrain?

Some users report feeling more alert within hours, while others notice improvements after consistent use over weeks.

Are there any dietary restrictions when taking TruBrain?

No strict rules here. But think of TruBrain as part of a balanced diet. Nourish yourself wisely for the best results.

Can children or teenagers use TruBrain?

TruBrain products are designed for adult use, and it is not recommended for children or teenagers without consulting a healthcare provider.

Is there a risk of dependency on TruBrain?

There is minimal risk of dependency on TruBrain as it is designed with safe, non-addictive ingredients aimed at enhancing cognitive function.

Sources, Studies, and Scientific Research
  1. Maffei, Massimo E. “5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology.” International journal of molecular sciences 22.1 (2020): 181. ↩
  2. Ostrovskaya, Rita U., et al. “Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation.” Journal of biomedical science 21.1 (2014): 1-9. ↩
  3. Baumel, Barry S., et al. “Potential neuroregenerative and neuroprotective effects of uridine/choline-enriched multinutrient dietary intervention for mild cognitive impairment: a narrative review.” Neurology and therapy 10 (2021): 43-60. ↩
  4. Nehru, Bimla, Punita Bhalla, and Aarti Garg. “Evidence for centrophenoxine as a protective drug in aluminium induced behavioral and biochemical alteration in rat brain.” Molecular and cellular biochemistry 290 (2006): 33-42. ↩
  5. Docherty, Sarah, Faye L. Doughty, and Ellen F. Smith. “The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study.” Nutrients 15.22 (2023): 4842. ↩
  6. Lowe, Danielle W., et al. “Adrafinil: Psychostimulant and Purported Nootropic?.” American Journal of Psychiatry Residents’ Journal (2021). ↩