Phenibut and Kratom: Stacks, Facts, & Dangers

Updated on February 26, 2023
 by — reviewed by Jason Williams, PhD (Contributor: George Collins / Editor: Yoko Hill)

Phenibut and Kratom are two legal drugs that have begun to surge in popularity.

Often, mixing the two produces a euphoric high.

The use of synthetic psychotropics is rapidly increasing across the globe

It is sometimes used recreationally and sometimes as prescribed medicine.

Here, we discuss mixing Phenibut with Kratom, along with its effects and the dangers of combining the two drugs.

Phenibut Overview

Phenibut originated in Russia. However, in the United States, it has never been approved as a medication.

phenibut structure

This drug was initially designed to clone GABA acids, which are usually produced naturally by the brain. GABA acids, and Phenibut, were known to counter various emotional and mental issues such as fear, stress, and depression.

Based on reviews, the feelings of happiness and euphoria after using Phenibut have earned the nickname of the “happy drug.”

Benefits and Effects

The Phenibut supplement is believed to help treat anxiety, fear, sleep problems, stress and tension, fatigue, post-traumatic stress disorder, depression, alcoholism, and irregular heartbeat.

phenibut benefits effects

It is also believed to promote memory, learning, and cognitive abilities.

The effects of Phenibut include muscle relaxation, sedation, and a strong sense of calmness and well-being.

If used irresponsibly, symptoms could progress to dangerous extremes, including addiction. And once you abruptly stop taking it, it would lead you to Phenibut withdrawal.

Kratom for Phenibut withdrawal will help as you will not need anything too stimulating when you’re coming off a Phenibut habit.

But you should taper with Kratom too, to save it for times when you need it, such as if you feel anxious or you can’t sleep.

Kratom will allow you to get full nights’ sleep most nights during your taper, and as a result, you will be able to taper faster than you would have otherwise.

Kratom Overview

Kratom is a 100% all-natural plant grown most commonly throughout Southeast Asia (particularly in Thailand, Malaysia, and Vietnam). This is an indigenous tree that has been used for centuries for its psychoactive effects.

kratom overview

Kratom is known for its near opiate-like aftereffects. People report feelings of sedation and reduced pain when using it.

Benefits and Effects

Using Kratom in smaller amounts is enough to increase energy, alertness, and social feelings.

After Kratom consumption, you will feel euphoria, mental stimulation, analgesia, and mood-boost.

kratom benefits effects

Its side effects include nausea, sweating, itching, constipation, dry mouth, loss of appetite, hallucinations, seizures, and psychosis.

Additionally, research shows that infants may be exposed to kratom through breastfeeding. When this occurs, an infant may go into withdrawal. Women who use kratom while pregnant may also expose their children to this risk.

Kratom withdrawal symptoms include achy muscles, aggression, anxiety, depression, diarrhea, hostility, insomnia, irritability, jerky movements, nausea and vomiting, runny nose, shifting emotions, stomach cramping, and sweating.

Phenibut for Kratom withdrawal would end up needing something to quit Phenibut in the end.

This would be a terrible idea since Kratom wreaks havoc on the adrenals. Phenibut leaves the body stimulated and alleviates any of the opioid receptors.

It’s usually used the other way around, and it’s a different experience than that of the Phenibut.

Taking Phenibut and Kratom Together

The combined use of Kratom and Phenibut is becoming increasingly popular, especially among patients with co-occurring opioid and alcohol use disorders.

phenibut and kratom featured image

Many people may combine Phenibut with Kratom to alleviate pain and opiate withdrawal syndrome.

Recreationally, the two combinations can cause a very strong high. The mixture is thought to produce a more natural state of euphoria.

Despite being legal throughout much of the United States, this mixture’s dangers may be even greater.

To get more of the health benefits of each of the substances individually, Phenibut should be administered in high doses. However, you can also increase the aftereffects without necessarily increasing dosages by combining them.

According to users on different drug forums and Reddit, the results are excellent. Combining Kratom and Phenibut takes you to the next level.

People reported they felt a sense of euphoria, and they’re more mentally alert and focused. It boosts mood and causes analgesia.

However, Phenibut Kratom withdrawal would often lead to using Phenibut to relieve the anxiety brought by the combination. This is not recommended as it might have adverse effects on mental health.

Benefits of Combining Phenibut and Kratom

The combination of Kratom and Phenibut can help to almost entirely deal with PTSD, stress, depression, and anxiety symptoms.

The effects can also improve social life, such as converting introverts into extroverts and increasing productivity.

Kratom and Phenibut, when used alone and in low dosages, will naturally increase your energy levels. While combining it results in increased libido, especially in men.

Studies indicate that individuals who combine Phenibut and Kratom tend to perform better in bed and have a better time during the process, including getting prolonged and more intense orgasms.

Side Effects and Risks

According to Reddit users, they felt side effects like grogginess following the continuous use of Phenibut with Kratom.

Despite their stimulating properties, both substances can have central nervous system depressant effects, in which mental health would be significantly affected.

This means that they could slow down critical life support systems in the body. These systems are responsible for regulating blood pressure, breathing, heart, and temperature rates.

The combination may also lead to severe intoxication and dangerous withdrawal symptoms, such as breathing problems, hallucinations, psychosis, and unconsciousness.

Like other drugs, the higher or more frequent dose of the Phenibut-Kratom combination poses a greater risk of tolerance, dependence, addiction, and withdrawal.

Phenibut Mixed with Other Drugs

Phenibut does not only treat anxiety and depression. It is also often being consumed for recreation.

Other substances are used with Phenibut to enhance the effects and get high.

However, recreational use is considered abuse. It does not come without risks, as adverse side effects, tolerance, and dependence are very common.

Like any drug, the impact of Phenibut will be experienced differently by each individual depending on various factors, such as age, weight, body composition, metabolism, and use of any other drugs and medications.

More research needs to be conducted on the lasting impacts of Phenibut when taken medicinally and when mixed with other drugs.

Is Mixing Phenibut and Kratom Dangerous?

People have combined the two in an attempt to alleviate pain from opiate withdrawal symptoms. Phenibut can help extend the “high” from Kratom as well.

When taken recreationally, the combination of Phenibut and Kratom can produce a very strong high. Hence, it can be powerfully addictive. Users who take this combination for opiate withdrawal syndrome often report replacement addiction.

So, Phenibut vs. Kratom, which is better? Individually, it can cause dependence, addiction, withdrawal, overdose, or death. When combined or used with other drugs, these effects could intensify and become more severe.

This combination may also lead to severe intoxication and dangerous withdrawal symptoms, such as breathing problems, hallucinations, psychosis, and unconsciousness.

At low dosages, it will have more of a stimulating effect, with a mild high. The mix will be more sedative at high doses and probably knock you out for the entire night.

When mixing Kratom and Phenibut, a person could face a higher risk of agitation, depression, hallucinations, heart problems, intoxication, sedation, seizures, and withdrawal.


When it comes to Phenibut, too little is known about the drug to label it safe for consumption on its own or when mixed with other drugs.

It has grown widely in popularity due to its affordability, easy access, and promises of producing a good mood.

Kratom has grown significantly over the recent past, with many people using it to relieve pain and treat sleep disorders.

However, Kratom can have some temporary side-effects when used in high doses. Instead of overdosing, people prefer combining it with Phenibut.

You need to be extra careful with dosing as a higher dose of Phenibut can result in unpleasant effects that could lead to addiction.

However, medical professionals warn about substance abuse when self-medicating to avoid any adverse effects.